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Peer-Reviewed Papers

Associations of genetic lactase non-persistence and sex with bone loss in young adulthood.Marika M L Laaksonen et al.Bone, 44(5), 1003-1009 (2009-01-27) Genetic predisposition for adult lactose intolerance and relation to diet, bone density, and bone fractures.Barbara M Obermayer-Pietsch et al.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 19(1), 42-47 (2004-02-03) Carbohydrate Malabsorption and Putative Carbohydrate-Specific Small Intestinal Bacterial Overgrowth: Prevalence and Diagnostic Overlap Observed in an Austrian Outpatient Center.Dietmar Enko et al.Digestion, 92(1), 32-38 (2015-07-04) Functional significance of single nucleotide polymorphisms in the lactase gene in diverse US patients and evidence for a novel lactase persistence allele at -13909 in those of European ancestry.Nana Yaa Baffour-Awuah et al.Journal of pediatric gastroenterology and nutrition, 60(2), 182-191 (2015-01-28) 13915*G DNA polymorphism associated with lactase persistence in Africa interacts with Oct-1.Lynne C Olds et al.Human genetics, 129(1), 111-113 (2010-10-21) The -14010*C variant associated with lactase persistence is located between an Oct-1 and HNF1α binding site and increases lactase promoter activity.Tine G K Jensen et al.Human genetics, 130(4), 483-493 (2011-02-18) Adult-type hypolactasia is not a predisposing factor for the early functional and structural changes of atherosclerosis: the Cardiovascular Risk in Young Finns Study.Terho Lehtimäki et al.Clinical science (London, England : 1979), 115(9), 265-271 (2008-01-16) Convergent adaptation of human lactase persistence in Africa and Europe.Sarah A Tishkoff et al.Nature genetics, 39(1), 31-40 (2006-12-13) Associations between lactase persistence and the metabolic syndrome in a cross-sectional study in the Canary Islands.Ricardo Almon et al.European journal of nutrition, 49(3), 141-146 (2009-10-22) Distribution of the -xa013910C>T polymorphism in the general population of Portugal and in subjects with gastrointestinal complaints associated with milk consumption.Licínio Manco et al.Annals of human biology, 40(2), 205-208 (2013-01-19) Hydrogen breath testing versus LCT genotyping for the diagnosis of lactose intolerance: a matter of age?Michaela Kerber et al.Clinica chimica acta; international journal of clinical chemistry, 383(1-2), 91-96 (2007-06-19) Prevalence of lactase persistent/non-persistent genotypes and milk consumption in a young population in north-west Russia.Yulia Khabarova et al.World journal of gastroenterology, 15(15), 1849-1853 (2009-04-17) Evaluation of a new DNA test compared with the lactose hydrogen breath test for the diagnosis of lactase non-persistence.Christoph Högenauer et al.European journal of gastroenterology & hepatology, 17(3), 371-376 (2005-02-18) Identification of a variant associated with adult-type hypolactasia.Nabil Sabri Enattah et al.Nature genetics, 30(2), 233-237 (2002-01-15) Lactose digestion and the evolutionary genetics of lactase persistence.Catherine J E Ingram et al.Human genetics, 124(6), 579-591 (2008-11-27) The T/G 13915 variant upstream of the lactase gene (LCT) is the founder allele of lactase persistence in an urban Saudi population.F Imtiaz et al.Journal of medical genetics, 44(10), e89-e89 (2007-10-04) Lactase persistence/non-persistence genetic variants in irritable bowel syndrome in an endemic area for lactose malabsorption.Sunil Kumar et al.Journal of gastroenterology and hepatology, 27(12), 1825-1830 (2012-09-20) Several different lactase persistence associated alleles and high diversity of the lactase gene in the admixed Brazilian population.Deise C Friedrich et al.PloS one, 7(9), e46520-e46520 (2012-10-03) Genetic test for lactase non-persistence and hydrogen breath test: is genotype better than phenotype to diagnose lactose malabsorption?M Di Stefano et al.Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 41(7), 474-479 (2008-11-18) The -13914G>A variant upstream of the lactase gene (LCT) is associated with lactase persistence/non-persistence.Yulia Khabarova et al.Scandinavian journal of clinical and laboratory investigation, 70(5), 354-357 (2010-06-01) Can lactase persistence genotype be used to reassess the relationship between renal cell carcinoma and milk drinking? Potentials and problems in the application of Mendelian randomization.Nicholas J Timpson et al.