Melting point	-45.1 ºC**
Boiling point	208 ºC***
Flash point	60.5±6.3 ºC, 计算值*
Density	0.8894 g/cm3 (20 ºC)**
Refractive index	1.4300 (589.3 nm 20 ºC)****

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Source	SDS/MSDS Samples
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Articles

Peer-Reviewed Papers

Hydroxytyrosol protects against oxidative DNA damage in human breast cells.Fernando Warleta et al.Nutrients, 3(10), 839-857 (2012-01-19) Carbonic anhydrase inhibitors. Identification of selective inhibitors of the human mitochondrial isozymes VA and VB over the cytosolic isozymes I and II from a natural product-based phenolic library.Rohan A Davis et al.Bioorganic & medicinal chemistry, 18(1), 14-18 (2009-12-08) Anti-hyperlipidemic and anti-atherosclerotic effects of Pinus eldarica Medw. nut in hypercholesterolemic rabbits.Hasan Fallah Huseini et al.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 23, 32-32 (2015-06-10) Protection of LDL from oxidation by olive oil polyphenols is associated with a downregulation of CD40-ligand expression and its downstream products in vivo in humans.Olga Castañer et al.The American journal of clinical nutrition, 95(5), 1238-1244 (2012-03-24) Characterization of polyketide metabolites from foliar endophytes of Picea glauca.Mark W Sumarah et al.Journal of natural products, 71(8), 1393-1398 (2008-07-19) Enzymatic alkylsuccinylation of tyrosol: Synthesis, characterization and property evaluation as a dual-functional antioxidant.Silvia Marzocchi et al.Food chemistry, 246, 108-114 (2018-01-03) Simultaneous determination of oleuropein and its metabolites in plasma by high-performance liquid chromatography.Anthony Tsarbopoulos et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 785(1), 157-164 (2003-01-22) Evaluation of tyrosol and farnesol as inducer in pigment production by Monascus purpureus ATCC16365.Seval Erkaya et al.Journal of basic microbiology, 60(8), 669-678 (2020-05-26) Automated method for determination of olive oil phenols and metabolites in human plasma and application in intervention studies.M I Orozco-Solano et al.Journal of chromatography. A, 1258, 108-116 (2012-09-05) Analysis of total contents of hydroxytyrosol and tyrosol in olive oils.Concepción Romero et al.Journal of agricultural and food chemistry, 60(36), 9017-9022 (2012-08-29) Evaluation of anti-platelet activity of grape pomace extracts.Maria Choleva et al.Food & function, 10(12), 8069-8080 (2019-11-26) Forecasting structure of natural products through color formation process by thin layer chromatography.Lujing Xu et al.Food chemistry, 334, 127496-127496 (2020-07-28) Direct liquid chromatography method for the simultaneous quantification of hydroxytyrosol and tyrosol in red wines.Zulema Piñeiro et al.Journal of agricultural and food chemistry, 59(21), 11683-11689 (2011-09-29) Protective effects of Merlot red wine extract and its major polyphenols in PC12 cells under oxidative stress conditions.Sara Martín et al.Journal of food science, 78(1), H112-H118 (2013-01-03) Determination of hydroxytyrosol and tyrosol by liquid chromatography for the quality control of cosmetic products based on olive extracts.Pablo Miralles et al.Journal of pharmaceutical and biomedical analysis, 102, 157-161 (2014-10-04) Engineering of a tyrosol-producing pathway, utilizing simple sugar and the central metabolic tyrosine, in Escherichia coli.Yasuharu Satoh et al.Journal of agricultural and food chemistry, 60(4), 979-984 (2012-01-10) A High-Throughput UHPLC-QqQ-MS Method for Polyphenol Profiling in Rosé Wines.Marine Lambert et al.Molecules (Basel, Switzerland), 20(5), 7890-7914 (2015-05-06) Tyrosol exerts a protective effect against dopaminergic neuronal cell death in in vitro model of Parkinson's disease.Pradeep Dewapriya et al.Food chemistry, 141(2), 1147-1157 (2013-06-26) Alcohol-based quorum sensing plays a role in adhesion and sliding motility of the yeast Debaryomyces hansenii.Klaus Gori et al.FEMS yeast research, 11(8), 643-652 (2011-11-19) Olive oil phenolics are dose-dependently absorbed in humans.F Visioli et al.FEBS letters, 468(2-3), 159-160 (2000-02-29) Extraction of 2-(4-hydroxyphenyl) ethanol from aqueous solution by emulsion liquid membranes.Reis MTA, et al. Journal of Membrane Science, 269(1), 161-170 (2006) Olive oil phenolics: effects on DNA oxidation and redox enzyme mRNA in prostate cells.José L Quiles et al.The British journal of nutrition, 88(3), 225-234 (2002-09-05) Effect