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1,4-Cyclohexanedimethanol | CAS:105-08-8
1,4-Cyclohexanedimethanol
  • Name:1,4-Cyclohexanedimethanol
  • CAS:105-08-8
  • Synonyms:1,4-Bis(hydroxymethyl)cyclohexane; CHDM
  • Molecular Formula:C8H16O2
  • Molecular Weight:144.21
  • EINESC:203-268-9

Description

Properties

Melting point 31.5 ºC
Water Solubility miscible
Boiling point 283 ºC
Flash point 161 ºC

Safety

Hazard Codes R36
SDS/MSDS S26;S39

SDS

Source SDS/MSDS Samples
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Synthetic Route
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Articles
Peer-Reviewed Papers
Analytical method development for directed enzyme evolution research: a high throughput high-performance liquid chromatography method for analysis of ribose and ribitol and a capillary electrophoresis method for the separation of ribose enantiomers.Baoguo Sun et al.Journal of chromatography. A, 1271(1), 163-169 (2012-12-15) Exogenous glycine and serine promote growth and antifungal activity of Penicillium citrinum W1 from the south-west Indian Ocean.Chang-wen Wu et al.FEMS microbiology letters, 362(8), fnv040-fnv040 (2015-03-13) Application of gas chromatography/flame ionization detector-based metabolite fingerprinting for authentication of Asian palm civet coffee (Kopi Luwak).Udi Jumhawan et al.Journal of bioscience and bioengineering, 120(5), 555-561 (2015-04-29) Pentosidine and N(epsilon)-(carboxymethyl)-lysine in Alzheimer's disease and vascular dementia.K J Bär et al.Neurobiology of aging, 24(2), 333-338 (2002-12-25) Genetic characterization of a complex locus necessary for the transport and catabolism of erythritol, adonitol and L-arabitol in Sinorhizobium meliloti.Barney A Geddes et al.Microbiology (Reading, England), 158(Pt 8), 2180-2191 (2012-05-23) ISPD Overexpression Enhances Ribitol-Induced Glycosylation of α-Dystroglycan in Dystrophic FKRP Mutant Mice.Marcela P Cataldi et al.Molecular therapy. Methods & clinical development, 17, 271-280 (2020-01-29) Mitochondrial involvement and erythronic acid as a novel biomarker in transaldolase deficiency.Udo F H Engelke et al.Biochimica et biophysica acta, 1802(11), 1028-1035 (2010-07-06) A novel scoring system for prognostic prediction in d-galactosamine/lipopolysaccharide-induced fulminant hepatic failure BALB/c mice.Bo Feng et al.BMC gastroenterology, 9, 99-99 (2009-12-31) N-Arylmethyl substituted iminoribitol derivatives as inhibitors of a purine specific nucleoside hydrolase.Annelies Goeminne et al.Bioorganic & medicinal chemistry, 16(14), 6752-6763 (2008-06-24) Sorbitol dehydrogenase is a cytosolic protein required for sorbitol metabolism in Arabidopsis thaliana.María Francisca Aguayo et al.Plant science : an international journal of experimental plant biology, 205-206, 63-75 (2013-03-19) Neutral monosaccharides and their relationship to metal contamination in mangrove sediments.Dandan Duan et al.Chemosphere, 251, 126368-126368 (2020-03-17) Bis[(1S)-1,4-azanediyl-1-(9-deazaadenin-9-yl)-1,4-dideoxy-5-methylsulfanyl-D-ribitol] tetrakis(hydrochloride) monohydrate: structure, DFT energy and ligand docking results of a potent methylthioadenosine phosphorylase inhibitor found in different molecular conformations.Graeme J Gainsford et al.Acta crystallographica. Section C, Crystal structure communications, 66(Pt 11), o527-o530 (2010-11-06) Trabulsiella guamensis, a new genus and species of the family Enterobacteriaceae that resembles Salmonella subgroups 4 and 5.A C McWhorter et al.Journal of clinical microbiology, 29(7), 1480-1485 (1991-07-01) In vivo and in vitro NMR spectroscopy reveal a putative novel inborn error involving polyol metabolism.S H Moolenaar et al.NMR in biomedicine, 14(3), 167-176 (2001-05-18) Monitoring of chemical elements and oxidative damage in patients affected by Alzheimer's disease.Beatrice Bocca et al.Annali dell'Istituto superiore di sanita, 41(2), 197-203 (2005-10-26) Formation of the two novel glycolipid biosurfactants, mannosylribitol lipid and mannosylarabitol lipid, by Pseudozyma parantarctica JCM 11752T.Tomotake Morita et al.Applied microbiology and biotechnology, 96(4), 931-938 (2012-06-23) Anti-cancer activity of 5-O-alkyl 1,4-imino-1,4-dideoxyribitols.Claudia Bello et al.Bioorganic & medicinal chemistry, 19(24), 7720-7727 (2011-11-15) Differential regulation of defense-related proteins in soybean during compatible and incompatible interactions between Phytophthora sojae and soybean by comparative proteomic analysis.Maofeng Jing et al.Plant cell reports, 34(7), 1263-1280 (2015-04-24) Liver functional metabolomics discloses an action of L-leucine against Streptococcus iniae infection in tilapias.Yan-Mei Ma et al.Fish & shellfish immunology, 45(2), 414-421 (2015-05-11) Understanding thermodynamic properties at the molecular level: multiple temperature charge density study of ribitol and xylitol.Anders Østergaard Madsen et al.The journal of physical chemistry. A, 115(26), 7794-7804 (2011-06-15) Recognition of riboflavin and the capsular polysaccharide of Haemophilus influenzae type b by antibodies generated to the haptenic epitope D-ribitol.G Ravi et al.Glycoconjugate journal, 31(3), 247-258 (2014-03-20) Leminorella, a new genus of Enterobacteriaceae: identification of Leminorella grimontii sp. nov. and Leminorella richardii sp. nov. found in clinical specimens.F W Hickman-Brenner et al.Journal of clinical microbiology, 21(2), 234-239 (1985-02-01) Human embryoid bodies as a 3D tissue model of the extracellular matrix and α-dystroglycanopathies.Alec R Nickolls et al.Disease models & mechanisms, 13(6) (2020-05-20) Utilization of D-ribitol by Lactobacillus casei BL23 requires a mannose-type phosphotransferase system and three catabolic enzymes.A Bourand et al.Journal of bacteriology, 195(11), 2652-2661 (2013-04-09) Effect of diabetes on the free polyol pattern in cataractous lenses.S Yoshioka et al.Clinical chemistry, 37(5), 686-689 (1991-05-01) Synthesis of CDP-activated ribitol for teichoic acid precursors in Streptococcus pneumoniae.Stefanie Baur et al.Journal of bacteriology, 191(4), 1200-1210 (2008-12-17) A synchrotron radiation study of the one-dimensional complex of sodium with (1S)-N-carboxylato-1-(9-deazaadenin-9-yl)-1,4-dideoxy-1,4-imino-D-ribitol, a member of the 'immucillin' family.Graeme J Gainsford et al.Acta crystallographica. Section C, Crystal structure communications, 66(Pt 3), m65-m68 (2010-03-06) N-acetylglucosamine enhances survival ability of tilapias infected by Streptococcus iniae.Zhi-xue Cheng et al.Fish & shellfish immunology, 40(2), 524-530 (2014-08-15) Metabolome analysis of gram-positive bacteria such as Staphylococcus aureus by GC-MS and LC-MS.Manuel Liebeke et al.Methods in molecular biology (Clifton, N.J.), 815, 377-398 (2011-12-02) Selective removal of phosphate for analysis of organic acids in complex samples.Sandeep Deshmukh et al.Journal of chromatography. A, 1388, 1-8 (2015-03-01) Anti-cancer activity of 5-O-alkyl 1,4-imino-1,4-dideoxyribitols.Claudia Bello et al.Bioorganic & medicinal chemistry, 19(24), 7720-7727 (2011-11-15) SIRT3 deficiency impairs mitochondrial and contractile function in the heart.Christoph Koentges et al.Basic research in cardiology, 110(4), 36-36 (2015-05-13) Glycerophosphocholine is elevated in cerebrospinal fluid of Alzheimer patients.Anna Walter et al.Neurobiology of aging, 25(10), 1299-1303 (2004-10-07) Utilization of D-ribitol by Lactobacillus casei BL23 requires a mannose-type