Melting point	-92 ºC
Boiling point	164-165 ºC
Flash point	49 ºC
Density	0.8675
Refractive index	1.405-1.407

Hazard Codes	R10
SDS/MSDS	S2

Source	SDS/MSDS Samples
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Articles

Peer-Reviewed Papers

Adenine nucleotide control of coronary blood flow during exercise.Mark W Gorman et al.American journal of physiology. Heart and circulatory physiology, 299(6), H1981-H1989 (2010-09-21) Control of hypertension in rats using volatile components of leaves of Taxus chinensis var. mairei.Wei-Xia Yang et al.Journal of ethnopharmacology, 141(1), 309-313 (2012-03-10) Relaxant effect of flavonoid naringenin on contractile activity of rat colonic smooth muscle.ZiHuan Yang et al.Journal of ethnopharmacology, 155(2), 1177-1183 (2014-07-06) Tempol improves cutaneous thermal hyperemia through increasing nitric oxide bioavailability in young smokers.Naoto Fujii et al.American journal of physiology. Heart and circulatory physiology, 306(11), H1507-H1511 (2014-04-01) Muscarinic receptor subtypes involved in urothelium-derived relaxatory effects in the inflamed rat urinary bladder.M Andersson et al.Autonomic neuroscience : basic & clinical, 170(1-2), 5-11 (2012-07-14) The effects of 5-hydroxytryptamine1a receptor agonist, buspirone on the gastric fundus accommodation in an animal model using guinea pigs.Y H Youn et al.Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 27(4), 532-541 (2015-02-14) Controlled ingestion of kaolinite (5%) modulates enteric nitrergic innervation in rats.Florian Voinot et al.Fundamental & clinical pharmacology, 28(4), 405-413 (2013-06-27) Nebivolol-induced vasodilation of renal afferent arterioles involves β3-adrenergic receptor and nitric oxide synthase activation.Ming-Guo Feng et al.American journal of physiology. Renal physiology, 303(5), F775-F782 (2012-06-08) Pannexin 1 facilitates arterial relaxation via an endothelium-derived hyperpolarization mechanism.Dina Gaynullina et al.FEBS letters, 589(10), 1164-1170 (2015-03-31) Inducible NOS mediates CNP-induced relaxation of intestinal myofibroblasts.Yishi Chen et al.American journal of physiology. Gastrointestinal and liver physiology, 304(7), G673-G679 (2013-01-26) Reversible inhibition of vasoconstriction by thiazolidinediones related to PI3K/Akt inhibition in vascular smooth muscle cells.Tiziana Sinagra et al.Biochemical pharmacology, 85(4), 551-559 (2012-12-01) Comp Biochem Physiol A Mol Integr PhysiolSchwerte T, et al. The Journal of Experimental Biology, 202(8), 1005-1013 (1999) Changes in nitrergic and tachykininergic pathways in rat proximal colon in response to chronic treatment with otilonium bromide.G Cipriani et al.Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 27(7), 997-1009 (2015-05-02) NOS inhibition enhances myogenic tone by increasing rho-kinase mediated Ca2+ sensitivity in the male but not the female gerbil spiral modiolar artery.Katrin Reimann et al.PloS one, 8(1), e53655-e53655 (2013-01-10) Nitric oxide modulated the expression of DREAM/calsenilin/KChIP3 in inflammatory pain of rats.Hong-Bo Jin et al.Inflammation, 35(6), 1867-1871 (2012-07-21) Chronic rapamycin restores brain vascular integrity and function through NO synthase activation and improves memory in symptomatic mice modeling Alzheimer's disease.Ai-Ling Lin et al.