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 19(5), 1341-1348 (2010-05-08) Lactose intolerance: a non-allergic disorder often managed by allergologists.A Perino et al.European annals of allergy and clinical immunology, 41(1), 3-16 (2009-06-06) A study on genetic test of lactase persistence in relation to milk consumption in regional groups of India.Shruti V Baadkar et al.Genetic testing and molecular biomarkers, 16(12), 1413-1418 (2012-10-04) In Vitro Functional Analyses of Infrequent Nucleotide Variants in the Lactase Enhancer Reveal Different Molecular Routes to Increased Lactase Promoter Activity and Lactase Persistence.Anke Liebert et al.Annals of human genetics, 80(6), 307-318 (2016-10-08) Theodore E. Woodward Award: lactase persistence SNPs in African populations regulate promoter activity in intestinal cell culture.Eric Sibley et al.Transactions of the American Clinical and Climatological Association, 122, 155-165 (2010-01-01) Genetic variation in the lactase gene, dairy product intake and risk for prostate cancer in the European prospective investigation into cancer and nutrition.Ruth C Travis et al.International journal of cancer, 132(8), 1901-1910 (2012-09-12) Frequency of lactose malabsorption among healthy southern and northern Indian populations by genetic analysis and lactose hydrogen breath and tolerance tests.Janaki Babu et al.The American journal of clinical nutrition, 91(1), 140-146 (2009-11-06) Lactase non-persistence and milk consumption in Estonia.Margus Lember et al.World journal of gastroenterology, 12(45), 7329-7331 (2006-12-05) Genes related to the metabolism of nutrients in the Kola Sami population.Andrew Kozlov et al.International journal of circumpolar health, 67(1), 56-66 (2008-05-13) LCT-13910C>T polymorphism-associated lactose malabsorption and risk for colorectal cancer in Italy.Elena Tarabra et al.Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 42(10), 741-743 (2010-04-07) [Diagnosing lactose intolerance in adults].Mikala Klok Jørgensen et al.Ugeskrift for laeger, 170(42), 3309-3312 (2008-10-23) Association between celiac disease and primary lactase deficiency.M S Basso et al.European journal of clinical nutrition, 66(12), 1364-1365 (2012-12-06) Lactase persistence-related genetic variant: population substructure and health outcomes.George Davey Smith et al.European journal of human genetics : EJHG, 17(3), 357-367 (2008-09-18) Genetic testing for adult-type hypolactasia in Italian families.Monica Mottes et al.Clinical chemistry and laboratory medicine, 46(7), 980-984 (2008-07-09) Herders of Indian and European cattle share their predominant allele for lactase persistence.Irene Gallego Romero et al.Molecular biology and evolution, 29(1), 249-260 (2011-08-13) Polymorphism in the oxytocin promoter region in patients with lactase non-persistence is not related to symptoms.Mikael Truedsson et al.BMC gastroenterology, 9, 90-90 (2009-12-01) Association of the European lactase persistence variant (LCT-13910 C>T polymorphism) with obesity in the Canary Islands.Ricardo Almon et al.PloS one, 7(8), e43978-e43978 (2012-09-01) Effects of the lactase 13910 C/T and calcium-sensor receptor A986S G/T gene polymorphisms on the incidence and recurrence of colorectal cancer in Hungarian population.Krisztián Bácsi et al.BMC cancer, 8, 317-317 (2008-11-05) The LCT 13910 C/T polymorphism as a risk factor for osteoporosis, has no impact on metastatic bone disease in breast cancer.H Clar et al.Breast cancer research and treatment, 112(2), 363-365 (2007-12-18) Correlation between lactose absorption and the C/T-13910 and G/A-22018 mutations of the lactase-phlorizin hydrolase (LCT) gene in adult-type hypolactasia.A C Bulhões et al.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 40(11), 1441-1446 (2007-10-16) Effect of C/T -13910 cis-acting regulatory variant on expression and activity of lactase in Indian children and its implication for early genetic screening of adult-type hypolactasia.Raja A H Kuchay et al.Clinica chimica acta; international journal of clinical chemistry, 412(21-22), 1924-1930 (2011-07-19) Adult-type hypolactasia genotyping in Northern Italy: prevalence of C/T-13910 polymorphism and questions after comparison with existing data.C Ghidini et al.Minerva gastroenterologica e dietologica, 56(1), 19-23 (2010-03-02) Single nucleotide polymorphism C/T(-13910), located upstream of the lactase gene, associated with adult-type hypolactasia: validation for clinical practice.Rejane Mattar et al.Clinical biochemistry, 41(7-8), 628-630 (2008-02-02) The C/C-13910 genotype of adult-type hypolactasia is associated with an increased risk of colorectal cancer in the Finnish population.H Rasinperä et al.Gut, 54(5), 643-647 (2005-04-16) The C/C(-13910) and G/G(-22018) genotypes for adult-type hypolactasia are not associated with inflammatory bowel disease.C Büning et al.Scandinavian journal of gastroenterology, 38(5), 538-542 (2003-06-11) Single-nucleotide polymorphism in Turkish patients with adolescent idiopathic scoliosis: curve progression is not related with MATN-1, LCT C/T-13910, and VDR BsmI.Hurriyet Yilmaz et al.Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 30(9), 1459-1463 (2012-01-27) The genetic variant of lactase persistence C (-13910) T as a risk factor for type I and II diabetes in the Finnish population.N S Enattah et al.European journal of clinical nutrition, 58(9), 1319-1322 (2004-04-01) Distribution of the lactase persistence-associated variant alleles -13910* T and -13915* G among the people of Oman and Yemen.Abdul Rahim Al-Abri et al.Human biology, 84(3), 271-286 (2012-12-22) LCT 13910 C/T polymorphism, serum calcium, and bone mineral density in postmenopausal women.K Bácsi et al.