Melting point	-70 ºC
Water Solubility	Miscible
Boiling point	194 ºC
Flash point	83 ºC
Density	1.01
Refractive index	1.425-1.427

Symbol(GHS)	Xn
Hazard Codes	R63
SDS/MSDS	S36/37

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

More

Name	CAS

More

Articles

Peer-Reviewed Papers

Modulation of nicotinic receptor channels by adrenergic stimulation in rat pinealocytes.Jin-Young Yoon et al.American journal of physiology. Cell physiology, 306(8), C726-C735 (2014-02-21) Activation of presynaptic GABA(B(1a,2)) receptors inhibits synaptic transmission at mammalian inhibitory cholinergic olivocochlear-hair cell synapses.Carolina Wedemeyer et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(39), 15477-15487 (2013-09-27) GluN2D-containing NMDA receptors inhibit neurotransmission in the mouse striatum through a cholinergic mechanism: implication for Parkinson's disease.Xiaoqun Zhang et al.Journal of neurochemistry, 129(4), 581-590 (2014-01-31) Quantal and non-quantal acetylcholine release at neuromuscular junctions of muscles of different types in a model of hypogravity.O V Tyapkina et al.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 448, 4-6 (2013-03-13) Identification of distinct ChAT⁺ neurons and activity-dependent control of postnatal SVZ neurogenesis.Patricia Paez-Gonzalez et al.Nature neuroscience, 17(7), 934-942 (2014-06-02) The nicotinic α5 subunit can replace either an acetylcholine-binding or nonbinding subunit in the α4β2* neuronal nicotinic receptor.Xiaochun Jin et al.Molecular pharmacology, 85(1), 11-17 (2013-11-05) [Role of serine/threonine and tyrosine protein phosphatases in command Helix lucorum neurons at the cellular correlate of habituation].A S Pivovarov et al.Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova, 63(2), 256-268 (2013-07-23) Bedside to bench: role of muscarinic receptor activation in ultrarapid growth of colorectal cancer in a patient with pheochromocytoma.Erik C von Rosenvinge et al.Mayo Clinic proceedings, 88(11), 1340-1346 (2013-10-09) The transcription factor Hmx1 and growth factor receptor activities control sympathetic neurons diversification.Alessandro Furlan et al.The EMBO journal, 32(11), 1613-1625 (2013-04-18) Two distinct allosteric binding sites at α4β2 nicotinic acetylcholine receptors revealed by NS206 and NS9283 give unique insights to binding activity-associated linkage at Cys-loop receptors.Jeppe A Olsen et al.The Journal of biological chemistry, 288(50), 35997-36006 (2013-10-31) Muscarinic M₃ receptors contribute to allergen-induced airway remodeling in mice.Loes E M Kistemaker et al.American journal of respiratory cell and molecular biology, 50(4), 690-698 (2013-10-26) In vivo and in vitro effects of neostigmine on gastrointestinal tract motility of horses.Jorge E Nieto et al.American journal of veterinary research, 74(4), 579-588 (2013-03-28) δ-opioid and dopaminergic processes in accumbens shell modulate the cholinergic control of predictive learning and choice.Vincent Laurent et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(4), 1358-1369 (2014-01-24) Persistent sodium current drives conditional pacemaking in CA1 pyramidal neurons under muscarinic stimulation.Jason Yamada-Hanff et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(38), 15011-15021 (2013-09-21) Rotational-resonance distance measurements in multi-spin systems.Aswin Verhoeven et al.Journal of magnetic resonance (San Diego, Calif. : 1997), 168(2), 314-326 (2004-05-14) Free energy, precision and learning: the role of cholinergic neuromodulation.Rosalyn J Moran et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(19), 8227-8236 (2013-05-10) Response.Ashbeel Roy et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(1), 2-3 (2014-01-05) Genetic dissection of the vav2-rac1 signaling axis in vascular smooth muscle cells.Salvatore Fabbiano et al.Molecular and cellular biology, 34(24), 4404-4419 (2014-10-08) A novel α4/7-conotoxin LvIA from Conus lividus that selectively blocks α3β2 vs. α6/α3β2β3 nicotinic acetylcholine receptors.Sulan Luo et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(4), 1842-1853 (2014-01-09) Coronary artery spasm as a cause of angina.Scott Kinlay Circulation, 129(17), 1717-1719 (2014-02-28) Tocotrienol Rich Palm Oil Extract Is More Effective Than Pure Tocotrienols at Improving Endothelium-Dependent Relaxation in the Presence of Oxidative Stress.Saher F Ali et al.Oxidative medicine and cellular longevity, 2015, 150829-150829 (2015-06-16) Skeletal muscle calpain acts through nitric oxide and neural miRNAs to regulate acetylcholine release in motor nerve terminals.Haipeng Zhu et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(17), 7308-7324 (2013-04-26) [Changes in pulmonary arteries dilatation reserve during chronic obstructive pulmonary disease model formation].N A Kuzubova et al.Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 99(2), 230-237 (2013-05-09) Fast modulation of visual perception by basal forebrain cholinergic neurons.Lucas Pinto et al.Nature neuroscience, 16(12), 1857-1863 (2013-10-29) Cholinergic control over attention in rats prone to attribute incentive salience to reward cues.Giovanna Paolone et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(19), 8321-8335 (2013-05-10) A novel acetylcholine bioensor and its electrochemical behavior.Wei Wang et al.Journal of biomedical nanotechnology, 9(4), 736-740 (2013-04-30) Decreased Kv1.5 expression in intrauterine growth retardation rats with exaggerated pulmonary hypertension.Ying Lv et al.American journal of physiology. Lung cellular and molecular physiology, 305(11), L856-L865 (2013-10-01) Depressed excitability and ion currents linked to slow exocytotic fusion pore in chromaffin cells of the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.Enrique Calvo-Gallardo et al.American journal of physiology. Cell physiology, 308(1), C1-19 (2014-11-08) Decrease in neuronal nicotinic acetylcholine receptor subunit and PSD-93 transcript levels in the male mouse MPG after cavernous nerve injury or explant culture.Beatrice M Girard et al.American journal of physiology. Renal physiology, 305(10), F1504-F1512 (2013-09-21) Letters to the editor: Cardiomyocyte-secreted acetylcholine.Achilles Pappano FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(1), 1-2 (2014-01-05) Differential modulation of spontaneous and evoked thalamocortical network activity by acetylcholine level in vitro.Jason C Wester et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(45), 17951-17966 (2013-11-08) Cannabidiol improves vasorelaxation in Zucker diabetic fatty rats through cyclooxygenase activation.Amanda J Wheal et al.The Journal of pharmacology and experimental therapeutics, 351(2), 457-466 (2014-09-13) Endothelial nitric oxide synthase uncoupling and microvascular dysfunction in the mesentery of mice deficient in α-galactosidase A.Justin J Kang et al.American journal of physiology. Gastrointestinal and liver physiology, 306(2), G140-G146 (2013-11-16) [Sex difference of functional and structural alterations in the myocardium of rats with hypothyroidism].M R Khara et al.Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 59(2), 18-22 (2013-07-05) Axon targeting of the alpha 7 nicotinic receptor in developing hippocampal neurons by Gprin1 regulates growth.Jacob C Nordman et al.Journal of neurochemistry, 129(4), 649-662 (2013-12-20) Revealing of T-type low-voltage activated calcium channels (CaV3) in frog neuromuscular junctions.L F Nurullin et al.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 449, 73-75 (2013-05-09) Medial septum-diagonal band of Broca (MSDB) GABAergic regulation of hippocampal acetylcholine efflux is dependent on cognitive demands.Jessica J Roland et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(2), 506-514 (2014-01-10) Acetylcholine controls GABA-, glutamate-, and glycine-dependent giant depolarizing potentials that govern spontaneous motoneuron activity at the onset of synaptogenesis in the mouse embryonic spinal cord.Antonny Czarnecki et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(18), 6389-6404 (2014-05-03) Prefrontal cholinergic mechanisms instigating shifts from monitoring for cues to cue-guided performance: converging electrochemical and fMRI evidence from rats and humans.William M Howe et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(20), 8742-8752 (2013-05-17) Accentuation of ursolic acid on muscarinic receptor-induced ANP secretion in beating rabbit atria.Hye Yoom Kim et al.Life sciences, 94(2), 145-150 (2013-12-18) Postsynaptic activity reverses the sign of the acetylcholine-induced long-term plasticity of GABAA inhibition.Soledad Domínguez et al.Proceedings of the National Academy of Sciences of the United States of America, 111(26), E2741-E2750 (2014-06-19) Role of aromatase in sex-specific cerebrovascular endothelial function in mice.Kristen L Zuloaga et al.American journal of physiology. Heart