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 33(9), 1412-1421 (2013-06-27) Fluid resuscitation therapy in endotoxemic hamsters improves survival and attenuates capillary perfusion deficits and inflammatory responses by a mechanism related to nitric oxide.Nivaldo Ribeiro Villela et al.Journal of translational medicine, 12, 232-232 (2014-08-26) L-NOARG-induced catalepsy can be influenced by glutamatergic neurotransmission mediated by NMDA receptors in the inferior colliculus.A P Iacopucci et al.Behavioural brain research, 234(2), 149-154 (2012-07-04) Neurogenic contractions in intraocular porcine ciliary arteries are mediated by α₂-adrenoceptors and NPY₁ receptors and are inhibited by prostaglandin E₂ acting on prejunctional EP₄ receptors.Sidse Kringelholt et al.Experimental eye research, 107, 32-36 (2012-11-28) Evidence that nitric oxide is a non-adrenergic non-cholinergic inhibitory neurotransmitter in the circular muscle of the mouse distal colon: a study on the mechanism of nitric oxide-induced relaxation.Kazuhiro Nishiyama et al.Pharmacology, 94(3-4), 99-108 (2014-09-18) [Effect of immobilization-painful stress on cardiac ino- and chronotropic functions of animals under the conditions of nitric oxide synthesis supression].I N Tiurenkov et al.Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 98(9), 1131-1139 (2013-01-09) Cutaneous vascular and sweating responses to intradermal administration of ATP: a role for nitric oxide synthase and cyclooxygenase?Naoto Fujii et al.The Journal of physiology, 593(11), 2515-2525 (2015-03-27) Loss of SOD3 (EcSOD) Expression Promotes an Aggressive Phenotype in Human Pancreatic Ductal Adenocarcinoma.Brianne R O'Leary et al.Clinical cancer research : an official journal of the American Association for Cancer Research, 21(7), 1741-1751 (2015-01-31) Toll-Like Receptor 4 Promotes NO Synthesis by Upregulating GCHI Expression under Oxidative Stress Conditions in Sheep Monocytes/Macrophages.Shoulong Deng et al.Oxidative medicine and cellular longevity, 2015, 359315-359315 (2015-11-18) Characteristics of emodin on modulating the contractility of jejunal smooth muscle.Dapeng Chen et al.Canadian journal of physiology and pharmacology, 90(4), 455-462 (2012-03-29) Nitric oxide modulates excitation-contraction coupling in the diaphragmReid M B, et al. Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology, 119(1), 211-218 (1998) Resveratrol Ameliorates Clonidine-Induced Endothelium-Dependent Relaxation Involving Akt and Endothelial Nitric Oxide Synthase Regulation in Type 2 Diabetic Mice.Kumiko Taguchi et al.Biological & pharmaceutical bulletin, 38(12), 1864-1872 (2015-12-04) Involvement of nitric oxide in oxidative burst, phenylalanine ammonia-lyase activation and Taxol production induced by low-energy ultrasound in Taxus yunnanensis cell suspension cultures.Wang JW Nitric Oxide, 15(4), 351-358 (2006) L-NNA decreases cortical hyperemia and brain cGMP levels following CO2 inhalation in Sprague-Dawley ratsIrikura K, et al. The American Journal of Physiology, 267(2), H837-H843 (1994) Cerebrovascular dysfunction and blood-brain barrier permeability induced by oxidized LDL are prevented by apocynin and magnesium sulfate in female rats.Malou P H Schreurs et al.Journal of cardiovascular pharmacology, 63(1), 33-39 (2013-10-03) Modulation of mitochondrial capacity and angiogenesis by red wine polyphenols via estrogen receptor, NADPH oxidase and nitric oxide synthase pathways.Lucie Duluc et al.The international journal of biochemistry & cell biology, 45(4), 783-791 (2013-01-22) Relative contribution of SKCa and TREK1 channels in purinergic and nitrergic neuromuscular transmission in the rat colon.V Gil et al.American journal of physiology. Gastrointestinal and liver physiology, 303(3), G412-G423 (2012-05-29) Effect of Nitric Oxide Synthesis Blockade on the Morphology of Langerhans Islets in August and Wistar Rats with Acute Alloxan Diabetes.E A Smirnova et al.Bulletin of experimental biology and medicine, 159(2), 273-277 (2015-06-19) A Study of the Relaxed Mechanisms Induced by Novokinin in the Isolated Porcine Coronary Artery Ring Segments.PeiHan Xu et al.Protein and peptide letters, 22(12), 1083-1088 (2015-09-24) Cyclic GMP is a second messenger by which nitric oxide inhibits diaphragm contractionAbraham R Z, et al. Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology, 119(1), 177-183 (1998) Characterization of 5-hydroxytryptamine-induced contraction and acetylcholine-induced relaxation in isolated chicken basilar artery.F Matsumoto et al.Poultry science, 91(5), 1158-1164 (2012-04-14) Functional role of vasoactive intestinal polypeptide in inhibitory motor innervation in the mouse internal anal sphincter.K D Keef et al.The Journal of physiology, 591(6), 1489-1506 (2013-01-23) Nitric oxide has no obligatory role in isoflurane late preconditioning against myocardial stunning.Song-Jung Kim et al.Life sciences, 91(23-24), 1201-1206 (2012-10-10) Prion protein and copper cooperatively protect neurons by modulating NMDA receptor through S-nitrosylation.Lisa Gasperini et al.Antioxidants & redox signaling, 22(9), 772-784 (2014-12-10) Effects of dimethylarginine dimethylaminohydrolase-1 overexpression on the response of the pulmonary vasculature to hypoxia.Adel Bakr et al.American journal of respiratory cell and molecular biology, 49(3), 491-500 (2013-05-07) Relaxation Induced by Atrial Natriuretic Peptide Is Impaired in Carotid but Not Renal Arteries from Spontaneously Hypertensive Rats Due to Reduced BKCa Channel Activity.Takayuki Matsumoto et al.Biological & pharmaceutical bulletin, 38(11), 1801-1808 (2015-11-03) Human blood platelets lack nitric oxide synthase activity.Anke Böhmer et al.Platelets, 26(6), 583-588 (2014-11-02) Network analysis of immunotherapy-induced regressing tumours identifies novel synergistic drug combinations.W Joost Lesterhuis et al.Scientific reports, 5, 12298-12298 (2015-07-22) Region-related modular nerve-dependent motor activity in anorectum--cholinergic and nitrergic contribution to rat model.Galya Stavreva et al.Acta neurobiologiae experimentalis, 72(2), 185-193 (2012-07-20) Carnosine prevents necrotic and apoptotic death of rat thymocytes via ouabain-sensitive Na/K-ATPase.Larisa V Smolyaninova et al.Cell biochemistry and function, 31(1), 30-35 (2012-07-06) Bimodal effect of oxidative stress in internal anal sphincter smooth muscle.Jagmohan Singh et al.American journal of physiology. Gastrointestinal and liver physiology, 309(5), G292-G300 (2015-07-04) Brain endothelial TAK1 and NEMO safeguard the neurovascular unit.Dirk A Ridder et al.The Journal of experimental medicine, 212(10), 1529-1549 (2015-09-09) Prevention of the degeneration of human dopaminergic neurons in an astrocyte co-culture system allowing endogenous drug metabolism.Liudmila Efremova et al.British journal of pharmacology, 172(16), 4119-4132 (2015-05-20) Endogenous oestrogens do not regulate endothelial nitric oxide production in early postnatal rats.Svetlana I Sofronova et al.European journal of pharmacology, 765, 598-605 (2015-09-30) Is there a nitrergic modulation of the rat external anal sphincter?J Evers et al.Experimental physiology, 98(2), 397-404 (2012-08-09) Role of Telokin in Regulating Murine Gastric Fundus Smooth Muscle Tension.Changlong An et al.PloS one, 10(8), e0134876-e0134876 (2015-08-11) A high frequency of MDSCs in sepsis patients, with the granulocytic subtype dominating in gram-positive cases.Helena Janols et al.Journal of leukocyte biology, 96(5), 685-693 (2014-06-15) Involvement of neurotransmitters in the action of apelin-13 on passive avoidance learning in mice.Gyula Telegdy et al.Peptides, 39, 171-174 (2012-11-08) Ubiquitination of neuronal nitric-oxide