Melting point	-113 ºC
Water Solubility	Insoluble
Boiling point	67-68 ºC
Flash point	-20 ºC
Density	0.841
Refractive index	1.437-1.439

Symbol(GHS)	F;Xn;N
Hazard Codes	R11;R21/22;R36/37/38;R50
SDS/MSDS	S16;S26;S29;S36/37/39;S57

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Articles

Peer-Reviewed Papers

Digestive enzymes and stylet morphology of Deraeocoris nigritulus (Uhler)(Hemiptera: Miridae) reflect adaptations for predatory habitsBoyd DW Annals of the Entomological Society of America, 96(5), 667-671 (2014) Biopolymers conjugated with magnetite as support materials for trypsin immobilization and protein digestion.Jakub Zdarta et al.Colloids and surfaces. B, Biointerfaces, 169, 118-125 (2018-05-15) Identification and partial characterization of midgut proteases in the lesser mulberry pyralid, Glyphodes pyloalis.Atiyeh Mahdavi et al.Journal of insect science (Online), 13, 81-81 (2013-11-16) Application and properties of butyl acrylate/pentaerythrite triacrylate copolymers and cellulose-based Granocel as carriers for trypsin immobilization.Jolanta Bryjak et al.Colloids and surfaces. B, Biointerfaces, 61(1), 66-74 (2007-09-05) Characterization of Treponema denticola mutants defective in the major antigenic proteins, Msp and TmpC.Yuki Abiko et al.PloS one, 9(11), e113565-e113565 (2014-11-18) Characterization of a Chitin-Binding Protein from Bacillus thuringiensis HD-1.Naresh Arora et al.PloS one, 8(6), e66603-e66603 (2013-07-05) Trypsin and N-aminopeptidase (APN) activities in the hepatopancreas of an intertidal euryhaline crab: Biochemical characteristics and differential modulation by histamine and salinity.Maria Soledad Michiels et al.Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 204, 228-235 (2016-12-08) Comparative analyses of exoproteinases produced by three phytopathogenic microorganisms.Tatiana A Valueva et al.Journal of pathogens, 2011, 947218-947218 (2011-01-01) Kinetic properties of three isoforms of trypsin isolated from the pyloric caeca of chum salmon (Oncorhynchus keta).Eiko Toyota et al.Biological & pharmaceutical bulletin, 30(9), 1648-1652 (2007-09-11) A new chymotrypsin-like serine protease involved in dietary protein digestion in a primitive animal, Scorpio maurus: purification and biochemical characterization.Hanen Louati et al.Lipids in health and disease, 10, 121-121 (2011-07-23) Cell penetrable, clickable and tagless activity-based probe of human cathepsin L.Dibyendu Dana et al.Bioorganic chemistry, 85, 505-514 (2019-02-26) Analysis of serine proteases from marine sponges by 2-D zymography.Jeff G Wilkesman et al.Electrophoresis, 28(3), 429-436 (2006-12-30) Porphyromonas gingivalis induce apoptosis in human gingival epithelial cells through a gingipain-dependent mechanism.Panagiota G Stathopoulou et al.BMC microbiology, 9, 107-107 (2009-05-29) Digestive proteinases of the larger black flour beetle, Cynaeus angustus (Coleoptera: Tenebrionidae).B Oppert et al.Bulletin of entomological research, 96(2), 167-172 (2006-03-25) A study on β-glucan binding protein (β-GBP) and its involvement in phenoloxidase cascade in Indian white shrimp Fenneropenaeus indicus.Mahalingam Anjugam et al.Molecular immunology, 92, 1-11 (2017-10-14) Impact of partial replacement of rice with other selected cereals on idli batter fermentation and idli characteristics.Monika Rani et al.Journal of food science and technology, 56(3), 1192-1201 (2019-04-09) Protein purification from Arachis hypogaea in one step: stability studies and anticarcinogenic analysis.Afaque Ahmad et al.Food science and biotechnology, 29(1), 35-43 (2020-01-25) Immobilization of trypsin in organic and aqueous media for enzymatic peptide synthesis and hydrolysis reactions.Julia Stolarow et al.BMC biotechnology, 15, 77-77 (2015-08-20) Intensity fading MALDI-TOF mass spectrometry and functional proteomics assignments to identify protease inhibitors in marine invertebrates.Giovanni Covaleda et al.Journal of proteomics, 165, 75-92 (2017-06-13) Relationship between Glycation and Polyphenol Content and the Bioactivity of Selected Commercial Soy Milks.M Carmen Arques et al.Journal of agricultural and food chemistry, 64(8), 1823-1830 (2016-02-16) Effect of PEG molecular