Boiling point	159 ºC
Flash point	150 ºF
Density	0.955
Refractive index	1.436

Symbol(GHS)	Xi
Hazard Codes	R36/37/38
SDS/MSDS	S26;S36/37/39;S45

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

E2F site in the essential promoter region does not confer S phase-specific transcription of the ABCC10 gene in human prostate cancer cells.Magdalena Dabrowska et al.Acta biochimica Polonica, 64(2), 371-374 (2017-06-15) Preparative scale isolation, purification and derivatization of mimosine, a non-proteinogenic amino acid.Kiyoshi Nokihara et al.Amino acids, 43(1), 475-482 (2011-10-14) miR-21 Protects Against Ischemia/Reperfusion-Induced Acute Kidney Injury by Preventing Epithelial Cell Apoptosis and Inhibiting Dendritic Cell Maturation.Nana Song et al.Frontiers in physiology, 9, 790-790 (2018-07-18) Neuronal apoptosis inhibitory protein (NAIP) localizes to the cytokinetic machinery during cell division.Francisco Abadía-Molina et al.Scientific reports, 7, 39981-39981 (2017-01-07) A Bio-inspired Hypoxia Sensor using HIF1a-Oxygen-Dependent Degradation Domain.Pablo Iglesias et al.Scientific reports, 9(1), 7117-7117 (2019-05-10) Mimosine, a plant-derived amino acid induces apoptosis in human pancreatic cancer xenografts.Attila Zalatnai et al.Anticancer research, 23(5A), 4007-4009 (2003-12-12) Productive performance and urinary excretion of mimosine metabolites by hair sheep grazing in a silvopastoral system with high densities of Leucaena leucocephala.Marcos Barros-Rodríguez et al.Tropical animal health and production, 44(8), 1873-1878 (2012-04-25) RNF169 limits 53BP1 deposition at DSBs to stimulate single-strand annealing repair.Liwei An et al.Proceedings of the National Academy of Sciences of the United States of America, 115(35), E8286-E8295 (2018-08-15) DDX3 localizes to the centrosome and prevents multipolar mitosis by epigenetically and translationally modulating p53 expression.Wei-Ju Chen et al.Scientific reports, 7(1), 9411-9411 (2017-08-27) Mimosine blocks cell cycle progression by chelating iron in asynchronous human breast cancer cells.K S Kulp et al.Toxicology and applied pharmacology, 139(2), 356-364 (1996-08-01) DNA Ligase 1 is an essential mediator of sister chromatid telomere fusions in G2 cell cycle phase.Kate Liddiard et al.Nucleic acids research, 47(5), 2402-2424 (2018-12-28) Curcumin provides potential protection against the activation of hypoxia and prolyl 4-hydroxylase inhibitors on prostate-specific antigen expression in human prostate carcinoma cells.Li-Chuan Chung et al.Molecular nutrition & food research, 55(11), 1666-1676 (2011-09-22) Xanthine oxidase/tyrosinase inhibiting, antioxidant, and antifungal oxindole alkaloids from Isatis costata.Ijaz Ahmad et al.Pharmaceutical biology, 48(6), 716-721 (2010-07-22) Prolyl hydroxylase inhibitors increase the production of vascular endothelial growth factor by periodontal fibroblasts.H Agis et al.Journal of periodontal research, 47(2), 165-173 (2011-10-01) The balance of beneficial and deleterious effects of hypoxia-inducible factor activation by prolyl hydroxylase inhibitor in rat remnant kidney depends on the timing of administration.Xiaofang Yu et al.