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Isopropyl chloroacetate | CAS:105-48-6
Isopropyl chloroacetate
  • Name:Isopropyl chloroacetate
  • CAS:105-48-6
  • Synonyms:(1-Methylethyl)-2-chloroacetate
  • Molecular Formula:C5H9ClO2
  • Molecular Weight:136.58
  • EINESC:203-301-7

Description

Properties

Water Solubility slightly soluble
Boiling point 149-150 ºC
Flash point 56 ºC
Density 1.096
Refractive index 1.418-1.42

Safety

Symbol(GHS) T
Hazard Codes R10;R25;R36/37/38
SDS/MSDS S26;S37/39;S45

SDS

Source SDS/MSDS Samples
没有数据没有数据
Synthetic Route
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Articles
Peer-Reviewed Papers
Electrochemiluminescence determination of nitro polycyclic-aromatic hydrocarbons using HPLC separation.Chen X, et al. Chromatographia, 58(9-10), 571-577 (2003) Comparative mutagenicity of nitrofluoranthenes in Salmonella typhimurium TA98, TA98NR, and TA98/1,8DNP6.B S Shane et al.Environmental and molecular mutagenesis, 17(2), 130-138 (1991-01-01) 3-Nitrofluoranthene (3-NF) but not 3-aminofluoranthene (3-AF) elicits apoptosis as well as programmed necrosis in Hepa1c1c7 cells.Nana Asare et al.Toxicology, 255(3), 140-150 (2008-12-02) Diurnal/nocturnal concentrations and sources of particulate-bound PAHs, OPAHs and NPAHs at traffic and suburban sites in the region of Paris (France).Johany Ringuet et al.The Science of the total environment, 437, 297-305 (2012-09-06) Multivariate QSAR study on the antimutagenic activity of flavonoids against 3-NFA on Salmonella typhimurium TA98.Eduardo Borges de Melo et al.European journal of medicinal chemistry, 45(10), 4562-4569 (2010-08-11) Pulmonary carcinogenicity of 3,9- and 3,7-dinitrofluoranthene, 3-nitrofluoranthene and benzo[a]pyrene in F344 rats.K Horikawa et al.Carcinogenesis, 12(6), 1003-1007 (1991-06-01) Inhibition of the mutagenicity of 2-nitrofluorene, 3-nitrofluoranthene and 1-nitropyrene by vitamins, porphyrins and related compounds, and vegetable and fruit juices and solvent extracts.X Tang et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 35(3-4), 373-378 (1997-03-01) Characterization of oxidative and reductive metabolism in vitro of nitrofluoranthenes by rat liver enzymes.M A Belisario et al.Carcinogenesis, 11(2), 213-218 (1990-02-01) Comparative lung tumorigenicity of parent and mononitro-polynuclear aromatic hydrocarbons in the BLU:Ha newborn mouse assay.W F Busby et al.Toxicology and applied pharmacology, 99(3), 555-563 (1989-07-01) Determination of 3-nitrofluoranthene and 1-nitropyrene in suspended particulate matter by liquid chromatography with fluorescence detection.Kamiura T, et al. Analytica Chimica Acta, 254(1), 27-31 (1991) Fungal metabolism of 3-nitrofluoranthene.J V Pothuluri et al.Journal of toxicology and environmental health, 42(2), 209-218 (1994-06-01) Fungal metabolism of nitrofluoranthenes.J V Pothuluri et al.Journal of toxicology and environmental health. Part A, 53(2), 153-174 (1998-01-28) Erythrocyte enzymes catalyze 1-nitropyrene and 3-nitrofluoranthene nitroreduction.M A Belisario et al.Toxicology, 108(1-2), 101-108 (1996-04-15) Inhibition of the mutagenicity of 2-nitrofluorene, 3-nitrofluoranthene and 1-nitropyrene by flavonoids, coumarins, quinones and other phenolic compounds.R Edenharder et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 