Melting point	23 ºC
Water Solubility	3.6 g/100 mL (20 ºC)
Boiling point	161 ºC
Flash point	67 ºC
Density	0.948
Refractive index	1.463-1.467

Symbol(GHS)	Xn
Hazard Codes	R20/22;R37/38
SDS/MSDS	S24/25

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Antidepressant-like effects of paeoniflorin on the behavioural, biochemical, and neurochemical patterns of rats exposed to chronic unpredictable stress.Feng-Mei Qiu et al.Neuroscience letters, 541, 209-213 (2013-03-14) Anticonvulsive effect of paeoniflorin on experimental febrile seizures in immature rats: possible application for febrile seizures in children.Hitomi Hino et al.PloS one, 7(8), e42920-e42920 (2012-08-24) Paeoniflorin protects against ischemia-induced brain damages in rats via inhibiting MAPKs/NF-κB-mediated inflammatory responses.Ruo-Bing Guo et al.PloS one, 7(11), e49701-e49701 (2012-11-21) Detection of paeoniflorin and albiflorin by immunostaining technique using anti-paeoniflorin monoclonal antibody.Osamu Morinaga et al.Phytochemical analysis : PCA, 24(2), 124-128 (2012-07-12) Pharmacokinetic study of multiple active constituents after oral gavage of Guizhi decoction in rats using a LC-MS/MS method.Yingrong Chen et al.European journal of drug metabolism and pharmacokinetics, 38(4), 283-293 (2013-02-23) [Comparative study on effects of blood enriching on mouse model of blood deficiency syndrome induced by compound method of bleeding, starved feeding and exhausting of Paeoniae Radix Alba and Paeoniae Radix Rubra, paeoniflorin and albiflorin].Jian-Jun Zhang et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(19), 3358-3362 (2014-01-16) Paeoniflorin inhibits function and down-regulates HLA-DR and CD80 expression of human peripheral blood monocytes stimulated by rhIL-1β.Di Wang et al.International immunopharmacology, 14(2), 172-178 (2012-07-28) [Treatment of premenstrual syndrome with Chinese medicine formula, baixiangdan capsule: implications for neuron viability and GABA(A) receptor modulation in rat cortex].Shiguang Sun et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(11), 1508-1511 (2012-07-12) [Screening and identifying of hepatoprotective compounds in paeoniae radix rubra].Lin Lu et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(5), 597-600 (2012-06-15) Paeoniflorin in experimental BALB/c mansoniasis: A novel anti-angiogenic therapy.Naglaa Fathy Abd El-Aal et al.Experimental parasitology, 197, 85-92 (2018-11-12) Evaluation of a water extract of So-Cheong-Ryong-Tang for acute toxicity and genotoxicity using in vitro and in vivo tests.Mee-Young Lee et al.BMC complementary and alternative medicine, 15, 235-235 (2015-07-17) [Multi-channel analysis and comparison on absorption difference between paeoniflorin and Paeonia lactiflora extracts].Yan Chen et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(13), 2012-2016 (2012-10-02) Paeoniflorin protects human EA.hy926 endothelial cells against gamma-radiation induced oxidative injury by activating the NF-E2-related factor 2/heme oxygenase-1 pathway.Jing Yu et al.Toxicology letters, 218(3), 224-234 (2013-02-14) [Advance in studies on effect of paeoniflorin on nervous system].Zeng-Yao Hu et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(3), 297-301 (2013-05-15) Paeoniflorin protects myocardial cell from doxorubicin-induced apoptosis through inhibition of NADPH oxidase.Jian-Zhe Li et al.Canadian journal of physiology and pharmacology, 90(12), 1569-1575 (2012-12-06) Pharmacokinetics of paeoniflorin microemulsion after repeated dosing in rats with adjuvant arthritis.Chun Wang et al.Die Pharmazie, 67(12), 997-1001 (2013-01-26) Paeoniflorin relieves LPS-induced inflammatory pain in mice by inhibiting NLRP3 inflammasome activation via transient receptor potential vanilloid 1.Nina Yin et al.Journal of leukocyte biology, 108(1), 229-241 (2020-02-23) Paeoniflorin regulates macrophage activation in dimethylnitrosamine-induced liver fibrosis in rats.Xiaorong Chen et al.BMC complementary and alternative medicine, 12, 254-254 (2012-12-15) [Advanced achievements about neuroprotective mechanisms of paeoniflorin].Yefang