Melting point	-130 ºC
Water Solubility	Insoluble
Boiling point	36 ºC
Flash point	-49 ºC
Density	0.626
Refractive index	1.358

Symbol(GHS)	F+;Xn;N
Hazard Codes	R12;R51/53;R65;R66;R67
SDS/MSDS	S16;S29;S33;S61;S62;S9

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Exposure of hairdressers to ortho- and meta-toluidine in hair dyes.Gabriella M Johansson et al.Occupational and environmental medicine, 72(1), 57-63 (2014-06-11) [Separation performance of 1-microm silica particles as stationary phase for pressurized electrochromatography].Qishu Qu et al.Se pu = Chinese journal of chromatography, 28(3), 260-263 (2010-06-17) Inflammation rapidly modulates the expression of ALDH1A1 (RALDH1) and vimentin in the liver and hepatic macrophages of rats in vivo.Kyoko Ito et al.Nutrition & metabolism, 11, 54-54 (2014-01-01) Molecular self assembly of mixed comb-like dextran surfactant polymers for SPR virus detection.Katanchalee Mai-Ngam et al.Carbohydrate polymers, 112, 440-447 (2014-08-19) Degradation of o-toluidine by fluidized-bed Fenton process: statistical and kinetic study.Jin Anotai et al.Environmental science and pollution research international, 19(1), 169-176 (2011-06-28) o‑Toluidine and its hydrochloride. Report on carcinogens : carcinogen profiles, 12, 416-418 (2011-08-25) Structure and internal rotation in the S(0) and S(1) states of o-toluidine studied by high resolution UV spectroscopy.Ivo Kalkman et al.Physical chemistry chemical physics : PCCP, 11(21), 4311-4318 (2009-05-22) Methane digester effluent from swine excreta as a nutrient and water source for growing and finishing swine.T L Veum et al.Journal of animal science, 93(1), 197-208 (2015-01-09) Determination of 2,5-toluylenediamine (2,5-TDA) and aromatic amines in urine after personal application of hair dyes: kinetics and doses.Thomas Schettgen et al.Archives of toxicology, 85(2), 127-133 (2010-06-16) Sensitive ionization of non-volatile analytes using protein solutions as spray liquid in desorption electrospray ionization mass spectrometry.Zhiqiang Zhu et al.Rapid communications in mass spectrometry : RCM, 26(23), 2770-2776 (2012-11-06) Monoarylamines in the general population--a cross-sectional population-based study including 1004 Bavarian subjects.Birgitta Kütting et al.International journal of hygiene and environmental health, 212(3), 298-309 (2008-09-16) Comparison of o-toluidine degradation by Fenton, electro-Fenton and photoelectro-Fenton processes.Jin Anotai et al.Journal of hazardous materials, 196, 395-401 (2011-10-19) Electrochemical degradation of waters containing O-toluidine on PbO2 and BDD anodes.Emna Hmani et al.Journal of hazardous materials, 170(2-3), 928-933 (2009-06-23) Methods of high integrity RNA extraction from cell/agarose construct.Takahiro Ogura et al.BMC research notes, 8, 644-644 (2015-11-06) DNA adducts of ortho-toluidine in human bladder.Francine Böhm et al.Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 16(2), 120-128 (2010-12-02) The promotional effect of water-soluble extractives on the enzymatic cellulose hydrolysis of pretreated wheat straw.A T Smit et al.Bioresource technology, 243, 994-999 (2017-07-30) IFITM1 promotes the metastasis of human colorectal cancer via CAV-1.Fang Yu et al.Cancer letters, 368(1), 135-143 (2015-08-12) Ultrastructural characterization of mesenchymal stromal cells labeled with ultrasmall superparamagnetic iron-oxide nanoparticles for clinical tracking studies.Louise Hansen et al.Scandinavian journal of clinical and laboratory investigation, 74(5), 437-446 (2014-04-17) Exposure to o-toluidine, aniline, and nitrobenzene in a rubber chemical manufacturing plant: a retrospective exposure assessment update.Kevin W Hanley et al.Journal of occupational and environmental hygiene, 9(8), 478-490 (2012-06-20) Transcriptional dynamics of a conserved gene expression network associated with craniofacial divergence in Arctic charr.Ehsan Pashay Ahi et al.EvoDevo, 5(1), 40-40 (2014-11-25) Establishing a total allowable concentration of o-toluidine in drinking water incorporating early lifestage exposure and susceptibility.J Caroline English et al.Regulatory toxicology and pharmacology : RTP, 64(2), 269-284 (2012-09-04) Bladder cancer risks in workers manufacturing chemicals for the rubber industry.Tom Sorahan Occupational medicine (Oxford, England), 58(7), 496-501 (2008-08-30) Percutaneous absorption of aromatic amines - a contribution for human health risk assessment.T Wellner et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 46(6), 1960-1968 (2008-03-18) Peripheral nerve injury induces persistent vascular dysfunction and endoneurial hypoxia, contributing to the genesis of neuropathic pain.Tony K Y Lim et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(8), 3346-3359 (2015-02-27) TRPV4 regulates the integrity of the blood-cerebrospinal fluid barrier and modulates transepithelial protein transport.Keishi Narita et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(6), 2247-2259 (2015-02-15) Anaerobic metabolism of 1-amino-2-naphthol-based azo dyes (Sudan dyes) by human intestinal microflora.Haiyan Xu et al.Applied and environmental microbiology, 73(23), 7759-7762 (2007-10-16) Liver nuclear and microsomal CYP2E1-mediated