Boiling point	152-154 ºC
Flash point	40 ºC
Density	0.99
Refractive index	1.5055-1.5075

Symbol(GHS)	Xi
Hazard Codes	R10;R36/37/38
SDS/MSDS	S16;S26;S37/39

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Dietary lipids fuel GPX4-restricted enteritis resembling Crohn's disease.Lisa Mayr et al.Nature communications, 11(1), 1775-1775 (2020-04-15) A 13-week subchronic toxicity study of hinokitiol administered in the diet to F344 rats.Y M Cho et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 49(8), 1782-1786 (2011-05-12) Zinc-dependent effects of small molecules on the insulin-sensitive transcription factor FOXO1a and gluconeogenic genes.Amy R Cameron et al.Metallomics : integrated biometal science, 2(3), 195-203 (2010-11-12) In vitro skin permeation of hinokitiol loaded in vesicles composed of behenyltrimethylammonium chloride and stearic acid.Xia Yang et al.Drug development and industrial pharmacy, 36(5), 556-562 (2010-02-10) Structural insights into the hot spot amino acid residues of mushroom tyrosinase for the bindings of thujaplicins.Satoshi Takahashi et al.Bioorganic & medicinal chemistry, 18(22), 8112-8118 (2010-10-16) Hinokitiol inhibits platelet activation ex vivo and thrombus formation in vivo.Kuan H Lin et al.Biochemical pharmacology, 85(10), 1478-1485 (2013-03-12) Hinokitiol, a natural tropolone derivative, inhibits TNF-alpha production in LPS-activated macrophages via suppression of NF-kappaB.Se Eun Byeon et al.Planta medica, 74(8), 828-833 (2008-06-10) In vivo hair growth promotion effects of cosmetic preparations containing hinokitiol-loaded poly(epsilon-caprolacton) nanocapsules.S L Hwang et al.Journal of microencapsulation, 25(5), 351-356 (2008-05-10) High production of beta-thujaplicin glycosides by immobilized plant cells of Nicotiana tabacum.S Kwon et al.Acta biologica Hungarica, 59(3), 347-355 (2008-10-09) Improved beta-thujaplicin production in Cupressus lusitanica suspension cultures by fungal elicitor and methyl jasmonate.J Zhao et al.Applied microbiology and biotechnology, 55(3), 301-305 (2001-05-09) Multiple signalling pathways mediate fungal elicitor-induced beta-thujaplicin biosynthesis in Cupressus lusitanica cell cultures.Jian Zhao et al.Journal of experimental botany, 54(383), 647-656 (2003-01-30) Anti-duck virus hepatitis mechanisms of Bush Sophora Root polysaccharide and its sulfate verified by intervention experiments.Yun Chen et al.Virus research, 204, 58-67 (2015-04-23) Hinokitiol activates the hypoxia-inducible factor (HIF) pathway through inhibition of HIF hydroxylases.Myong Jin Lee et al.Biochemical and biophysical research communications, 396(2), 370-375 (2010-04-27) Time-kill assay results for a linalool-hinokitiol-based eyelid cleanser for lid hygiene.Jeffrey P Gilbard et al.Cornea, 29(5), 559-563 (2010-03-24) In vitro and in vivo therapeutics of β-thujaplicin on LPS-induced inflammation in macrophages and septic shock in mice.M-F Shih et al.International journal of immunopathology and pharmacology, 25(1), 39-48 (2012-04-18) In vitro permeation study of hinokitiol: effects of vehicles and enhancers.Hyang Hee Joo et al.Drug delivery, 15(1), 19-22 (2008-01-17) Antifungal mechanism of hinokitiol against Candida albicans.Nami Komaki et al.Biological & pharmaceutical bulletin, 31(4), 735-737 (2008-04-02) Synthesis of tropolone derivatives and evaluation of their in vitro neuroprotective activity.Maria Koufaki et al.European journal of medicinal chemistry, 45(3), 1107-1112 (2010-01-05) Volatile and non-volatile monoterpenes produced by elicitor-stimulated Cupressus lusitanica cultured cells.Ransika De Alwis et al.Journal of plant physiology, 166(7), 720-728 (2008-11-26) High-performance liquid chromatography with dual-wavelength ultraviolet detection for measurement of hinokitiol in personal care products.Yasuhiko Higashi et al.Journal of cosmetic science, 60(5), 519-525 (2009-10-14) Stress-related activities induced by predator odor may become indistinguishable by hinokitiol odor.Toyotaka Murakami et al.Neuroreport, 23(18), 1071-1076 (2012-11-07) Antibacterial activity of beta-thujaplicin.T J Trust et al.Canadian journal of microbiology, 19(11), 1341-1346 (1973-11-01) Determination of hinokitiol in skin lotion by high-performance liquid chromatography-ultraviolet detection after precolumn derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole.Yasuhiko Higashi et al.Journal of cosmetic science, 64(5), 381-389 (2013-10-22) Preventive effects of β-thujaplicin against UVB-induced MMP-1 and MMP-3 mRNA expressions in skin fibroblasts.Jong Yuh Cherng et al.The American journal of Chinese medicine, 40(2), 387-398 (2012-03-16) Hinokitiol Inhibits Melanogenesis via AKT/mTOR Signaling in B16F10 Mouse Melanoma Cells.Yu-Tzu Tsao et al.International journal of molecular sciences, 17(2), 248-248 (2016-02-24) In vitro and in vivo anti-plasmodial activity of essential oils, including hinokitiol.Ryuichi Fujisaki et al.The Southeast Asian journal of tropical medicine and public health, 43(2), 270-279 (2012-10-23) Effects of a combination of hinokitiol (β-thujaplicin) and an organic acid mixture on ruminal fermentation in heifers fed a high-grain diet.Junichiro Ishii et al.Animal science journal = Nihon chikusan Gakkaiho, 83(1), 36-42 (2012-01-19) Antiviral activity of the zinc ionophores pyrithione and hinokitiol against picornavirus infections.B M Krenn et al.Journal of virology, 83(1), 58-64 (2008-10-17) The furan route to tropolones: probing the antiproliferative effects of β-thujaplicin analogs.E Zachary Oblak et al.Organic & biomolecular chemistry, 10(43), 8597-8604 (2012-10-04) p27-Associated G1 arrest induced by hinokitiol in human malignant melanoma cells is mediated via down-regulation of pRb, Skp2 ubiquitin ligase, and impairment of Cdk2 function.Shicheng Liu et al.Cancer letters, 286(2), 240-249 (2009-07-28) Inhibitory effects of hinokitiol on tyrosinase activity and melanin biosynthesis and its antimicrobial activities.Yu-Jing Zhu et al.Journal of enzyme inhibition and medicinal chemistry, 25(6), 798-803 (2010-06-29) Antifungal properties of ethanolic extract and its active compounds from Calocedrus macrolepis var. formosana (Florin) heartwood.Tsair-Bor Yen et al.Bioresource technology, 99(11), 4871-4877 (2007-11-06) Anti-inflammatory effects of hinokitiol on human corneal epithelial cells: an in vitro study.J Ye et al.Eye (London, England), 29(7), 964-971 (2015-05-09) Antibacterial effect of beta-thujaplicin on staphylococci isolated from atopic dermatitis: relationship between changes in the number of viable bacterial cells and clinical improvement in an eczematous lesion of atopic dermatitis.Yaeno Arima et al.The Journal of antimicrobial chemotherapy, 51(1), 113-122 (2002-12-21)

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