Melting point	-73.1 ºC
Water Solubility	react
Boiling point	140 ºC
Flash point	54 ºC
Density	1.087
Refractive index	1.389-1.391

Symbol(GHS)	C
Hazard Codes	R10;R20/21;R34
SDS/MSDS	S26;S36/37/39;S45

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Articles

Peer-Reviewed Papers

Toxicity of lupane derivatives on anionic membrane models, isolated rat mitochondria and selected human cell lines: Role of terminal alkyl chains.Filipa S Carvalho et al.Chemico-biological interactions, 296, 198-210 (2018-10-08) Stereospecificity of enzyme induction by 2-phenylpropionic acid.S Fournel et al.Pharmacology & therapeutics, 33(1), 79-82 (1987-01-01) Involvement of arginine 120, glutamate 524, and tyrosine 355 in the binding of arachidonate and 2-phenylpropionic acid inhibitors to the cyclooxygenase active site of ovine prostaglandin endoperoxide H synthase-1.D K Bhattacharyya et al.The Journal of biological chemistry, 271(4), 2179-2184 (1996-01-26) Substrate specificity and enantioselectivity of arylcarboxylic acid glucuronidation.S Fournel-Gigleux et al.Drug metabolism and disposition: the biological fate of chemicals, 16(4), 627-634 (1988-07-01) Dummy-surface molecularly imprinted polymers as a sorbent of micro-solid-phase extraction combined with dispersive liquid-liquid microextraction for determination of five 2-phenylpropionic acid NSAIDs in aquatic environmental samples.Ping Guo et al.Analytical and bioanalytical chemistry, 410(2), 373-389 (2017-11-11) Serum and fecal profiles of aromatic microbial metabolites reflect gut microbiota disruption in critically ill patients: a prospective observational pilot study.Ekaterina Chernevskaya et al.Critical care (London, England), 24(1), 312-312 (2020-06-10) 2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors.Marcello Allegretti et al.Journal of medicinal chemistry, 48(13), 4312-4331 (2005-06-25) Stereoselective metabolism of 2-phenylpropionic acid in rat. II. Studies on the organs responsible for the optical isomerization of 2-phenylpropionic acid in rat in vivo.T Yamaguchi et al.Drug metabolism and disposition: the biological fate of chemicals, 15(4), 535-539 (1987-07-01) Stereoselective and domain-specific effects of ibuprofen on the thermal stability of human serum albumin.Alexa Guglielmelli et al.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 112, 122-131 (2017-11-22) Chemistry around imidazopyrazine and ibuprofen: discovery of novel fatty acid amide hydrolase (FAAH) inhibitors.Frédéric De Wael et al.European journal of medicinal chemistry, 45(9), 3564-3574 (2010-06-24) Stereoselective internal acyl migration of 1beta-O-acyl glucuronides of enantiomeric 2-phenylpropionic acids.K Akira et al.Biological & pharmaceutical bulletin, 23(4), 506-510 (2000-04-28) Structural insights into the ene-reductase synthesis of profens.J Waller et al.Organic & biomolecular chemistry, 15(20), 4440-4448 (2017-05-10) Loading-washout studies of the stereoselective sinusoidal uptake of (R)- and (s)-2-phenylpropionyl acyl glucuronide.David M Shackleford et al.Current drug metabolism, 7(7), 817-826 (2006-11-01) Concentration-dependent effects of sodium cholate and deoxycholate bile salts on breast cancer cells proliferation and survival.Yamila B Gándola et al.Molecular biology reports, 47(5), 3521-3539 (2020-04-17) Recombinant expression and characterisation of the oxygen-sensitive 2-enoate reductase from Clostridium sporogenes.Pawel M Mordaka et al.Microbiology (Reading, England), 164(2), 122-132 (2017-11-08) Studies on the chemical reactivity of 2-phenylpropionic acid 1-O-acyl glucuronide and S-acyl-CoA thioester metabolites.Chunze Li et al.Chemical research in toxicology, 15(10), 1309-1317 (2002-10-22) Stereoisomeric profiling of chiral pharmaceutically active compounds in wastewaters and the receiving environment - A catchment-scale and a laboratory study.Dolores Camacho-Muñoz et al.Environment international, 127, 558-572 (2019-04-15) A chiral separation strategy for acidic drugs in capillary electrochromatography using both chlorinated and nonchlorinated polysaccharide-based selectors.Dima Albals et al.Electrophoresis, 35(19), 2807-2818 (2014-07-02) Synthesis of a poly(diphenylacetylene) bearing optically active anilide pendants and its application to a chiral stationary phase for high-performance liquid chromatography.Mai Nozaki et al.Journal of chromatography. A, 1622, 461173-461173 (2020-05-27) A mechanistic investigation of the microbial chiral inversion of 2-phenylpropionic acid by Verticillium lecanii.M J Thomason et al.Chirality, 9(3), 254-260 (1997-01-01) Application of thin-layer chromatography to investigate oscillatory instability of the selected profen enantiomers in dichloromethane.M Sajewicz et al.Journal of chromatographic science, 43(10), 542-548 (2006-01-28) Antioxidant and Antiinflammatory Compounds in Nutmeg (Myristicafragrans) Pericarp as Determined by in vitro Assays.Chuan-rui Zhang et al.Natural product communications, 10(8), 1399-1402 (2015-10-06) Lack of stereoselectivity of the peroxisome proliferation induced by 2-phenylpropionic acid: evidence against a role for