phosphotransferase system and three catabolic enzymes.A Bourand et al.Journal of bacteriology, 195(11), 2652-2661 (2013-04-09) Fast responses of metabolites in Vicia faba L. to moderate NaCl stress.Christoph-Martin Geilfus et al.Plant physiology and biochemistry : PPB, 92, 19-29 (2015-04-23) Leminorella, a new genus of Enterobacteriaceae: identification of Leminorella grimontii sp. nov. and Leminorella richardii sp. nov. found in clinical specimens.F W Hickman-Brenner et al.Journal of clinical microbiology, 21(2), 234-239 (1985-02-01) Human embryoid bodies as a 3D tissue model of the extracellular matrix and α-dystroglycanopathies.Alec R Nickolls et al.Disease models & mechanisms, 13(6) (2020-05-20) Synthesis of CDP-activated ribitol for teichoic acid precursors in Streptococcus pneumoniae.Stefanie Baur et al.Journal of bacteriology, 191(4), 1200-1210 (2008-12-17) Proteomic and metabolomic analysis of the carotenogenic yeast Xanthophyllomyces dendrorhous using different carbon sources.Pilar Martinez-Moya et al.BMC genomics, 16, 289-289 (2015-04-19) Ribose-5-phosphate isomerase deficiency: new inborn error in the pentose phosphate pathway associated with a slowly progressive leukoencephalopathy.Jojanneke H J Huck et al.American journal of human genetics, 74(4), 745-751 (2004-02-28) The human cerebrospinal fluid metabolome.David S Wishart et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 871(2), 164-173 (2008-05-27) Free amino acid and dipeptide changes in the body fluids from Alzheimer's disease subjects.A N Fonteh et al.Amino acids, 32(2), 213-224 (2006-10-13) Relationship of CDC group EO-2 and psychrobacter immobilis.M J Hudson et al.Journal of clinical microbiology, 25(10), 1907-1910 (1987-10-01) Metabolic Profiling of Dendrobium officinale in Response to Precursors and Methyl Jasmonate.Chunyan Jiao et al.International journal of molecular sciences, 19(3) (2018-03-08) Anionic Lipids Modulate the Activity of the Aquaglyceroporin GlpF.Noreen Klein et al.Biophysical journal, 109(4), 722-731 (2015-08-20) Effect of diabetes on the free polyol pattern in cataractous lenses.S Yoshioka et al.Clinical chemistry, 37(5), 686-689 (1991-05-01) L-proline increases survival of tilapias infected by Streptococcus agalactiae in higher water temperature.Xian-Liang Zhao et al.Fish & shellfish immunology, 44(1), 33-42 (2015-02-11) Combined transcript, proteome, and metabolite analysis of transgenic maize seeds engineered for enhanced carotenoid synthesis reveals pleotropic effects in core metabolism.Mathilde Decourcelle et al.Journal of experimental botany, 66(11), 3141-3150 (2015-03-22) Capillary gas chromatography combined with ion trap detection for quantitative profiling of polyols in cerebrospinal fluid and plasma.H U Shetty et al.Analytical biochemistry, 224(1), 279-285 (1995-01-01) A new member of the family Enterobacteriaceae--Pragia fontium.E Aldová et al.Journal of hygiene, epidemiology, microbiology, and immunology, 32(4), 433-436 (1988-01-01) Comparison of a new enzyme-linked immunosorbent assay method with counterimmunoelectrophoresis for detection of teichoic acid antibodies in sera from patients with Staphylococcus aureus infections.C Herzog et al.Journal of clinical microbiology, 19(4), 511-515 (1984-04-01) Active site plasticity revealed from the structure of the enterobacterial N-ribohydrolase RihA bound to a competitive inhibitor.Gianpiero Garau et al.BMC structural biology, 10, 14-14 (2010-06-10) Urinary metabolic fingerprinting of mice with diet-induced metabolic derangements by parallel dual secondary column-dual detection two-dimensional comprehensive gas chromatography.Davide Bressanello et al.Journal of chromatography. 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