and circulatory physiology, 306(7), H929-H937 (2014-02-11) Silver nanoparticles induce anti-proliferative effects on airway smooth muscle cells. Role of nitric oxide and muscarinic receptor signaling pathway.Manuel A Ramírez-Lee et al.Toxicology letters, 224(2), 246-256 (2013-11-06) Interaction between substrates suggests a relationship between organophosphorus-sensitive phenylvalerate- and acetylcholine-hydrolyzing activities in chicken brain.Mónica Benabent et al.Toxicology letters, 230(2), 132-138 (2014-03-01) VPAC1 receptors regulate intestinal secretion and muscle contractility by activating cholinergic neurons in guinea pig jejunum.Candice Fung et al.American journal of physiology. Gastrointestinal and liver physiology, 306(9), G748-G758 (2014-03-01) Flagellin/TLR5 signaling potentiates airway serous secretion from swine tracheal submucosal glands.Soshi Muramatsu et al.American journal of physiology. Lung cellular and molecular physiology, 305(11), L819-L830 (2013-10-08) Role of endogenous vascular endothelial growth factor in endothelium-dependent vasodilation in humans.Anna M J Thijs et al.Hypertension (Dallas, Tex. : 1979), 61(5), 1060-1065 (2013-03-20) ACR-12 ionotropic acetylcholine receptor complexes regulate inhibitory motor neuron activity in Caenorhabditis elegans.Hilary A Petrash et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(13), 5524-5532 (2013-03-29) Hyperactivation of B-type motor neurons results in aberrant synchrony of the Caenorhabditis elegans motor circuit.Yingchuan B Qi et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(12), 5319-5325 (2013-03-22) Metformin ameliorates ovariectomy-induced vascular dysfunction in non-diabetic Wistar rats.Oliveira PW, de Sousa GJ, Caliman IF, et al. Clinical Science, 127(4), 265-275 (2014) Influence of gαq on the dynamics of m3-acetylcholine receptor-g-protein-coupled receptor kinase 2 interaction.Valerie Wolters et al.Molecular pharmacology, 87(1), 9-17 (2014-10-16) Effect of inhaled MgSO4 on FEV1 and PEF in children with asthma induced by acetylcholine: a randomized controlled clinical trail of 330 cases.Y X Sun et al.Journal of tropical pediatrics, 60(2), 141-147 (2013-12-18) Positive feedback regulation of agonist-stimulated endothelial Ca2+ dynamics by KCa3.1 channels in mouse mesenteric arteries.Xun Qian et al.Arteriosclerosis, thrombosis, and vascular biology, 34(1), 127-135 (2013-11-02) Acetylcholine encodes long-lasting presynaptic plasticity at glutamatergic synapses in the dorsal striatum after repeated amphetamine exposure.Wengang Wang et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(25), 10405-10426 (2013-06-21) IL-17A modulates oxidant stress-induced airway hyperresponsiveness but not emphysema.Mariona Pinart et al.PloS one, 8(3), e58452-e58452 (2013-03-19) Vascular injury in diabetic db/db mice is ameliorated by atorvastatin: role of Rac1/2-sensitive Nox-dependent pathways.Thiago Bruder-Nascimento et al.Clinical science (London, England : 1979), 128(7), 411-423 (2014-11-02) Vasoactive effects of prostaglandins from the perivascular fat of mesenteric resistance arteries in WKY and SHROB rats.Yolanda Mendizábal et al.Life sciences, 93(25-26), 1023-1032 (2013-11-10) Layer-specific interference with cholinergic signaling in the prefrontal cortex by smoking concentrations of nicotine.Rogier B Poorthuis et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(11), 4843-4853 (2013-03-15) Acute and chronic effects of botulinum neurotoxin a on the mammalian neuromuscular junction.Padmamalini Baskaran et al.Muscle & nerve, 50(2), 206-215 (2013-11-13) Dynamics of hippocampal acetylcholine release during lithium-pilocarpine-induced status epilepticus in rats.Markus H Hillert et al.Journal of neurochemistry, 131(1), 42-52 (2014-06-10) Experimental evidence and mathematical modeling of thermal effects on human colonic smooth muscle contractility.A Altomare et al.American journal of physiology. Gastrointestinal and liver physiology, 307(1), G77-G88 (2014-05-17) Reduction of angiotensin A and alamandine vasoactivity in the rabbit model of atherogenesis: differential effects of alamandine and Ang(1-7).Belthrand Habiyakare et al.International journal of experimental pathology, 95(4), 290-295 (2014-06-24) Grid-layout and theta-modulation of layer 2 pyramidal neurons in medial entorhinal cortex.Saikat Ray et al.Science (New York, N.Y.), 343(6173), 891-896 (2014-01-25) Evidence for encoding versus retrieval scheduling