weight and linking chemistry on the biological activity and thermal stability of PEGylated trypsin.Benjaporn Treetharnmathurot et al.International journal of pharmaceutics, 357(1-2), 252-259 (2008-03-01) Improvement of the enzyme performance of trypsin via adsorption in mesoporous silica SBA-15: hydrolysis of BAPNA.Shanshan Li et al.Molecules (Basel, Switzerland), 18(1), 1138-1149 (2013-01-18) Gingipain of Porphyromonas gingivalis manipulates M1 macrophage polarization through C5a pathway.Yubo Hou et al.In vitro cellular & developmental biology. Animal, 53(7), 593-603 (2017-06-22) Specificity studies on proteases for dehairing in leather processing using decorin as model conjugated protein.S Shakilanishi et al.International journal of biological macromolecules, 103, 1069-1076 (2017-05-31) Bioactive properties of peptides obtained from Argentinian defatted soy flour protein by Corolase PP hydrolysis.Ezequiel R Coscueta et al.Food chemistry, 198, 36-44 (2016-01-16) High-yield secretory production of stable, active trypsin through engineering of the N-terminal peptide and self-degradation sites in Pichia pastoris.Yunfeng Zhang et al.Bioresource technology, 247, 81-87 (2017-09-26) Deletion of lipoprotein PG0717 in Porphyromonas gingivalis W83 reduces gingipain activity and alters trafficking in and response by host cells.Leticia Reyes et al.PloS one, 8(9), e74230-e74230 (2013-09-27) Electrostatic assisted fabrication and dissociation of multi-component proteinosomes.Yaqian Cai et al.Journal of colloid and interface science, 576, 90-98 (2020-05-15) Understanding the binding interaction between methotrexate and human alpha-2-macroglobulin: Multi-spectroscopic and computational investigation.Mohammad Khalid Zia et al.Archives of biochemistry and biophysics, 675, 108118-108118 (2019-10-02) Inactivation of Alpha-2-Macroglobulin by Photo-Illuminated Gallic Acid.Tooba Siddiqui et al.Journal of fluorescence, 29(4), 969-979 (2019-07-22) Deletion of a conserved transcript PG_RS02100 expressed during logarithmic growth in Porphyromonas gingivalis results in hyperpigmentation and increased tolerance to oxidative stress.Priscilla L Phillips et al.PloS one, 13(11), e0207295-e0207295 (2018-11-13) Preventive effect of phytic acid on lysosomal hydrolases in normal and isoproterenol-induced myocardial infarction in Wistar rats.E Brindha et al.Toxicology mechanisms and methods, 25(2), 150-154 (2015-01-07) Biochemical characterization and in vitro biological activities of the epithelial cell extracts from Hypanus dipterurus spine.Estrella Marrón-Grijalba et al.Toxicon : official journal of the International Society on Toxinology, 187, 129-135 (2020-09-12) Design, synthesis, evaluation and thermodynamics of 1-substituted pyridylimidazo[1,5-a]pyridine derivatives as cysteine protease inhibitors.Mohd Sajid Khan et al.PloS one, 8(8), e69982-e69982 (2013-08-14) Modification of mouse A2M B (620-792) and A2M N (168-230) by malondialdehyde and acetaldehyde attenuates the proteinase and TGF-β1 binding ability of A2MB.Inderjeet Kaur et al.FEBS letters, 585(6), 829-833 (2011-02-16) Trypsin inhibitors demonstrate antioxidant activities, inhibit A549 cell proliferation, and increase activities of reactive oxygen species scavenging enzymes.Tooba Naz Shamsi et al.Indian journal of pharmacology, 49(2), 155-160 (2017-07-15) Effects of inter-alpha inhibitor proteins on neonatal brain injury: Age, task and treatment dependent neurobehavioral outcomes.Steven W Threlkeld et al.Experimental neurology, 261, 424-433 (2014-08-02) Quality, protease inhibitor and gelling property of duck egg albumen as affected by storage conditions.Tran Hong Quan et al.Journal of food science and technology, 55(2), 513-522 (2018-02-03) Carrier free immobilization and characterization of trypsin.Esra Menfaatli et al.Artificial cells, nanomedicine, and biotechnology, 43(2), 140-144 (2013-11-08) Searching for tryptase in the RBL-2H3 mast cell model: Preparation for comparative mast cell toxicology studies with zebrafish.Juyoung K Shim et al.Journal of applied toxicology : JAT, 39(3), 473-484 (2018-10-31) Rational design and characterization of D-Phe-Pro-D-Arg-derived direct thrombin inhibitors.Ana