Boiling point	88-90 ºC
Flash point	18 ºC
Density	1.335
Refractive index	1.4905

Symbol(GHS)	F;T
Hazard Codes	R11;R25;R36/37/38;R63
SDS/MSDS	S16;S26;S28A;S37/39;S45

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

More

Name	CAS

More

Articles

Peer-Reviewed Papers

Rapid and efficient synthesis of 4(3H)-quinazolinones under ultrasonic irradiation using silica-supported Preyssler nanoparticles.Majid M Heravi et al.Ultrasonics sonochemistry, 16(6), 708-710 (2009-04-14) [Chemical studies of Strobilanthes cusia].L Li et al.Yao xue xue bao = Acta pharmaceutica Sinica, 28(3), 238-240 (1993-01-01) Synthesis and in vitro antitumor activity of 4(3H)-quinazolinone derivatives with dithiocarbamate side chains.Sheng-Li Cao et al.Bioorganic & medicinal chemistry letters, 15(7), 1915-1917 (2005-03-23) Topoisomerase inhibitors induce apoptosis in thymocytes.Y Onishi et al.Biochimica et biophysica acta, 1175(2), 147-154 (1993-01-17) DFT studies of the structure and vibrational assignments of 4-hydroxy quinazoline and 2-hydroxy benzimidazole.V Krishnakumar et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 66(4-5), 1082-1090 (2006-07-28) Hexamethylenebisacetamide selectively inhibits the proliferation of human and rat vascular smooth-muscle cells.D J Grainger et al.The Biochemical journal, 283 ( Pt 2), 403-408 (1992-04-15) The 3D-QSAR analysis of 4(3H)-quinazolinone derivatives with dithiocarbamate side chains on thymidylate synthase.Shiying Liu et al.Bioorganic & medicinal chemistry, 14(5), 1425-1430 (2005-11-03) Critical role of PI3-kinase/Akt activation in the PARP inhibitor induced heart function recovery during ischemia-reperfusion.Krisztina Kovacs et al.Biochemical pharmacology, 71(4), 441-452 (2005-12-13) Effect of poly(ADP-ribose) polymerase inhibitors on the ischemia-reperfusion-induced oxidative cell damage and mitochondrial metabolism in Langendorff heart perfusion system.R Halmosi et al.Molecular pharmacology, 59(6), 1497-1505 (2001-05-17) Validation of a sensitive simultaneous LC-MS/MS method for the quantification of novel anti-cancer thiazolidinedione and quinazolin-4-one derivatives in rat plasma and its application in a rat pharmacokinetic study.Shankar Sengottuvelan et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1121, 18-27 (2019-05-15) Iduna protects HT22 cells by inhibiting parthanatos: The role of the p53-MDM2 pathway.Haoxiang Xu et al.Experimental cell research, 384(1), 111547-111547 (2019-09-01) Parallel solution phase synthesis of 3,6,7-4(3H)-quinazolinones and evaluation of their antitumor activities against human cancer.Hao Wu et al.Journal of combinatorial chemistry, 12(3), 346-355 (2010-03-04) Design, synthesis, and molecular docking studies of 2-(furan-2-yl)quinazolin-4-one derivatives as potential antiproliferative agents.Marwa F Ahmed et al.Archiv der Pharmazie, 348(7), 487-497 (2015-04-30) [Synthesis and in vitro antitumor activity of 4(3H)-quinazolinone derivatives bearing dithiocarbamate chains].Sheng-li Cao et al.Yao xue xue bao = Acta pharmaceutica Sinica, 42(7), 741-746 (2007-09-22) Synthesis and Biological Evaluation of Three New Chitosan Schiff Base Derivatives.Nadia Q Haj et al.ACS omega, 5(23), 13948-13954 (2020-06-23) 4(3H)-Quinazolone regulates innate immune signaling upon respiratory syncytial virus infection by moderately inhibiting the RIG-1 pathway in RAW264.7 cell.Liwei He et al.International immunopharmacology, 52, 245-252 (2017-09-29) Loss of the MYC gene amplified in human HL-60 cells after treatment with inhibitors of poly(ADP-ribose) polymerase or with dimethyl sulfoxide.H Shima et al.Proceedings of the National Academy of Sciences of the United States of America, 86(19), 7442-7445 (1989-10-01) The antihyperlipidemic activities of 4(3H) quinazolinone and two halogenated derivatives in rats.Fawzia M Refaie et al.Lipids in health and disease, 4, 22-22 (2005-10-06) Regulation of kinase cascades and transcription factors by a poly(ADP-ribose) polymerase-1 inhibitor, 4-hydroxyquinazoline, in lipopolysaccharide-induced inflammation in mice.Balazs Veres et al.The Journal of pharmacology and experimental therapeutics, 310(1), 247-255 (2004-03-05) Oxidative stress inhibits apoptosis in human lymphoma cells.Y J Lee et al.The Journal of biological chemistry, 274(28), 19792-19798 (1999-07-03) Studies on standardization of folium strobilanthis, radix strobilanthis and their preparations.L Li et al.Biomedical chromatography : BMC, 8(3), 145-147 (1994-05-01) Hydrogen peroxide inhibits activation, not activity, of cellular caspase-3 in vivo.Y J Lee et al.Free radical biology & medicine, 29(7), 684-692 (2000-10-18) Inhibition of oxidative stress produced by plasma membrane NADH oxidase delays low-potassium-induced apoptosis of cerebellar granule cells.Francisco Javier Martín-Romero et al.Journal of neurochemistry, 82(3), 705-715 (2002-08-03) Diorganotin(IV) complexes of biologically potent 4(3H)-quinazolinone derived Schiff bases: synthesis, spectroscopic characterization, DNA interaction studies and antimicrobial activity.Kollur Shiva Prasad et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 81(1), 276-282 (2011-07-12)

Remarks