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 27(8), 3110-3119 (2012-03-09) Phosphorylation of MCPH1 isoforms during mitosis followed by isoform-specific degradation by APC/C-CDH1.Stephanie K Meyer et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(2), 2796-2808 (2018-10-12) A comparative study on mimosine, 3,4-dihydroxy pyridone (3,4-DHP) and 2,3-dihydroxy pyridone (2,3-DHP), purine derivatives (PD) excretion in the urine, thyroid hormone and blood metabolites profiles of Thai swamp buffalo (Bubalus bubalis) and Murrah buffalo (Bubalus bubalis).Thongsuk Jetana et al.Tropical animal health and production, 44(4), 887-897 (2011-09-20) Mimosine, a plant-derived amino acid induces apoptosis in human pancreatic cancer xenografts.Zalatnai A and Bocsi J. Anticancer Research, 23(5A), 4007-4009 (2003) A gemcitabine sensitivity screen identifies a role for NEK9 in the replication stress response.Scott C Smith et al.Nucleic acids research, 42(18), 11517-11527 (2014-09-14) Inhibitory effect of mimosine on proliferation of human lung cancer cells is mediated by multiple mechanisms.H C Chang et al.Cancer letters, 145(1-2), 1-8 (1999-10-26) Microfluidic-assisted analysis of replicating DNA molecules.Julia M Sidorova et al.Nature protocols, 4(6), 849-861 (2009-05-16) Role for the thromboxane A2 receptor β-isoform in the pathogenesis of intrauterine growth restriction.Katie L Powell et al.Scientific reports, 6, 28811-28811 (2016-07-02) Single-Cell Quantification of Cytosine Modifications by Hyperspectral Dark-Field Imaging.Xiaolei Wang et al.ACS nano, 9(12), 11924-11932 (2015-10-28) Aurora B kinase inhibition in mitosis: strategies for optimising the use of aurora kinase inhibitors such as AT9283.Jayne Curry et al.Cell cycle (Georgetown, Tex.), 8(12), 1921-1929 (2009-05-15) Hypoxia-inducible factor-1α plays roles in Epstein-Barr virus's natural life cycle and tumorigenesis by inducing lytic infection through direct binding to the immediate-early BZLF1 gene promoter.Richard J Kraus et al.PLoS pathogens, 13(6), e1006404-e1006404 (2017-06-16) Mimosine is a cell-specific antagonist of folate metabolism.Oppenheim EW The Journal of Biological Chemistry, 275(25), 19268-19274 (2000) The novel function of JADE1S in cytokinesis of epithelial cells.Nirodhini S Siriwardana et al.Cell cycle (Georgetown, Tex.), 14(17), 2821-2834 (2015-07-08) Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice.Xing Shen et al.Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 27(10), 1298-1305 (2009-04-02) Daboia russelli venom hyaluronidase: purification, characterization and inhibition by β-3-(3-hydroxy-4-oxopyridyl) α-amino-propionic Acid.Y H Mahadeswaraswamy et al.Current topics in medicinal chemistry, 11(20), 2556-2565 (2011-06-21) Hypoxia and upregulation of hypoxia-inducible factor 1{alpha} stimulate venous thrombus recanalization.Colin Edward Evans et al.Arteriosclerosis, thrombosis, and vascular biology, 30(12), 2443-2451 (2010-10-12) HIF hydroxylase inhibitors decrease cellular oxygen consumption depending on their selectivity.Pascale Sulser et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(2), 2344-2358 (2020-01-08) L-mimosine and hypoxia can increase angiogenin production in dental pulp-derived cells.Klara Janjić et al.BMC oral health, 17(1), 87-87 (2017-05-27) miR-29c is downregulated in renal interstitial fibrosis in humans and rats and restored by HIF-α activation.Yi Fang et al.American journal of physiology. Renal physiology, 304(10), F1274-F1282 (2013-03-08) Oncogenic role of Merlin/NF2 in glioblastoma.P A Guerrero et al.Oncogene, 34(20), 2621-2630 (2014-07-22) Mimosine-induced apoptosis in C6 glioma cells requires the release of mitochondria-derived reactive oxygen species and p38, JNK