C Figueiredo et al.PloS one, 7(3), e34354-e34354 (2012-03-30) Localization of trypsin-like protease in postmortem tissue of white shrimp (Litopenaeus vannamei) and its effect in muscle softening.Yuanhuai Peng et al.Food chemistry, 290, 277-285 (2019-04-20) A chymotrypsin from the Digestive Tract of California Spiny Lobster, Panulirus interruptus: Purification and Biochemical Characterization.Betsaida Bibo-Verdugo et al.Marine biotechnology (New York, N.Y.), 17(4), 416-427 (2015-04-17) Inhibitory effects of the recombinant human serine protease inhibitor Hespintor on the proliferation, migration and invasion of hepatocellular carcinoma cells.Xue-Lei Wang et al.Oncology reports, 33(2), 729-736 (2014-12-17) Factors affecting the anthelmintic efficacy of papaya latex in vivo: host sex and intensity of infection.Wenceslaus Luoga et al.Parasitology research, 114(7), 2535-2541 (2015-04-10) Inactivation of Soybean Bowman-Birk Inhibitor by Stevioside: Interaction Studies and Application to Soymilk.Chun Liu et al.Journal of agricultural and food chemistry, 67(8), 2255-2264 (2019-02-08) Structural analysis of the meiosis-related protein MS5 reveals non-canonical papain enhancement by cystatin-like folds.Xiang Wang et al.FEBS letters, 594(15), 2462-2471 (2020-05-18) The anthelmintic efficacy of natural plant cysteine proteinases against Hymenolepis microstoma in vivo.F Mansur et al.Journal of helminthology, 89(5), 601-611 (2014-09-17) Peptide splicing in a double-sequence analogue of trypsin inhibitor SFTI-1 substituted in the P₁ positions by peptoid monomers.Natalia Karna et al.Biopolymers, 104(3), 206-212 (2015-04-24) Faecal leukocyte esterase activity is an alternative biomarker in inflammatory bowel disease.Els N Dumoulin et al.Clinical chemistry and laboratory medicine, 53(12), 2003-2008 (2015-04-18) Nano-eco toxicity study of gold nanoparticles on aquatic organism Moina macrocopa: As new versatile ecotoxicity testing model.Hemant P Borase et al.Environmental toxicology and pharmacology, 68, 4-12 (2019-03-09) Overexpression and mechanistic characterization of blastula protease 10, a metalloprotease involved in sea urchin embryogenesis and development.Giordano F Z da Silva et al.The Journal of biological chemistry, 281(16), 10737-10744 (2006-02-24) A new Piper nigrum cysteine proteinase inhibitor, PnCPI, with antifungal activity: molecular cloning, recombinant expression, functional analyses and molecular modeling.Aline Medeiros Lima et al.Planta, 252(2), 16-16 (2020-07-15) Nafamostat mesilate, a potent tryptase inhibitor, modulates periodontitis in rats.Marinella Holzhausen et al.Clinical oral investigations, 15(6), 967-973 (2010-09-08) Evidence for Ancient Origins of Bowman-Birk Inhibitors fromAmy M James et al.The Plant cell, 29(3), 461-473 (2017-03-17) A salt-bridge stabilized C-terminal hook is critical for the dimerization of a Bowman Birk inhibitor.Vinod Kumar et al.Archives of biochemistry and biophysics, 566, 15-25 (2014-12-21) A chitin-binding lectin from Moringa oleifera seeds (WSMoL) impairs the digestive physiology of the Mediterranean flour larvae, Anagasta kuehniella.Caio Fernando Ramalho de Oliveira et al.Pesticide biochemistry and physiology, 142, 67-76 (2017-11-07) Structural and functional relationship of Cassia obtusifolia trypsin inhibitor to understand its digestive resistance against Pieris rapae.Jiayu Zhou et al.International journal of biological macromolecules, 148, 908-920 (2020-01-26) Role of trypsin and protease-activated receptor-2 in ovarian cancer.Kyu Kwang Kim et al.PloS one, 15(5), e0232253-e0232253 (2020-05-05) Oxidation-resistant and thermostable forms of alpha-1 antitrypsin from Escherichia coli inclusion bodies.Wei Zhu et al.FEBS open bio, 8(10), 1711-1721 (2018-10-20) Characterization of binding interactions between selected phenylpropanoid glycosides and trypsin.Yue Feng et al.Food chemistry, 243, 118-124 (2017-11-18) Comparative analysis of nutritional quality of five different cultivars of sweet potatoes (Ipomea batatas (L) Lam) in Sri Lanka.Suraji A Senanayake et al.Food science & nutrition, 1(4), 284-291 (2014-05-08) Evaluation of nutritional quality and antioxidant potential of pigeonpea genotypes.Japjot Sekhon et al.Journal of food science and technology, 54(11), 3598-3611 (2017-10-21) Two novel S1 peptidases from Amycolatopsis keratinophila subsp. keratinophila D2T degrading keratinous slaughterhouse by-products.Roall Espersen et al.Applied microbiology and biotechnology, 104(6), 2513-2522 (2020-01-29) New APETx-like peptides from sea anemone Heteractis crispa modulate ASIC1a channels.Rimma Kalina et al.Peptides, 104, 41-49 (2018-04-24) Isolation and characterization of a trypsin fraction from the pyloric ceca of chinook salmon (Oncorhynchus tshawytscha).I Kurtovic et al.Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 143(4), 432-440 (2006-02-07) Purification and characterization of a novel trypsin-like protease from green-seeded chickpea (Cicer arientum).Tooba Naz Shamsi et al.Preparative biochemistry & biotechnology, 47(5), 513-519 (2017-03-10) Biophysical insight into structure-function relation of Allium sativum Protease Inhibitor by thermal, chemical and pH-induced modulation using comprehensive spectroscopic analysis.Tooba Naz Shamsi et al.International journal of biological macromolecules, 103, 415-423 (2017-05-22) Effects of a commercial probiotic BS containing Bacillus subtilis and Bacillus licheniformis on growth, immune response and disease resistance in Nile tilapia, Oreochromis niloticus.Emmanuel Delwin Abarike et al.Fish & shellfish immunology, 82, 229-238 (2018-08-21) Role of purified β-1, 3 glucan binding protein (β-GBP) from Paratelphusa hydrodromus and their anti-inflammatory, antioxidant and antibiofilm properties.Arokiadhas Iswarya et al.Fish & shellfish immunology, 68, 54-64 (2017-07-08) A triple stranded G-quadruplex formation in the promoter region of human myosin β(Myh7) gene.Anju Singh et al.Journal of biomolecular structure & dynamics, 1-14 (2017-09-21) Comparative analysis of motility and other properties of Treponema denticola strains.Keiji Nagano et al.Microbial pathogenesis, 102, 82-88 (2016-12-05) The melatonin receptor antagonist luzindole induces Ca2+ mobilization, reactive oxygen species generation and impairs trypsin secretion in mouse pancreatic acinar cells.Matias Estaras et al.Biochimica et biophysica acta. General subjects, 1863(11), 129407-129407 (2019-08-06) Biochemical characterization of a Kunitz inhibitor from Inga edulis seeds with antifungal activity against Candida spp.Heloisa Xavier Dib et al.Archives of microbiology, 201(2), 223-233 (2018-11-30) Heterologous expression of a cryptic gene cluster from Grimontia marina affords a novel tricyclic peptide grimoviridin.Kohta Unno et al.Applied microbiology and biotechnology, 104(12), 5293-5302 (2020-04-18) Cysteine Protease Inhibitors Reduce Enzymatic Browning of Potato by Lowering the Accumulation of Free Amino Acids.Tiantian Dong et al.Journal of agricultural and food chemistry, 68(8), 2467-2476 (2020-02-08) Shared strategies for β-lactam catabolism in the soil microbiome.Terence S Crofts et al.Nature chemical biology, 14(6), 556-564 (2018-05-02) Identification of a new alpha-2-macroglobulin: Multi-spectroscopic and isothermal titration calorimetry study.Ahmed Abdur Rehman et al.International journal of biological macromolecules, 83, 366-375 (2015-11-27) Partial purification and characterization of trypsin-like proteinases from insecticide-resistant and -susceptible strains of the maize weevil, Sitophilus zeamais.L B Silva et al.Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 155(1), 12-19 (2009-10-20) Gut immune functions and health in Atlantic salmon (Salmo salar) from late freshwater stage until one year in seawater and effects of functional ingredients: A case study from a commercial sized research site in the Arctic region.Jie Wang et al.Fish & shellfish immunology, 106, 1106-1119 (2020-09-18) Serine protease inhibitors from squid ovary: extraction and its effect on proteolysis and gel properties of surimi.Avtar Singh et al.Journal of food science and technology, 54(1), 267-275 (2017-03-01) The effect of thermal treatment of whole soybean flour on the conversion of isoflavones and inactivation of trypsin inhibitors.J C Andrade et al.Food chemistry, 194, 1095-1101 (2015-10-17) Influence of dietary zinc and copper on