of different aging techniques on the polysaccharide and phenolic composition and sensory characteristics of Syrah red wines fermented using different yeast strains.Rubén del Barrio-Galán et al.Food chemistry, 179, 116-126 (2015-02-28) Characterization of antimicrobial activities of olive phenolics on yeasts using conventional methods and mid-infrared spectroscopy.Canan Canal et al.Journal of food science and technology, 56(1), 149-158 (2019-02-08) Capillary gas chromatography-mass spectrometry quantitative determination of hydroxytyrosol and tyrosol in human urine after olive oil intake.E Miró-Casas et al.Analytical biochemistry, 294(1), 63-72 (2001-06-20) Authentication of Greek PDO Kalamata Table Olives: A Novel Non-Target High Resolution Mass Spectrometric Approach.Natasa P Kalogiouri et al.Molecules (Basel, Switzerland), 25(12) (2020-07-01) Squalene ameliorates atherosclerotic lesions through the reduction of CD36 scavenger receptor expression in macrophages.Sergio Granados-Principal et al.Molecular nutrition & food research, 56(5), 733-740 (2012-06-01) Natural product-based phenols as novel probes for mycobacterial and fungal carbonic anhydrases.Rohan A Davis et al.Journal of medicinal chemistry, 54(6), 1682-1692 (2011-02-22) Synthesis of lipophilic tyrosyl esters derivatives and assessment of their antimicrobial and antileishmania activities.Imen Aissa et al.Lipids in health and disease, 11, 13-13 (2012-01-24) Ultrasonic extraction of phenols from olive mill wastewater: comparison with conventional methods.Tina Jerman Klen et al.Journal of agricultural and food chemistry, 59(24), 12725-12731 (2011-11-08) Assay of tyrosol and hydroxytyrosol in olive oil by tandem mass spectrometry and isotope dilution method.Fabio Mazzotti et al.Food chemistry, 135(3), 1006-1010 (2012-09-08) Carbon nanotubes supported tyrosinase in the synthesis of lipophilic hydroxytyrosol and dihydrocaffeoyl catechols with antiviral activity against DNA and RNA viruses.Giorgia Botta et al.Bioorganic & medicinal chemistry, 23(17), 5345-5351 (2015-08-12) Tyrosol, a main phenol present in extra virgin olive oil, increases lifespan and stress resistance in Caenorhabditis elegans.Ana Cañuelo et al.Mechanisms of ageing and development, 133(8), 563-574 (2012-07-25) Multivariate approach to assess the chemical composition of Italian virgin olive oils as a function of variety and harvest period.Pierfrancesco Deiana et al.Food chemistry, 300, 125243-125243 (2019-07-30) Mechanism of action of Rhodiola, salidroside, tyrosol and triandrin in isolated neuroglial cells: an interactive pathway analysis of the downstream effects using RNA microarray data.Alexander Panossian et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 21(11), 1325-1348 (2014-08-31) Enzymatic routes for the production of mono- and di-glucosylated derivatives of hydroxytyrosol.Antonio Trincone et al.Bioresource technology, 115, 79-83 (2011-11-19) Host-pathogen interaction and signaling molecule secretion are modified in the dpp3 knockout mutant of Candida lusitaniae.Ayman Sabra et al.Infection and immunity, 82(1), 413-422 (2013-11-06) Bioavailability of tyrosol, an antioxidant phenolic compound present in wine and olive oil, in humans.M I Covas et al.Drugs under experimental and clinical research, 29(5-6), 203-206 (2004-05-12) Phenolic Profiling of Olives and Olive Oil Process-Derived Matrices Using UPLC-DAD-ESI-QTOF-HRMS Analysis.Tina Jerman Klen et al.Journal of agricultural and food chemistry, 63(15), 3859-3872 (2015-03-19) Endogenous enzymes involved in the transformation of oleuropein in Spanish table olive varieties.Eva Ramírez et al.Journal of agricultural and food chemistry, 62(39), 9569-9575 (2014-09-12) Self-Assembly of Catecholic Moiety-Containing Cationic Random Acrylic Copolymers.Vincenzo Taresco et al.The journal of physical chemistry. B, 119(26), 8369-8379 (2015-06-16) The MAP Kinase SsKpp2 Is Required for Mating/Filamentation in Sporisorium scitamineum.Yi Zhen Deng et al.Frontiers in microbiology, 9, 2555-2555 (2018-11-13) Valence structures of aromatic bioactive compounds: a combined theoretical and experimental study.Anoja Pushpamali Wickrama Arachchilage et al.Journal of synchrotron radiation, 19(Pt 5), 773-781 (2012-08-18) Degradation of model olive mill contaminants of OMW catalysed by zero-valent iron enhanced with a chelant.Irama Sanchez et al.Journal of hazardous materials, 199-200, 328-335 (2011-11-29) Effect of selected