Zhu et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 35(11), 1490-1493 (2010-09-09) Paeoniflorin attenuates lipopolysaccharide-induced permeability of endothelial cells: involvements of F-actin expression and phosphorylations of PI3K/Akt and PKC.Huan Xu et al.Inflammation, 36(1), 216-225 (2012-10-12) Chemical profiling and quantification of Gua-Lou-Gui-Zhi decoction by high performance liquid chromatography/quadrupole-time-of-flight mass spectrometry and ultra-performance liquid chromatography/triple quadrupole mass spectrometry.Wen Xu et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 986-987, 69-84 (2015-02-25) Effects of Chaihu-Shugan-San on Small Intestinal Interstitial Cells of Cajal in Mice.Minwoo Hwang et al.Biological & pharmaceutical bulletin, 43(4), 707-715 (2020-04-03) Simultaneous determination of 11 major components in Palmul-tang by HPLC-DAD and LC-MS-MS.Bohyoung Lee et al.Journal of chromatographic science, 52(6), 482-492 (2013-06-07) Mechanisms involved in the therapeutic effects of Paeonia lactiflora Pallas in rheumatoid arthritis.Wei Zhang et al.International immunopharmacology, 14(1), 27-31 (2012-06-19) [Protective effect of paeoniflorin on Abeta25-35 -induced PC12 cell injury].Shuying Wang et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(16), 2448-2451 (2012-12-14) Jin Gui Shen Qi Wan, a traditional Chinese medicine, alleviated allergic airway hypersensitivity and inflammatory cell infiltration in a chronic asthma mouse model.Shung-Te Kao et al.Journal of ethnopharmacology, 227, 181-190 (2018-09-02) Two-step inhibitory effect of kanzo on oxytocin-induced and prostaglandin F2α-induced uterine myometrial contractions.Genichiro Sumi et al.Journal of natural medicines, 68(3), 550-560 (2014-04-18) [Influence of different solutions on extracting of active components in Danggui Chishao drug pair].Wen Ding et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(7), 916-919 (2012-07-17) [Impact of saikosaponin on absorption and transport of paeoniflorin in Caco-2 cell model].Yan Chen et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(12), 1850-1854 (2012-09-25) Pro-apoptotic effect of epigallo-catechin-3-gallate on B lymphocytes through regulating BAFF/PI3K/Akt/mTOR signaling in rats with collagen-induced arthritis.Dandan Liu et al.European journal of pharmacology, 690(1-3), 214-225 (2012-07-05) Sedative and hypnotic effect of freeze-dried paeoniflorin and sini san freeze-dried powder in pentobarbital sodium-induced mice.Yuefeng Li et al.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 34(2), 184-187 (2014-05-03) Detection of sulfur-fumigated Paeoniae Alba Radix in complex preparations by high performance liquid chromatography tandem mass spectrometry.Jie Wu et al.Molecules (Basel, Switzerland), 17(8), 8938-8954 (2012-07-28) [Pharmacokinetic study on three main ingredients of refined coronary cataplasm].Rui Hou et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(23), 3641-3646 (2013-03-13) Paeoniflorin acts as a liver X receptor agonist.Hsiang-Ru Lin Journal of Asian natural products research, 15(1), 35-45 (2013-01-04) Paeoniflorin attenuates early brain injury through reducing oxidative stress and neuronal apoptosis after subarachnoid hemorrhage in rats.Tao Wang et al.Metabolic brain disease, 35(6), 959-970 (2020-04-05) Preparative purification of peoniflorin and albiflorin from peony rhizome using macroporous resin and medium-pressure liquid chromatography.Rong Wang et al.Journal of separation science, 35(15), 1985-1992 (2012-06-08) Involvement of the prostaglandin E receptor EP2 in paeoniflorin-induced human hepatoma cell apoptosis.Shanshan Hu et al.Anti-cancer drugs, 24(2), 140-149 (2012-10-17) [Primary safety evaluation of sulfated paeoniae radix alba].Shan-Jun Huang et al.Yao xue xue bao = Acta pharmaceutica Sinica, 47(4), 486-491 (2012-07-17) Food- and gender-dependent pharmacokinetics of paeoniflorin after oral administration with Samul-tang in rats.Youn-Hwan Hwang et al.Journal of ethnopharmacology, 142(1), 161-167 (2012-05-01)

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