digestive enzyme activity and intestinal morphology in weaned pigs.Hedemann MS Journal of Animal Science, 84(12), 3310-3320 (2006) Proteolysis is a confounding factor in the interpretation of faecal calprotectin.Els N Dumoulin et al.Clinical chemistry and laboratory medicine, 53(1), 65-71 (2014-07-06) Serine protease inhibitor Kazal-type 2 is expressed in the male reproductive tract of carp with a possible role in antimicrobial protection.Mariola A Dietrich et al.Fish & shellfish immunology, 60, 150-163 (2016-11-22) Trypsin from the viscera of Bogue (Boops boops): isolation and characterisation.Ahmed Barkia et al.Fish physiology and biochemistry, 36(4), 893-902 (2009-11-10) Golden gate shuffling: a one-pot DNA shuffling method based on type IIs restriction enzymes.Carola Engler et al.PloS one, 4(5), e5553-e5553 (2009-05-14) Protease activity increases in plasma, peritoneal fluid, and vital organs after hemorrhagic shock in rats.Angelina E Altshuler et al.PloS one, 7(3), e32672-e32672 (2012-04-06) Picoliter enzyme reactor on a nanofluidic device exceeding the bulk reaction rate.Koki Yamamoto et al.The Analyst, 145(17), 5801-5807 (2020-07-22) Povidone-iodine used as an adjunct to non-surgical treatment of furcation involvements.Erica Del Peloso Ribeiro et al.Journal of periodontology, 77(2), 211-217 (2006-02-08) The effect of thermal treatment of whole soybean flour on the conversion of isoflavones and inactivation of trypsin inhibitors.J C Andrade et al.Food chemistry, 194, 1095-1101 (2015-10-17) Toxic compound, anti-nutritional factors and functional properties of protein isolated from detoxified Jatropha curcas seed cake.Donlaporn Saetae et al.International journal of molecular sciences, 12(1), 66-77 (2011-02-23) Periodontal debridement with povidone-iodine in periodontal treatment: short-term clinical and biochemical observations.Guilherme M Zanatta et al.Journal of periodontology, 77(3), 498-505 (2006-03-04) Effects of a commercial probiotic BS containing Bacillus subtilis and Bacillus licheniformis on growth, immune response and disease resistance in Nile tilapia, Oreochromis niloticus.Emmanuel Delwin Abarike et al.Fish & shellfish immunology, 82, 229-238 (2018-08-21) Purification and characterization of Bowman-Birk and Kunitz isoinhibitors from the seeds of Rhynchosia sublobata (Schumach.) Meikle, a wild relative of pigeonpea.Soundappan S Mohanraj et al.Phytochemistry, 159, 159-171 (2019-01-12) A tumor vessel-targeting fusion protein elicits a chemotherapeutic bystander effect in pancreatic ductal adenocarcinoma.Chun-Te Chen et al.American journal of cancer research, 7(3), 657-672 (2017-04-13) Proteolysis is a confounding factor in the interpretation of faecal calprotectin.Els N Dumoulin et al.Clinical chemistry and laboratory medicine, 53(1), 65-71 (2014-07-06) Trypsin from the viscera of Bogue (Boops boops): isolation and characterisation.Ahmed Barkia et al.Fish physiology and biochemistry, 36(4), 893-902 (2009-11-10) Golden gate shuffling: a one-pot DNA shuffling method based on type IIs restriction enzymes.Carola Engler et al.PloS one, 4(5), e5553-e5553 (2009-05-14) Ecotin: Exploring a feasible antithrombotic profile.Luciana Serrão Wermelinger et al.International journal of biological macromolecules, 78, 296-303 (2015-04-18) Chemically modified alginate bead matrix for efficient adsorptive recovery of trypsin from fresh bovine pancreas.Pilar Aravena et al.Biotechnology progress, 34(5), 1269-1277 (2018-10-04) Insight into the inactivation mechanism of soybean Bowman-Birk trypsin inhibitor (BBTI) induced by epigallocatechin gallate and epigallocatechin: Fluorescence, thermodynamics and docking studies.Zhongqin Chen et al.Food chemistry, 303, 125380-125380 (2019-08-25) Differences in survival, virulence and biofilm formation between sialidase-deficient and W83 wild-type Porphyromonas gingivalis strains under stressful environmental conditions.Xiaoyu Xu et al.BMC microbiology, 17(1), 178-178 (2017-08-20) Magnetically modified bacterial cellulose: A promising carrier for immobilization of affinity ligands, enzymes, and cells.Eva Baldikova et al.Materials science & engineering. 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