synthase in the calmodulin-binding site triggers proteasomal degradation of the protein.Kelly M Clapp et al.The Journal of biological chemistry, 287(51), 42601-42610 (2012-10-31) Evidence for the gastric cytoprotective effect of centrally injected agmatine.Zoltán S Zádori et al.Brain research bulletin, 108, 51-59 (2014-08-31) Intraplantar injection of tetrahydrobiopterin induces nociception in mice.Arafat Nasser et al.Neuroscience letters, 584, 247-252 (2014-12-03) A newly synthesized compound, 4'-geranyloxyferulic acid-N(omega)-nitro-L-arginine methyl ester suppresses inflammation-associated colorectal carcinogenesis in male mice.Masahito Shimizu et al.International journal of cancer, 135(4), 774-784 (2014-01-30) The threshold of pentylenetetrazole-induced convulsive seizures, but not that of nonconvulsive seizures, is controlled by the nitric oxide levels in murine brains.Masatomo Watanabe et al.Experimental neurology, 247, 645-652 (2013-03-19) Origin of endogenous nitric oxide released in the nucleus accumbens under real-time in vivo conditions.Helmut Prast et al.Life sciences, 134, 79-84 (2015-05-27) Inhibition of endothelial nitric oxyde synthase increases capillary formation via Rac1-dependent induction of hypoxia-inducible factor-1α and plasminogen activator inhibitor-1.Andreas Petry et al.Thrombosis and haemostasis, 108(5), 849-862 (2012-09-28) S-Nitrosylating protein disulphide isomerase mediates α-synuclein aggregation caused by methamphetamine exposure in PC12 cells.Xiao-Fang Wu et al.Toxicology letters, 230(1), 19-27 (2014-08-05) The threshold of pentylenetetrazole-induced convulsive seizures, but not that of nonconvulsive seizures, is controlled by the nitric oxide levels in murine brains.Masatomo Watanabe et al.Experimental neurology, 247, 645-652 (2013-03-19) NMDA Receptor Plasticity in the Hypothalamic Paraventricular Nucleus Contributes to the Elevated Blood Pressure Produced by Angiotensin II.Michael J Glass et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(26), 9558-9567 (2015-07-03) Reduced NO production rapidly aggravates renal function through the NF-κB/ET-1/ETA receptor pathway in DOCA-salt-induced hypertensive rats.Kimihiro Kimura et al.Life sciences, 91(13-14), 644-650 (2012-05-10) Knockdown of angiopoietin like-2 protects against angiotensin II-induced cerebral endothelial dysfunction in mice.Carol Yu et al.American journal of physiology. Heart and circulatory physiology, 308(5), H386-H397 (2014-12-21) Astroglial NMDA receptors inhibit expression of Kir4.1 channels in glutamate-overexposed astrocytes in vitro and in the brain of rats with acute liver failure.Marta Obara-Michlewska et al.Neurochemistry international, 88, 20-25 (2014-12-03) Reduced vascular responses to soluble guanylyl cyclase but increased sensitivity to sildenafil in female rats with type 2 diabetes.Styliani Goulopoulou et al.American journal of physiology. Heart and circulatory physiology, 309(2), H297-H304 (2015-05-10) Nitric oxide-producing myeloid-derived suppressor cells inhibit vascular E-selectin expression in human squamous cell carcinomas.Ahmed E Gehad et al.The Journal of investigative dermatology, 132(11), 2642-2651 (2012-06-22) NO-donating oximes relax corpora cavernosa through mechanisms other than those involved in arterial relaxation.Bart Pauwels et al.The journal of sexual medicine, 11(7), 1664-1674 (2014-05-21) KCa 3.1 channels maintain endothelium-dependent vasodilatation in isolated perfused kidneys of spontaneously hypertensive rats after chronic inhibition of NOS.Serge Simonet et al.British journal of pharmacology, 167(4), 854-867 (2012-06-01)

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