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 20(4), 639-645 (2008-08-16) Genotyping of the lactase-phlorizin hydrolase -13910 polymorphism by LightCycler PCR and implications for the diagnosis of lactose intolerance.Gerd Bodlaj et al.Clinical chemistry, 52(1), 148-151 (2006-01-05) Genetic variant of lactase-persistent C/T-13910 is associated with bone fractures in very old age.Nabil S Enattah et al.Journal of the American Geriatrics Society, 53(1), 79-82 (2005-01-26) Evidence of still-ongoing convergence evolution of the lactase persistence T-13910 alleles in humans.Nabil Sabri Enattah et al.American journal of human genetics, 81(3), 615-625 (2007-08-19) Lactase gene c/t(-13910) polymorphism, calcium intake, and pQCT bone traits in Finnish adults.Sanna Tolonen et al.Calcified tissue international, 88(2), 153-161 (2010-12-08) Decline of lactase activity and c/t-13910 variant in Sardinian childhood.Enrico Schirru et al.Journal of pediatric gastroenterology and nutrition, 45(4), 503-506 (2007-11-22) Measurement of breath hydrogen and methane, together with lactase genotype, defines the current best practice for investigation of lactose sensitivity.Jonathan P Waud et al.Annals of clinical biochemistry, 45(Pt 1), 50-58 (2008-02-16) The effects of adult-type hypolactasia on body height growth and dietary calcium intake from childhood into young adulthood: a 21-year follow-up study--the Cardiovascular Risk in Young Finns Study.Terho Lehtimäki et al.Pediatrics, 118(4), 1553-1559 (2006-10-04) Comparison of lactase persistence polymorphism in ancient and present-day Hungarian populations.Dóra Nagy et al.American journal of physical anthropology, 145(2), 262-269 (2011-03-03) A novel polymorphism associated with lactose tolerance in Africa: multiple causes for lactase persistence?Catherine J E Ingram et al.Human genetics, 120(6), 779-788 (2006-11-23) Prevalence of adult-type hypolactasia as diagnosed with genetic and lactose hydrogen breath tests in Hungarians.D Nagy et al.European journal of clinical nutrition, 63(7), 909-912 (2009-01-22) Lactase persistence DNA variant enhances lactase promoter activity in vitro: functional role as a cis regulatory element.Lynne C Olds et al.Human molecular genetics, 12(18), 2333-2340 (2003-08-14) Genetic lactase non-persistence, consumption of milk products and intakes of milk nutrients in Finns from childhood to young adulthood.Marika M L Laaksonen et al.The British journal of nutrition, 102(1), 8-17 (2009-01-14) Independent introduction of two lactase-persistence alleles into human populations reflects different history of adaptation to milk culture.Nabil Sabri Enattah et al.American journal of human genetics, 82(1), 57-72 (2008-01-09) An upstream polymorphism associated with lactase persistence has increased enhancer activity.Jesper T Troelsen et al.Gastroenterology, 125(6), 1686-1694 (2004-01-16) Body fat and dairy product intake in lactase persistent and non-persistent children and adolescents.Ricardo Almon et al.Food & nutrition research, 54 (2010-06-30) Genetic testing improves the diagnosis of adult type hypolactasia in the Mediterranean population of Sardinia.E Schirru et al.European journal of clinical nutrition, 61(10), 1220-1225 (2007-02-22) A genetic test which can be used to diagnose adult-type hypolactasia in children.H Rasinperä et al.Gut, 53(11), 1571-1576 (2004-10-14) Molecularly defined lactose malabsorption, peak bone mass and bone turnover rate in young finnish men.N Enattah et al.Calcified tissue international, 75(6), 488-493 (2004-09-15) Transcriptional regulation of the lactase-phlorizin hydrolase gene by polymorphisms associated with adult-type hypolactasia.M Kuokkanen et al.Gut, 52(5), 647-652 (2003-04-15) Molecularly defined adult-type hypolactasia among working age people with reference to milk consumption and gastrointestinal symptoms.Sari R Anthoni et al.World journal of gastroenterology, 13(8), 1230-1235 (2007-04-25) Genotyping of the lactase-phlorizin hydrolase c/t-13910 polymorphism by means of a new rapid denaturing high-performance liquid chromatography-based assay in healthy subjects and colorectal cancer patients.Ada Piepoli et al.Journal of biomolecular screening, 12(5), 733-739 (2007-05-05) T-13910 DNA variant associated with lactase persistence interacts with Oct-1 and stimulates lactase promoter activity in vitro.Rikke H Lewinsky et al.Human molecular genetics, 14(24), 3945-3953 (2005-11-23) Mitochondrial DNA genetic diversity and LCT-13910 and deltaF508 CFTR alleles typing in the medieval sample from Poland.T Płoszaj et al.Homo : internationale Zeitschrift fur die vergleichende Forschung am Menschen, 66(3), 229-250 (2015-04-22)

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