lipid disturbance in peroxisome proliferation.D Ahmad et al.Chirality, 6(5), 365-371 (1994-01-01) Production of S-(+)-2-phenylpropionic acid from (R,S)-2-phenylpropionitrile by the combination of nitrile hydratase and stereoselective amidase in Rhodococcus equi TG328.T Gilligan et al.Applied microbiology and biotechnology, 39(6), 720-725 (1993-08-01) Stereoselective metabolism of 2-phenylpropionic acid in rat. I. In vitro studies on the stereoselective isomerization and glucuronidation of 2-phenylpropionic acid.Y Nakamura et al.Drug metabolism and disposition: the biological fate of chemicals, 15(4), 529-534 (1987-07-01) Evaluation of three temperature- and mobile phase-dependent retention models for reversed-phase liquid chromatographic retention and apparent retention enthalpy.Anthony R Horner et al.Journal of chromatography. A, 1589, 73-82 (2019-01-11) A loop structure allows TAPBPR to exert its dual function as MHC I chaperone and peptide editor.Lina Sagert et al.eLife, 9 (2020-03-14) Pharmacological Profile and Molecular Modeling of Cyclic Opioid Analogues Incorporating Various Phenylalanine Derivatives.Anna Adamska-Bartłomiejczyk et al.ChemMedChem, 15(14), 1322-1329 (2020-05-16) Endogenous salicylic acid accumulation is required for chilling tolerance in cucumber (Cucumis sativus L.) seedlings.Chun-Juan Dong et al.Planta, 240(4), 687-700 (2014-07-19) Optimization of the chiral inversion of 2-phenylpropionic acid by Verticillium lecanii.M J Thomason et al.The Journal of pharmacy and pharmacology, 49(3), 263-269 (1997-03-01) In vivo mechanistic studies on the metabolic activation of 2-phenylpropionic acid in rat.Chunze Li et al.The Journal of pharmacology and experimental therapeutics, 305(1), 250-256 (2003-03-22) Differential effects of fibrates on the metabolic activation of 2-phenylpropionic acid in rats.Chunze Li et al.Drug metabolism and disposition: the biological fate of chemicals, 36(4), 682-687 (2008-01-12) Application and comparison of high performance liquid chromatography and high speed counter-current chromatography in enantioseparation of (±)-2-phenylpropionic acid.Shengqiang Tong et al.Journal of chromatography. A, 1281, 79-86 (2013-02-20) Cytotoxicity of the mycotoxins deoxynivalenol and ochratoxin A on Caco-2 cell line in presence of resveratrol.G Cano-Sancho et al.Toxicology in vitro : an international journal published in association with BIBRA, 29(7), 1639-1646 (2015-06-24) Dissipation kinetic studies of fenamidone and propamocarb in vegetables under greenhouse conditions using liquid and gas chromatography coupled to high-resolution mass spectrometry.Rosalía López-Ruiz et al.Chemosphere, 226, 36-46 (2019-03-27) Enantioselective covalent binding of 2-phenylpropionic Acid to protein in vitro in rat hepatocytes.Chunze Li et al.Chemical research in toxicology, 15(11), 1480-1487 (2002-11-20) [Stereoselective chronopharmacokinetics of hydratropic acid in rats].Y S He et al.Yao xue xue bao = Acta pharmaceutica Sinica, 28(12), 893-898 (1993-01-01) Thermoresponsive chiral stationary phase functionalized with the copolymer of β-cyclodextrin and N-isopropylacrylamide for high performance liquid chromatography.Xiujun Ren et al.Journal of chromatography. A, 1618, 460904-460904 (2020-01-30) Stereoselective hepatic disposition of model diastereomeric acyl glucuronides.David M Shackleford et al.Journal of pharmacokinetics and pharmacodynamics, 31(1), 1-27 (2004-09-07) Simultaneous enantiomeric analysis of pharmacologically active compounds in environmental samples by chiral LC-MS/MS with a macrocyclic antibiotic stationary phase.Dolores Camacho-Muñoz et al.Journal of mass spectrometry : JMS, 52(2), 94-108 (2017-01-07) Formation of glycine conjugate and (-)-(R)-enantiomer from (+)-(S)-2-phenylpropionic acid suggesting the formation of the CoA thioester intermediate of (+)-(S)-enantiomer in dogs.Y Tanaka et al.Chirality, 4(6), 342-348 (1992-01-01) Hydrogels of dextran containing nonsteroidal anti-inflammatory drugs as pendant agents.Michelle Feeney et al.Drug delivery, 14(2), 87-93 (2007-03-17) Activation of TLR3 promotes the degeneration of retinal ganglion cells by upregulating the protein levels of JNK3.Shravan K Chintala et al.Investigative ophthalmology & visual science, 56(1), 505-514 (2015-01-08) Chiral carboxylic acids and their effects on melting-point behaviour in co-crystals with isonicotinamide.Andreas Lemmerer et al.Acta crystallographica. Section B, Structural science, 64(Pt 6), 780-790 (2008-11-26) Microbial metabolism of 2-arylpropionic acids: chiral inversion of ibuprofen and 2-phenylpropionic acid.A J Hutt et al.Chirality, 5(8), 596-601 (1993-01-01) 1-(5-Dimethylamino-1-naphthalenesulphonyl)-(S)-3-aminopyrrolidine (DNS-Apy) as a fluorescence chiral labelling reagent for carboxylic acid enantiomers.S al-Kindy et al.Biomedical chromatography : BMC, 11(3), 137-142 (1997-05-01) [The stereoselectivity of chrono-pharmacokinetic parameters of hydratropic acid in rats].Y S He et al.Yao xue xue bao = Acta pharmaceutica Sinica, 28(11), 817-822 (1993-01-01)

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