in the hippocampus by theta phase and acetylcholine.Vincent Douchamps et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(20), 8689-8704 (2013-05-17) Hypercontractility of intestinal longitudinal smooth muscle induced by cytokines is mediated by the nuclear factor-κB/AMP-activated kinase/myosin light chain kinase pathway.Ancy D Nalli et al.The Journal of pharmacology and experimental therapeutics, 350(1), 89-98 (2014-04-29) Effect of hyperpolarization-activated current I(f) on robustness of sinoatrial node pacemaking: theoretical study on influence of intracellular Na(+) concentration.Yasutaka Kurata et al.American journal of physiology. Heart and circulatory physiology, 304(10), H1337-H1351 (2013-03-19) Probing structural requirements of positive allosteric modulators of the M4 muscarinic receptor.Tracey Huynh et al.Journal of medicinal chemistry, 56(20), 8196-8200 (2013-10-01) Isolation of canine coronary sinus musculature from the atria by radiofrequency catheter ablation prevents induction of atrial fibrillation.Hiroshi Morita et al.Circulation. Arrhythmia and electrophysiology, 7(6), 1181-1188 (2014-11-09) Where attention falls: Increased risk of falls from the converging impact of cortical cholinergic and midbrain dopamine loss on striatal function.Martin Sarter et al.Experimental neurology, 257, 120-129 (2014-05-09) Chemerin reduces vascular nitric oxide/cGMP signalling in rat aorta: a link to vascular dysfunction in obesity?Neves KB, Lobato NS, Lopes RA, et al. Clinical Science, 127(2), 111-122 (2014) Selective potentiation of (α4)3(β2)2 nicotinic acetylcholine receptors augments amplitudes of prefrontal acetylcholine- and nicotine-evoked glutamatergic transients in rats.Morten Grupe et al.Biochemical pharmacology, 86(10), 1487-1496 (2013-09-21) [The role of spinal motoneurons in the mechanisms of hypogravitational motor syndrome development].R R Islamov et al.Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 99(3), 281-293 (2013-06-26) Vagal stimulation triggers peripheral vascular protection through the cholinergic anti-inflammatory pathway in a rat model of myocardial ischemia/reperfusion.Ming Zhao et al.Basic research in cardiology, 108(3), 345-345 (2013-03-23) [Diplopia following subcutaneous injections of botulinum toxin for cosmetic or medical use].Shira Sheen-Ophir et al.Harefuah, 152(2), 98-100 (2013-03-22) Elimination of vitamin D receptor in vascular endothelial cells alters vascular function.Ni W, Watts SW, Ng M, et al. Hypertension, 64(6), 1290-1298 (2014) Long-term effect of prazosin and losartan administration on blood pressure, heart, carotid artery, and acetylcholine induced dilation of cardiovascular system of young Wistar rats and SHR.Frantisek Kristek et al.General physiology and biophysics, 32(2), 235-243 (2013-05-18) Nicotinic acetylcholine receptors in attention circuitry: the role of layer VI neurons of prefrontal cortex.Eliane Proulx et al.Cellular and molecular life sciences : CMLS, 71(7), 1225-1244 (2013-10-15) Involvement of the ganglion cholinergic receptors in gonadotropin-releasing hormone, catecholamines, and progesterone release in the rat ovary.Cristina Daneri et al.Fertility and sterility, 99(7), 2062-2070 (2013-03-23) Vascular structure and function in the medial collateral ligament of anterior cruciate ligament transected rabbit knees.Daniel Miller et al.Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 32(9), 1104-1110 (2014-06-10) Cholinergic left-right asymmetry in the habenulo-interpeduncular pathway.Elim Hong et al.Proceedings of the National Academy of Sciences of the United States of America, 110(52), 21171-21176 (2013-12-12) Role of nitric oxide synthase isoforms for ophthalmic artery reactivity in mice.Panagiotis Laspas et al.Experimental eye research, 127, 1-8 (2014-07-16) Clinical usefulness, angiographic characteristics, and safety evaluation of intracoronary acetylcholine provocation testing among 921 consecutive white patients with unobstructed coronary arteries.Peter Ong et al.Circulation, 129(17), 1723-1730 (2014-02-28) Inhibition of bone morphogenic protein 4 restores endothelial function in db/db diabetic mice.Yang Zhang et al.Arteriosclerosis, thrombosis, and vascular biology, 34(1), 152-159 (2013-11-10) Stoichiometry for activation of neuronal α7 nicotinic receptors.Natalia Andersen et al.Proceedings of the National Academy of Sciences of the United States of America, 110(51), 20819-20824 (2013-12-04)

Remarks