Boiling point	217-220 ºC
Flash point	89 ºC
Density	0.92
Refractive index	1.446

Symbol(GHS)	Xn
Hazard Codes	R22;R38
SDS/MSDS	S26;S36

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Characterization of two carnation petal prolyl 4 hydroxylases.Florina Vlad et al.Physiologia plantarum, 140(2), 199-207 (2010-06-18) Competitive inhibitors of the CphA metallo-beta-lactamase from Aeromonas hydrophila.L E Horsfall et al.Antimicrobial agents and chemotherapy, 51(6), 2136-2142 (2007-02-20) X-ray structure characterization of palladium(II) ternary complexes of pyridinedicarboxylic and phthalic acid with phenanthroline and bipyridine.Yue Wang et al.Chemical & pharmaceutical bulletin, 53(4), 366-373 (2005-04-02) Picolinate ruthenium(II)-arene complex with in vitro antiproliferative and antimetastatic properties: comparison to a series of ruthenium(II)-arene complexes with similar structure.Nevenka Gligorijević et al.Journal of inorganic biochemistry, 108, 53-61 (2012-01-24) Prolyl 4-hydroxylase, a target enzyme for drug development. Design of suppressive agents and the in vitro effects of inhibitors and proinhibitors.H M Hanauske-Abel Journal of hepatology, 13 Suppl 3, S8-15 (1991-01-01) Selective stabilization of HIF-1α in renal tubular cells by 2-oxoglutarate analogues.Gunnar Schley et al.The American journal of pathology, 181(5), 1595-1606 (2012-09-05) Pharmacological modulation of histone demethylase activity by a small molecule isolated from subcritical water extracts of Sasa senanensis leaves prolongs the lifespan of Drosophila melanogaster.Yuzo Nakagawa-Yagi et al.BMC complementary and alternative medicine, 12, 101-101 (2012-07-20) Small-molecule-based inhibition of histone demethylation in cells assessed by quantitative mass spectrometry.Mukram M Mackeen et al.Journal of proteome research, 9(8), 4082-4092 (2010-06-30) Competitive inhibition of glutamate dehydrogenase reaction.Rajarshi Choudhury et al.FEBS letters, 581(14), 2733-2736 (2007-05-29) Enabling lead discovery for histone lysine demethylases by high-throughput RapidFire mass spectrometry.Sue E Hutchinson et al.Journal of biomolecular screening, 17(1), 39-48 (2011-08-24) Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor.Line H Kristensen et al.The FEBS journal, 279(11), 1905-1914 (2012-03-17) Inhibition of prolyl hydroxylation and procollagen processing in chick-embryo calvaria by a derivative of pyridine-2,4-dicarboxylate. Characterization of the diethyl ester as a proinhibitor.G Tschank et al.The Biochemical journal, 275 ( Pt 2), 469-476 (1991-04-15) Inhibitors of 2-ketoglutarate-dependent dioxygenases block aspartyl beta-hydroxylation of recombinant human factor IX in several mammalian expression systems.C K Derian et al.The Journal of biological chemistry, 264(12), 6615-6618 (1989-04-25) The effectiveness of inhibitors of soluble prolyl hydroxylase against the enzyme in the cisternae of isolated bone microsomes.G Tschank et al.Archives of biochemistry and biophysics, 261(2), 312-323 (1988-03-01) The active site of an algal prolyl 4-hydroxylase has a large structural plasticity.M Kristian Koski et al.The Journal of biological chemistry, 282(51), 37112-37123 (2007-10-18) Oxidations of Benzhydrazide and Phenylacetic Hydrazide by Hexachloroiridate(IV): Reaction Mechanism and Structure-Reactivity Relationship.Xiaolai Zhang Molecules (Basel, Switzerland), 25(2) (2020-01-17) α-Ketoglutarate-related inhibitors of HIF prolyl hydroxylases are substrates of renal organic anion transporters 1 (OAT1) and 4 (OAT4).Yohannes Hagos et al.Pflugers Archiv : European journal of physiology, 464(4), 367-374 (2012-08-10) In vitro inhibition of collagen formation by 2,4-pyridine dicarboxylate and minoxidil in rabbit corneal fibroblasts.M Sharir et al.Current eye research, 12(6), 553-559 (1993-06-01) Self-referencing intensity measurements based on square-wave gated phase-modulation fluorimetry.H M Rowe et al.Applied spectroscopy, 57(5), 532-537 (2003-12-09) Pharmacologically induced angiogenesis in transgenic zebrafish.Michael Raghunath et al.Biochemical and biophysical research communications, 378(4), 766-771 (2008-12-11) Synthesis, characterization and fluorescence properties of novel pyridine dicarboxylic acid derivatives and corresponding Tb(III) complexes.Guo-liang Gu et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 71(1), 209-214 (2008-02-19) Ascorbate affects proliferation of guinea-pig vascular smooth muscle cells by direct and extracellular matrix-mediated effects.V O Ivanov et al.Journal of molecular and cellular cardiology, 29(12), 3293-3303 (1998-04-04) A red zwitterionic co-crystal of acetaminophen and 2,4-pyridinedicarboxylic acid.John R G Sander et al.Journal of pharmaceutical sciences, 99(9), 3676-3683 (2010-06-25) Chromatin-Mediated Reversible Silencing of Sense-Antisense Gene Pairs in Embryonic Stem Cells Is Consolidated upon Differentiation.Friedemann Loos et al.Molecular and cellular biology, 35(14), 2436-2447 (2015-05-13)

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