Saccharomyces cerevisiae yeast strains and different aging techniques on the polysaccharide and polyphenolic composition and sensorial characteristics of Cabernet Sauvignon red wines.Rubén del Barrio-Galán et al.Journal of the science of food and agriculture, 95(10), 2132-2144 (2014-09-27) Indole derivatives from a marine sponge-derived yeast as DPPH radical scavengers.Yasumasa Sugiyama et al.Journal of natural products, 72(11), 2069-2071 (2009-12-01) Application of an advanced and wide scope non-target screening workflow with LC-ESI-QTOF-MS and chemometrics for the classification of the Greek olive oil varieties.Natasa P Kalogiouri et al.Food chemistry, 256, 53-61 (2018-04-03) Salidroside and tyrosol from Rhodiola protect H9c2 cells from ischemia/reperfusion-induced apoptosis.Liwei Sun et al.Life sciences, 91(5-6), 151-158 (2012-07-10) Tyrosol, a phenolic compound, ameliorates hyperglycemia by regulating key enzymes of carbohydrate metabolism in streptozotocin induced diabetic rats.Ramasamy Chandramohan et al.Chemico-biological interactions, 229, 44-54 (2015-02-03) Olive fermentation brine: biotechnological potentialities and valorization.Imen Fendri et al.Environmental technology, 34(1-4), 181-193 (2013-03-28) [The study of the secondary metabolites from fungus Paecilomyces sp].Yong-Gang Zhang et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 34(5), 707-709 (2011-10-01) Removal of tyrosol from water by adsorption on carbonaceous materials and electrochemical advanced oxidation processes.Nelly Flores et al.Chemosphere, 201, 807-815 (2018-03-20) Evaluation of multi-starter S. cerevisiae/ D. bruxellensis cultures for mimicking and accelerating transformations occurring during barrel ageing of beer.Eduardo Coelho et al.Food chemistry, 323, 126826-126826 (2020-04-27) Screening of Commercial Enzymes for Transfructosylation of Tyrosol: Effect of Process Conditions and Reaction Network.Veronika Hollá et al.Biotechnology journal, 14(8), e1800571-e1800571 (2019-03-31) Antimicrobial and antioxidant amphiphilic random copolymers to address medical device-centered infections.Vincenzo Taresco et al.Acta biomaterialia, 22, 131-140 (2015-04-29) Impact of functional properties and release kinetics on antioxidant activity of biopolymer active films and coatings.Nasreddine Benbettaïeb et al.Food chemistry, 242, 369-377 (2017-10-19) Overexpression of the Trichoderma brevicompactum tri5 gene: effect on the expression of the trichodermin biosynthetic genes and on tomato seedlings.Anamariela Tijerino et al.Toxins, 3(9), 1220-1232 (2011-11-10) Differential anti-inflammatory effects of phenolic compounds from extra virgin olive oil identified in human whole blood cultures.Elizabeth A Miles et al.Nutrition (Burbank, Los Angeles County, Calif.), 21(3), 389-394 (2005-03-31) Quorum sensing in fungi: Q&A.Hiten D Madhani PLoS pathogens, 7(10), e1002301-e1002301 (2011-11-03) Multicommuted flow injection method for fast photometric determination of phenolic compounds in commercial virgin olive oil samples.Felipe J Lara-Ortega et al.Talanta, 147, 531-536 (2015-11-26) Olive phenolic compounds: metabolic and transcriptional profiling during fruit development.Fiammetta Alagna et al.BMC plant biology, 12, 162-162 (2012-09-12) [Studies on the secondary metabolites of Coriolopsis sp. G066].Zhi-gao Sang et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 34(4), 549-551 (2011-08-04) Use of solar distillation for olive mill wastewater drying and recovery of polyphenolic compounds.Sotirios Sklavos et al.Journal of environmental management, 162, 46-52 (2015-07-30) Olive oil phenols are absorbed in humans.Maud N Vissers et al.The Journal of nutrition, 132(3), 409-417 (2002-03-07) [Main pharmacokinetic parameters of p-tyrosol after intravenous injection in rats. Part III: Distribution of p-tyrosol in rat].G A Chernyshova et al.Eksperimental'naia i klinicheskaia farmakologiia, 74(7), 27-29 (2011-09-08) Reversed-phase dispersive liquid-liquid microextraction with multivariate optimization for sensitive HPLC determination of tyrosol and hydroxytyrosol in olive oil.Payman Hashemi et al.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 27(9), 943-947 (2011-09-13) Simultaneous determination of salidroside and its aglycone metabolite p-tyrosol in rat plasma by liquid chromatography-tandem mass spectrometry.Na Guo et al.Molecules (Basel, Switzerland), 17(4), 4733-4754 (2012-04-25)

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