activation.Shanlou Qiao et al.Neurochemical research, 37(2), 417-427 (2011-10-12) Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations.Henrike Johanna Gothe et al.Molecular cell, 75(2), 267-283 (2019-06-17) Identification of murine phosphodiesterase 5A isoforms and their functional characterization in HL-1 cardiac cell line.Federica Campolo et al.Journal of cellular physiology, 233(1), 325-337 (2017-03-02) YM155 inhibits topoisomerase function.Mei Hong et al.Anti-cancer drugs, 28(2), 142-152 (2016-10-19) Mimosine arrests proliferating human cells before onset of DNA replication in a dose-dependent manner.T Krude Experimental cell research, 247(1), 148-159 (1999-02-27) Cell cycle-regulated ubiquitination of tankyrase 1 by RNF8 and ABRO1/BRCC36 controls the timing of sister telomere resolution.Ekta Tripathi et al.The EMBO journal, 36(4), 503-519 (2016-12-21) Metal self-assembly mimosine peptides with enhanced antimicrobial activity: towards a new generation of multitasking chelating agents.Joanna Izabela Lachowicz et al.Dalton transactions (Cambridge, England : 2003), 49(9), 2862-2879 (2020-02-19) Upregulation of hypoxia-inducible factor 1 alpha in local vein wall is associated with enhanced venous thrombus resolution.Colin E Evans et al.Thrombosis research, 128(4), 346-351 (2011-05-31) Pretreatment with intracoronary mimosine improves postischemic myocardial functional recovery.Brandon Crowe et al.Surgery, 150(2), 191-196 (2011-08-02) Molecular dissection of the centrosome overduplication pathway in S-phase-arrested cells.Suzanna L Prosser et al.Molecular and cellular biology, 29(7), 1760-1773 (2009-01-14) Inhibitory effect of mimosine on polyphenoloxidase from cephalothoraxes of Pacific white shrimp (Litopenaeus vannamei).Nilesh Prakash Nirmal et al.Journal of agricultural and food chemistry, 59(18), 10256-10260 (2011-08-26) Formation of dehydroalanine from mimosine and cysteine: artifacts in gas chromatography/mass spectrometry based metabolomics.Young-Mo Kim et al.Rapid communications in mass spectrometry : RCM, 25(17), 2561-2564 (2011-09-14) Solid-phase synthesis of mimosine tetrapeptides and their inhibitory activities on neuraminidase and tyrosinase.Atul Upadhyay et al.Journal of agricultural and food chemistry, 59(24), 12858-12863 (2011-11-04) Inhibitory effect of l-mimosine on bleomycin-induced pulmonary fibrosis in rats: Role of eIF3a and p27.Xian-Wei Li et al.International immunopharmacology, 27(1), 53-64 (2015-05-10) Cell-cycle-dependences of membrane permeability and viability observed for HeLa cells undergoing multi-bubble-cell interactions.Pengfei Fan et al.Ultrasonics sonochemistry, 53, 178-186 (2019-01-16) L-Mimosine blocks cell proliferation via upregulation of B-cell translocation gene 2 and N-myc downstream regulated gene 1 in prostate carcinoma cells.Li-Chuan Chung et al.American journal of physiology. Cell physiology, 302(4), C676-C685 (2011-11-26) Identifying and targeting cancer-specific metabolism with network-based drug target prediction.Maria Pires Pacheco et al.EBioMedicine, 43, 98-106 (2019-05-28) N-myc downstream regulated gene1/Cap43 overexpression suppresses tumor growth by hepatic cancer cells through cell cycle arrest at the G0/G1 phase.Jun Akiba et al.Cancer letters, 310(1), 25-34 (2011-07-22) Contribution of condensed tannins and mimosine to the methane mitigation caused by feeding Leucaena leucocephala.Yosra A Soltan et al.Archives of animal nutrition, 67(3), 169-184 (2013-06-08) Mimosine arrests the cell cycle prior to the onset of DNA replication by preventing the binding of human Ctf4/And-1 to chromatin via Hif-1α activation in HeLa cells.Soon-Young Park et al.Cell cycle (Georgetown, Tex.), 11(4), 761-766 (2012-03-01) Cytometry of chromatin bound Mcm6 and PCNA identifies two states in G1 that are separated functionally by the G1 restriction point.Phyllis S Frisa et al.BMC cell biology, 11, 26-26 (2010-04-20) The identification of dual protective agents against cisplatin-induced oto- and nephrotoxicity using the zebrafish model.Jaime N Wertman et al.eLife, 9 (2020-07-29) Translational downregulation of HSP90 expression by iron chelators in neuroblastoma cells.Viktoryia Sidarovich et al.Molecular pharmacology, 87(3), 513-524 (2015-01-08) Effect of the compound L-mimosine in an in vivo model of chronic granuloma formation induced by potassium permanganate (KMNO4).Frydas S International Journal of Immunopathology and Pharmacology, 16(2), 99-104 (2003) S-phase Enriched Non-coding RNAs Regulate Gene Expression and Cell Cycle Progression.Ozlem Yildirim et al.Cell reports, 31(6), 107629-107629 (2020-05-14) Mimosine accumulation in Leucaena leucocephala in response to stress signaling molecules and acute UV exposure.Kelly Cristine da Silva Rodrigues-Corrêa et al.Plant physiology and biochemistry : PPB, 135, 432-440 (2018-11-30) Transgenic Leucaena leucocephala expressing the Rhizobium gene pydA encoding a meta-cleavage dioxygenase shows reduced mimosine content.Sandro L R Jube et al.Plant physiology and biochemistry : PPB, 48(4), 273-278 (2010-02-09) Mimosine blocks cell cycle progression by chelating iron in asynchronous human breast cancer cells.Kulp KS and Vulliet PR. Toxicology and Applied Pharmacology, 139(2), 356-364 (1996) Adam12 plays a role during uterine decidualization in mice.Li Zhang et al.Cell and tissue research, 338(3), 413-421 (2009-10-21) Transient hypoxia-inducible factor activation in rat renal ablation and reduced fibrosis with L-mimosine.Xiaofang Yu et al.Nephrology (Carlton, Vic.), 17(1), 58-67 (2011-07-23) LSD1 promotes S-phase entry and tumorigenesis via chromatin co-occupation with E2F1 and selective H3K9 demethylation.Y He et al.Oncogene, 37(4), 534-543 (2017-10-11) Linker histone variant H1T targets rDNA repeats.Ruiko Tani et al.Epigenetics, 11(4), 288-302 (2016-03-29) Epigenetic Changes during Hepatic Stellate Cell Activation.Silke Götze et al.PloS one, 10(6), e0128745-e0128745 (2015-06-13) Compounds that target host cell proteins prevent varicella-zoster virus replication in culture, ex vivo, and in SCID-Hu mice.Jenny Rowe et al.Antiviral research, 86(3), 276-285 (2010-03-24) Mimosine is a cell-specific antagonist of folate metabolism.E W Oppenheim et al.The Journal of biological chemistry, 275(25), 19268-19274 (2000-04-15) Hypoxia-inducible factor-1α inhibition modulates airway hyperresponsiveness and nitric oxide levels in a BALB/c mouse model of asthma.Carola Dewitz et al.Clinical immunology (Orlando, Fla.), 176, 94-99 (2017-01-18) Retinoids Enhance the Expression of Cathelicidin Antimicrobial Peptide during Reactive Dermal Adipogenesis.Marc C Liggins et al.Journal of immunology (Baltimore, Md. : 1950), 203(6), 1589-1597 (2019-08-20) Human NOC3 is essential for DNA replication licensing in human cells.Man-Hei Cheung et al.Cell cycle (Georgetown, Tex.), 18(5), 605-620 (2019-02-12)

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