metabolism of xenobiotics in rats chronically drinking an alcohol-containing liquid diet.Maria I Diaz Gómez et al.Toxicology and industrial health, 22(9), 367-374 (2007-05-31) Kinetics of mast cell migration during transplantation tolerance.Gregor Bond et al.Transplant immunology, 32(1), 40-45 (2014-12-03) Oxidative copolymers of aniline with o-toluidine: Their structure and thermal properties.Huang M-R, et al. Journal of Applied Polymer Science, 81(8), 1838-1847 (2001) An o-toluidine method for body-fluid glucose determination.Kurt M Dubowski Clinical chemistry, 54(11), 1919-1920 (2008-10-30) Electrochemical copolymerization study of o-toluidine and o-aminophenol by the simultaneous EQCM and in situ FTIR spectroelectrochemistry.Qin Yang et al.Talanta, 81(1-2), 664-672 (2010-03-02) Deficiency in monocarboxylate transporter 1 (MCT1) in mice delays regeneration of peripheral nerves following sciatic nerve crush.Brett M Morrison et al.Experimental neurology, 263, 325-338 (2014-12-03) Assessment of the medicines lidocaine, prilocaine, and their metabolites, 2,6-dimethylaniline and 2-methylaniline, for DNA adduct formation in rat tissues.Jian-Dong Duan et al.Drug metabolism and disposition: the biological fate of chemicals, 36(8), 1470-1475 (2008-05-21) Self-assembly directed synthesis of poly(ortho-toluidine)-metal(gold and palladium) composite nanospheres.Kakarla Raghava Reddy et al.Journal of nanoscience and nanotechnology, 7(9), 3117-3125 (2007-11-21) Increased bladder cancer risk among workers exposed to o-toluidine and aniline: a reanalysis.Tania Carreón et al.Occupational and environmental medicine, 67(5), 348-350 (2009-11-04) Toxicity identification and reduction of wastewaters from a pigment manufacturing factory.Hun-Je Jo et al.Chemosphere, 70(6), 949-957 (2007-09-26) Enhancement of percutaneous penetration of aniline and o-toluidine in vitro using skin barrier creams.Gintautas Korinth et al.Toxicology in vitro : an international journal published in association with BIBRA, 22(3), 812-818 (2007-12-25) Comparison of exposure to selected cigarette smoke constituents in adult smokers and nonsmokers in a European, multicenter, observational study.Dirk Lindner et al.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 20(7), 1524-1536 (2011-05-27) Relationship between Expression of Cellular Receptor-27.8 kDa and Lymphocystis Disease Virus (LCDV) Infection.Ronghua Wu et al.PloS one, 10(5), e0127940-e0127940 (2015-05-30) Ferrocene-based guanidine derivatives: in vitro antimicrobial, DNA binding and docking supported urease inhibition studies.Rukhsana Gul et al.European journal of medicinal chemistry, 85, 438-449 (2014-08-12) Mouse strain resistant to N-, B-, and NB-tropic murine leukemia viruses.K Kai et al.Journal of virology, 20(2), 436-440 (1976-11-01) Tissue Localization of Lymphocystis Disease Virus (LCDV) Receptor-27.8 kDa and Its Expression Kinetics Induced by the Viral Infection in Turbot (Scophthalmus maximus).Xiuzhen Sheng et al.International journal of molecular sciences, 16(11), 26506-26519 (2015-11-12) Ligamentization of Autogenous Hamstring Grafts After Anterior Cruciate Ligament Reconstruction: Midterm Versus Long-term Results.Shikui Dong et al.The American journal of sports medicine, 43(8), 1908-1917 (2015-06-03) In situ synthesis of copper nanoparticles and poly (< i> o</i>-toluidine): A metal-polymer composite material.Mallick K, et al. Eur. Polymer J., 42(3), 670-675 (2006) Toxicological assessment of kretek cigarettes: Part 1: background, assessment approach, and summary of findings.E Roemer et al.Regulatory toxicology and pharmacology : RTP, 70 Suppl 1, S2-14 (2014-12-17) Rax Homeoprotein Regulates Photoreceptor Cell Maturation and Survival in Association with Crx in the Postnatal Mouse Retina.Shoichi Irie et al.Molecular and cellular biology, 35(15), 2583-2596 (2015-05-20) Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).Giulia Caron et al.Journal of medicinal chemistry, 48(9), 3269-3279 (2005-04-29) A Novel Method for Assessing Drug Degradation Product Safety Using Physiologically-Based Pharmacokinetic Models and Stochastic Risk Assessment.Hoa Q Nguyen et al.Journal of pharmaceutical sciences, 104(9), 3101-3119 (2015-04-23) An investigation on electronic nose diagnosis of lung cancer.Arnaldo D'Amico et al.Lung cancer (Amsterdam, Netherlands), 68(2), 170-176 (2009-12-05) In vitro and in vivo evaluation of a hydrogel reservoir as a continuous drug delivery system for inner ear treatment.Mareike Hütten et al.PloS one, 9(8), e104564-e104564 (2014-08-12) Emergence of an Ancestral Glycoprotein Hormone in the Pituitary of the Sea Lamprey, a Basal Vertebrate.Stacia A Sower et al.Endocrinology, 156(8), 3026-3037 (2015-06-13) Optimizations of packed sorbent and inlet temperature for large volume-direct aqueous injection-gas chromatography to determine high boiling volatile organic compounds in water.Bofan Yu et al.Journal of chromatography. A, 1356, 221-229 (2014-07-07) Septal Glucagon-Like Peptide 1 Receptor Expression Determines Suppression of Cocaine-Induced Behavior.Anne E Harasta et al.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(8), 1969-1978 (2015-02-12)

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