Water Solubility	soluble
Boiling point	132-133 ºC
Flash point	33 ºC
Density	0.88
Refractive index	1.461-1.463

Symbol(GHS)	Xi
Hazard Codes	R10;R36/37/38
SDS/MSDS	S16;S26;S37/39

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Identification of urinary metabolites of the red clover isoflavones formononetin and biochanin A in human subjects.Satu-Maarit Heinonen et al.Journal of agricultural and food chemistry, 52(22), 6802-6809 (2004-10-28) The dietary isoflavone biochanin-A sensitizes prostate cancer cells to TRAIL-induced apoptosis.Ewelina Szliszka et al.Urologic oncology, 31(3), 331-342 (2011-08-02) LC-ESI-MS characterisation of phytoalexins induced in chickpea and pea tissues in response to a biotic elicitor of Hypnea musciformis (red algae).Muhammad Arman Natural product research, 25(14), 1352-1360 (2011-08-24) [Establishment and application of co-transfection screening method for phytoestrogen active constituents].Huabo Wei et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(18), 2530-2534 (2012-01-20) Differential antiviral and anti-inflammatory mechanisms of the flavonoids biochanin A and baicalein in H5N1 influenza A virus-infected cells.Patchima Sithisarn et al.Antiviral research, 97(1), 41-48 (2012-10-27) Effects of phytoestrogens derived from soy bean on expression of adhesion molecules on HUVEC.C M de Andrade et al.Climacteric : the journal of the International Menopause Society, 15(2), 186-194 (2011-11-10) Combination of Biochanin A and Temozolomide Impairs Tumor Growth by Modulating Cell Metabolism in Glioblastoma MultiformeDesai V, et al. Anticancer research, 39(1), 57-66 (2019) Improved effectiveness of biochanin A as a P-gp inhibitor in solid dispersion.Hyo-Kyung Han et al.Die Pharmazie, 66(9), 710-715 (2011-10-27) Biochanin A ameliorates the cytokine secretion profile of lipopolysaccharide-stimulated macrophages by a PPARγ-dependent pathway.Longxin Qiu et al.Molecular medicine reports, 5(1), 217-222 (2011-09-29) Inhibition of matrix degrading enzymes and invasion in human glioblastoma (U87MG) cells by isoflavones.Shilpa Puli et al.Journal of neuro-oncology, 79(2), 135-142 (2006-04-07) The sulfated conjugate of biochanin A is a substrate of breast cancer resistant protein (ABCG2).Guohua An et al.Biopharmaceutics & drug disposition, 32(8), 446-457 (2011-09-13) Red clover extract ameliorates dyslipidemia in streptozotocin-induced diabetic C57BL/6 mice by activating hepatic PPARα.Longxin Qiu et al.Phytotherapy research : PTR, 26(6), 860-864 (2011-11-16) Absorption of red clover isoflavones in human subjects: results from a pilot study.Ronald Maul et al.The British journal of nutrition, 103(11), 1569-1572 (2010-01-14) Ester and carbamate ester derivatives of Biochanin A: synthesis and in vitro evaluation of estrogenic and antiproliferative activities.Nikolas Fokialakis et al.Bioorganic & medicinal chemistry, 20(9), 2962-2970 (2012-04-03) A new strategy to modulate alopecia using a combination of two specific and unique ingredients.Estelle Loing et al.Journal of cosmetic science, 64(1), 45-58 (2013-03-02) Attenuation of mitogen- and stress-activated protein kinase-1-driven nuclear factor-kappaB gene expression by soy isoflavones does not require estrogenic activity.Wim Vanden Berghe et al.Cancer research, 66(9), 4852-4862 (2006-05-03) Antihyperglycemic effect of biochanin A, a soy isoflavone, on streptozotocin-diabetic rats.Ranganathan Harini et al.European journal of pharmacology, 676(1-3), 89-94 (2011-12-20) The sulfated conjugate of biochanin A is a substrate of breast cancer resistant protein (ABCG2).Guohua An et al.Biopharmaceutics & drug disposition, 32(8), 446-457 (2011-09-13) The dietary isoflavone biochanin-A sensitizes prostate cancer cells to TRAIL-induced apoptosis.Ewelina Szliszka