Melting point	-38 ºC
Water Solubility	0.24 g/100 mL (20 ºC)
Boiling point	161-163 ºC
Flash point	40 ºC
Density	1.16
Refractive index	1.453-1.455

Symbol(GHS)	Xi
Hazard Codes	R10;R36/37/38
SDS/MSDS	S26;S36

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Most human proteins made in both nucleus and cytoplasm turn over within minutes.Sabyasachi Baboo et al.PloS one, 9(6), e99346-e99346 (2014-06-10) Extrasynaptic glutamate release through cystine/glutamate antiporter contributes to ischemic damage.Federico N Soria et al.The Journal of clinical investigation, 124(8), 3645-3655 (2014-07-19) Augmented cystine-glutamate exchange by pituitary adenylate cyclase-activating polypeptide signaling via the VPAC1 receptor.Jon M Resch et al.Synapse (New York, N.Y.), 0 (2014-07-30) Inactivation of human salivary glutathione transferase P1-1 by hypothiocyanite: a post-translational control system in search of a role.Raffaele Fabrini et al.PloS one, 9(11), e112797-e112797 (2014-11-14) Comparison of FecalSwab and ESwab devices for storage and transportation of Diarrheagenic bacteria.Jari J Hirvonen et al.Journal of clinical microbiology, 52(7), 2334-2339 (2014-04-18) Loss of Nrf2 in bone marrow-derived macrophages impairs antigen-driven CD8(+) T cell function by limiting GSH and Cys availability.Lisa K Sha et al.Free radical biology & medicine, 83, 77-88 (2015-02-18) The short- and long-term effects of orally administered high-dose reduced graphene oxide nanosheets on mouse behaviors.Ding Zhang et al.Biomaterials, 68, 100-113 (2015-08-16) Propensity for biofilm formation by clinical isolates from urinary tract infections: developing a multifactorial predictive model to improve antibiotherapy.Maria José Alves et al.Journal of medical microbiology, 63(Pt 3), 471-477 (2014-01-17) Amino acid analysis using chromatography-mass spectrometry: An inter platform comparison study.P Krumpochova et al.Journal of pharmaceutical and biomedical analysis, 114, 398-407 (2015-06-27) Methionine and cystine double deprivation stress suppresses glioma proliferation via inducing ROS/autophagy.Huailei Liu et al.Toxicology letters, 232(2), 349-355 (2014-12-03) A quantitative metabolomics peek into planarian regeneration.Nivedita Natarajan et al.The Analyst, 140(10), 3445-3464 (2015-03-31) Drug repurposing: sulfasalazine sensitizes gliomas to gamma knife radiosurgery by blocking cystine uptake through system Xc-, leading to glutathione depletion.L Sleire et al.Oncogene, 34(49), 5951-5959 (2015-03-24) Clinical utility of chitotriosidase enzyme activity in nephropathic cystinosis.Mohamed A Elmonem et al.Orphanet journal of rare diseases, 9, 155-155 (2014-11-20) Physiological Roles and Adverse Effects of the Two Cystine Importers of Escherichia coli.Karin R Chonoles Imlay et al.Journal of bacteriology, 197(23), 3629-3644 (2015-09-10) Cystine accumulation attenuates insulin release from the pancreatic β-cell due to elevated oxidative stress and decreased ATP levels.Bernadette McEvoy et al.The Journal of physiology, 593(23), 5167-5182 (2015-10-21) Biochemical and functional characterization of a periplasmic disulfide oxidoreductase from Neisseria meningitidis essential for meningococcal viability.Adeline Gand et al.The Biochemical journal, 468(2), 271-282 (2015-04-01) High-Throughput Assay Development for Cystine-Glutamate Antiporter (xc-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma Cells.Ajit G Thomas et al.PloS one, 10(8), e0127785-e0127785 (2015-08-08) Elevation of proteasomal substrate levels sensitizes cells to apoptosis induced by inhibition of proteasomal deubiquitinases.Chao Sun et al.PloS one, 9(10), e108839-e108839 (2014-10-07) A colorimetric sensor array for detection and discrimination of biothiols based on aggregation of gold nanoparticles.Forough Ghasemi et al.Analytica chimica acta, 882, 58-67 (2015-06-05) Disruption of Proline Synthesis in Melanoma Inhibits Protein Production Mediated by the GCN2 Pathway.Gregory R Kardos et al.Molecular cancer research : MCR, 13(10), 1408-1420 (2015-06-18) Dimeric and monomeric surfactants derived from sulfur-containing amino acids.Célia M C Faustino et al.Journal of colloid and interface science, 351(2), 472-477 (2010-08-31) Proteomic analysis of 3-MCPD and 3-MCPD dipalmitate toxicity in rat testis.Stefanie Sawada et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 83, 84-92 (2015-06-15) Common mutation causes cystinosis in the majority of black South African patients.E Patricia Owen et al.Pediatric nephrology (Berlin, Germany), 30(4), 595-601 (2014-10-19) Prevalence and Susceptibility Pattern of Multi Drug Resistant Clinical Isolates of Pseudomonas aeruginosa in Karachi.Fouzia Khan et al.Pakistan journal of medical sciences, 30(5), 951-954 (2014-09-17) Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support.Jeannette Boutter et al.Oncotarget, 5(22), 11501-11512 (2014-11-22) Capillary electrophoresis study on segment/segment system for segments based on phase of mixed micelles and its role in transport of particles between the two segments.Sławomir Oszwałdowski et al.Journal of chromatography. A, 1412, 139-150 (2015-08-25) Simultaneous determination of albumin and low-molecular-mass thiols in plasma by HPLC with UV detection.Kamila Borowczyk et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 981-982, 57-64 (2015-01-24) Dietary methionine can sustain cytosolic redox homeostasis in the mouse liver.Sofi Eriksson et al.Nature communications, 6, 6479-6479 (2015-03-21) Linking trace element variations with macronutrients and major cations in marine mussels Mytilus edulis and Perna viridis.Fengjie Liu et al.Environmental toxicology and chemistry, 34(9), 2041-2050 (2015-04-23) Yokukansan, a kampo medicine, protects PC12 cells from glutamate-induced death by augmenting gene expression of cystine/glutamate antiporter system Xc-.Hitomi Kanno et al.PloS one, 9(12), e116275-e116275 (2015-01-01) Cysteine oxidation impairs systemic glucocorticoid responsiveness in children with difficult-to-treat asthma.Susan T Stephenson et al.The Journal of allergy and clinical immunology, 136(2), 454-461 (2015-03-10) Skeletal muscle wasting occurs in adult rats under chronic treatment with paracetamol when glutathione-dependent detoxification is highly activated.C Mast et al.Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 65(5), 623-631 (2014-11-06) Effect of GABA on oxidative stress in the skeletal muscles and plasma free amino acids in mice fed high-fat diet.Z X Xie et al.Journal of animal physiology and animal nutrition, 99(3), 492-500 (2014-10-01)

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