35(3-4), 357-372 (1997-03-01) Structure of phenolic isomers of 2- and 3-nitrofluoranthene studied by one- and two-dimensional 1H NMR spectroscopy. Comparative analysis of mutagenicity.F E Evans et al.Chemical research in toxicology, 7(3), 352-357 (1994-05-01) Kinetics and cofactor requirements for the nitroreductive metabolism of 1-nitropyrene and 3-nitrofluoranthene by rabbit liver aldehyde oxidase.S L Bauer et al.Carcinogenesis, 12(9), 1545-1549 (1991-09-01) Carcinogenicity in rats of the mutagenic compounds 1-nitropyrene and 3-nitrofluoranthene.H Ohgaki et al.Cancer letters, 15(1), 1-7 (1982-01-01) Study of nitro-polycyclic aromatic hydrocarbons in particulate matter in Dongguan.Shan-Hong Lan et al.Environmental science and pollution research international, 21(12), 7390-7399 (2014-03-01) 3-nitrofluoranthene (3-NF)-induced apoptosis and programmed necrosis.Nana Asare et al.Autophagy, 5(5), 751-752 (2009-05-19) Metabolic activation of the genotoxic environmental contaminants 2- and 3-nitrofluoranthene in variants of Salmonella typhimurium TA98.L M Ball et al.Mutagenesis, 10(6), 497-504 (1995-11-01) 1H NMR studies on mutagenic nitrofluoranthenes and exposure risk assessment.G L Squadrito et al.Chemical research in toxicology, 3(3), 231-235 (1990-05-01) The role of cytochrome P450 2C3 in rabbit liver microsomal metabolism of 1-nitropyrene and 3-nitrofluoranthene.P C Howard et al.Journal of biochemical toxicology, 9(2), 71-78 (1994-04-01) The kinetics of 1-nitropyrene and 3-nitrofluoranthene metabolism using bovine liver xanthine oxidase.S L Bauer et al.Cancer letters, 54(1-2), 37-42 (1990-10-08) Polycyclic nitroarenes (nitro-PAHs) as biomarkers of exposure to diesel exhaust.I Zwirner-Baier et al.Mutation research, 441(1), 135-144 (1999-05-04) Identification and characterization of the major DNA adduct formed chemically and in vitro from the environmental genotoxin 3-nitrofluoranthene.A M Dietrich et al.Carcinogenesis, 9(11), 2113-2119 (1988-11-01) Experimental and theoretical study of vibrational spectra of 3-nitrofluoranthene. Onchoke KK and Parks M. Journal of Molecular Structure, 999(1), 22-28 (2011) Signalling pathways involved in 1-nitropyrene (1-NP)-induced and 3-nitrofluoranthene (3-NF)-induced cell death in Hepa1c1c7 cells.Nana Asare et al.Mutagenesis, 24(6), 481-493 (2009-08-26) Mutagenicity of the phenolic microsomal metabolites of 3-nitrofluoranthene and 1-nitropyrene in strains of Salmonella typhimurium.M C Consolo et al.Mutation research, 210(2), 263-269 (1989-02-01) Voltammetric Determination of 3-Nitrofluoranthene and 3-Aminofluoranthene at Boron Doped Diamond Thin-Film Electrode.Cizek K, et al. Electroanalysis, 19(12), 1295-1299 (2007) Genetic toxicology and carcinogenicity of mono- and dinitrofluoranthenes.H Tokiwa et al.Mutation research, 297(2), 181-195 (1993-09-01) Metabolism of nitrofluoranthenes by rat lung subcellular fractions.C E Mitchell et al.Carcinogenesis, 14(6), 1161-1166 (1993-06-01) The use of silver solid amalgam electrodes for voltammetric and amperometric determination of nitrated polyaromatic compounds used as markers of incomplete combustion.Oksana Yosypchuk et al.TheScientificWorldJournal, 2012, 231986-231986 (2012-05-24)
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