et al.Urologic oncology, 31(3), 331-342 (2011-08-02) Two novel phenolic compounds from the rhizomes of Cyperus rotundus L.Zhongliu Zhou et al.Molecules (Basel, Switzerland), 17(11), 12636-12641 (2012-10-27) Apoptotic effects of genistein, biochanin-A and apigenin on LNCaP and PC-3 cells by p21 through transcriptional inhibition of polo-like kinase-1.Young Jin Seo et al.Journal of Korean medical science, 26(11), 1489-1494 (2011-11-09) Identification of Genistein and Biochanin A by THz (far-infrared) vibrational spectra.Yuping Yang et al.Journal of pharmaceutical and biomedical analysis, 62, 177-181 (2012-01-17) Liquid chromatography-mass spectrometry method for the quantification of tamoxifen and its metabolite 4-hydroxytamoxifen in rat plasma: application to interaction study with biochanin A (an isoflavone).Sheelendra Pratap Singh et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(27), 2845-2851 (2011-09-06) Germination dramatically increases isoflavonoid content and diversity in chickpea (Cicer arietinum L.) seeds.Ziyun Wu et al.Journal of agricultural and food chemistry, 60(35), 8606-8615 (2012-07-24) Distribution of isoflavones and coumestrol in neglected tropical and subtropical legumes.Olga Leuner et al.Journal of the science of food and agriculture, 93(3), 575-579 (2012-08-29) MLK3 is a direct target of biochanin A, which plays a role in solar UV-induced COX-2 expression in human keratinocytes.Tae-Gyu Lim et al.Biochemical pharmacology, 86(7), 896-903 (2013-08-21) Effects of sodium metavanadate and germination on the sprouting of chickpeas and its content of vanadium, formononetin and biochanin A in the sprouts.Ling Zhang et al.Journal of dietary supplements, 9(1), 34-44 (2012-03-22) Double-edged sword effect of biochanin to inhibit nuclear factor kappaB: suppression of serine/threonine and tyrosine kinases.Sunil Kumar Manna Biochemical pharmacology, 83(10), 1383-1392 (2012-03-06) Neuroprotective effects of biochanin A against glutamate-induced cytotoxicity in PC12 cells via apoptosis inhibition.Ji Wei Tan et al.Neurochemical research, 38(3), 512-518 (2012-12-12) Reduced bioavailability of tamoxifen and its metabolite 4-hydroxytamoxifen after oral administration with biochanin A (an isoflavone) in rats.Sheelendra Pratap Singh et al.Phytotherapy research : PTR, 26(2), 303-307 (2011-12-02) Estrogenic effect of the phytoestrogen biochanin A in zebrafish, Danio rerio, and brown trout, Salmo truttaHolbech H, et al. Aquatic Toxicology (Amsterdam, Netherlands), 144, 19-25 (2013) Membrane dipole modifiers modulate single-length nystatin channels via reducing elastic stress in the vicinity of the lipid mouth of a pore.Evgeny G Chulkov et al.Biochimica et biophysica acta, 1848(1 Pt A), 192-199 (2014-09-17) Absorption of red clover isoflavones in human subjects: results from a pilot study.Ronald Maul et al.The British journal of nutrition, 103(11), 1569-1572 (2010-01-14) Ester and carbamate ester derivatives of Biochanin A: synthesis and in vitro evaluation of estrogenic and antiproliferative activities.Nikolas Fokialakis et al.Bioorganic & medicinal chemistry, 20(9), 2962-2970 (2012-04-03) A new strategy to modulate alopecia using a combination of two specific and unique ingredients.Estelle Loing et al.Journal of cosmetic science, 64(1), 45-58 (2013-03-02) Attenuation of mitogen- and stress-activated protein kinase-1-driven nuclear factor-kappaB gene expression by soy isoflavones does not require estrogenic activity.Wim Vanden Berghe et al.Cancer research, 66(9), 4852-4862 (2006-05-03) Antihyperglycemic effect of biochanin A, a soy isoflavone, on streptozotocin-diabetic rats.Ranganathan Harini et al.European journal of pharmacology, 676(1-3), 89-94 (2011-12-20)

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