Melting point	-68 ºC
Water Solubility	soluble
Boiling point	231 ºC
Flash point	100 ºC
Density	0.955
Refractive index	1.431-1.433

Symbol(GHS)	Xi
Hazard Codes	R36
SDS/MSDS	S24;S26

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Flavanol Bioavailability in Two Cocoa Products with Different Phenolic Content. A Comparative Study in Humans.Miren Gómez-Juaristi et al.Nutrients, 11(7) (2019-06-30) [Pharmacokinetic and pharmacological studies on cetraxate, an anti-ulcer agent].H Tanaka et al.Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 85(5), 357-366 (1985-05-01) Dual-Surfactant-Capped Ag Nanoparticles as a Highly Selective and Sensitive Colorimetric Sensor for Citrate Detection.Samy M Shaban et al.ACS omega, 5(19), 10696-10703 (2020-05-27) Tissue distribution of naringin and derived metabolites in rats after a single oral administration.Xuan Zeng et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1136, 121846-121846 (2019-12-11) Optimization of ultrasound-accelerated synthesis of enzymatic octyl hydroxyphenylpropionate by response surface methodology.Chih-Chen Lee et al.Biotechnology progress, 26(6), 1629-1634 (2010-10-13) Biotransformation of Cranberry Proanthocyanidins to Probiotic Metabolites by Lactobacillus rhamnosus Enhances Their Anticancer Activity in HepG2 Cells In Vitro.H P Vasantha Rupasinghe et al.Oxidative medicine and cellular longevity, 2019, 4750795-4750795 (2019-07-19) Ion-pairing reversed-phase liquid chromatography fractionation in combination with isotope labeling reversed-phase liquid chromatography-mass spectrometry for comprehensive metabolome profiling.Kevin Guo et al.Journal of chromatography. A, 1218(23), 3689-3694 (2011-05-06) (Z)-3-(4-bromophenyl)-3-(3-pyridyl)allylamine as substrate for studies of myeloperoxidase activity.S Lindvall et al.Chemico-biological interactions, 94(2), 83-99 (1995-02-01) Fate of microbial metabolites of dietary polyphenols in rats: is the brain their target destination?Mattia Gasperotti et al.ACS chemical neuroscience, 6(8), 1341-1352 (2015-04-22) Effects of reduced phenolic acids on metabolism of propionate and palmitate in bovine liver tissue in vitro.J D Cremin et al.Journal of dairy science, 77(12), 3608-3617 (1994-12-01) Impairment of macrophage function in Mongolian gerbils.M Yukawa et al.Veterinary immunology and immunopathology, 33(4), 353-364 (1992-09-01) Portal and hepatic fluxes in sheep and concentrations in cattle ruminal fluid of 3-(4-hydroxyphenyl)propionic, benzoic, 3-phenylpropionic, and trans-cinnamic acids.J D Cremin et al.Journal of animal science, 73(6), 1766-1775 (1995-06-01) A comparison of the sensitivity and specificity of enzyme immunoassays and time-resolved fluoroimmunoassay.I M Roberts et al.Journal of immunological methods, 143(1), 49-56 (1991-09-20) Hydroxycinnamic acids used as external acceptors of electrons: an energetic advantage for strictly heterofermentative lactic acid bacteria.Pasquale Filannino et al.Applied and environmental microbiology, 80(24), 7574-7582 (2014-09-28) Comparative surface energetic study of MatrigelMichael J Hill et al.Colloids and surfaces. B, Biointerfaces, 155, 71-82 (2017-04-16) A metabolite profiling approach to identify biomarkers of flavonoid intake in humans.Wai Mun Loke et al.The Journal of nutrition, 139(12), 2309-2314 (2009-10-09) Profiling Vaccinium macrocarpon components and metabolites in human urine and the urine ex-vivo effect on Candida albicans adhesion and biofilm-formation.Giovanna Baron et al.Biochemical pharmacology, 173, 113726-113726 (2019-11-30) Two cinnamate derivatives produce similar alteration in mRNA expression and activity of antioxidant enzymes in rats.Mi-Kyung Lee et al.Journal of biochemical and molecular toxicology, 17(5), 255-262 (2003-11-05) Decellularized liver matrix as substrates for rescue of acute hepatocytes toxicity.Yung-Te Hou et al.Journal of biomedical materials research. Part B, Applied biomaterials, 108(4), 1592-1602 (2019-10-24) Functionalized Tyrosinase-Lignin Nanoparticles as Sustainable Catalysts for the Oxidation of Phenols.Eliana Capecchi et al.Nanomaterials (Basel, Switzerland), 8(6) (2018-06-20) [Effect of phenylcarboxylic acids on phagocytic activity of neutrophils].K V Zolotarev Klinicheskaia laboratornaia diagnostika, (8)(8), 38-41 (2008-09-24) Phenylpropanoid interconversion in Anigozanthos preissii observed by high-performance liquid chromatography-nuclear magnetic resonance spectroscopy.B Schmitt et al.Phytochemical analysis : PCA, 12(1), 43-47 (2001-11-14) A prophylactic role of a secretory PLA2 of Spodoptera exigua against entomopathogens.Mohammad Vatanparast et al.Developmental and comparative immunology, 95, 108-117 (2019-02-19) Hydra head activator-like immunoreactivity in human brain astrocytomas grade III-IV and the surrounding brain tissue.R Ekman et al.Peptides, 11(2), 271-275 (1990-03-01) Supramolecular Gelatin Networks Based on Inclusion Complexes.Candy Löwenberg et al.Macromolecular bioscience, 20(10), e2000221-e2000221 (2020-08-19) Proanthocyanidin metabolites associated with dietary fibre from in vitro colonic fermentation and proanthocyanidin metabolites in human plasma.Fulgencio Saura-Calixto et al.Molecular nutrition & food research, 54(7), 939-946 (2010-01-21) Production of an anthocyanin-rich food colourant from Thymus moroderi and its application in foods.Miriam Cristina Díaz-García et al.Journal of the science of food and agriculture, 95(6), 1283-1293 (2014-07-22) Mechanistic insight into the activity of tyrosinase from variable-temperature studies in an aqueous/organic solvent.Alessandro Granata et al.Chemistry (Weinheim an der Bergstrasse, Germany), 12(9), 2504-2514 (2005-12-13) In Situ Forming and HYunki Lee et al.ACS applied materials & interfaces, 9(20), 16890-16899 (2017-05-06) Bioavailability of red wine and grape seed proanthocyanidins in rats.Gema Pereira-Caro et al.Food & function, 11(5), 3986-4001 (2020-04-30) Human fecal water inhibits COX-2 in colonic HT-29 cells: role of phenolic compounds.Pernilla C Karlsson et al.The Journal of nutrition, 135(10), 2343-2349 (2005-09-24) Radioimmunoassay of hepatitis B e-antigen (HBeAg): identification of HBeAg not associated with immunoglobulins.A R Neurath et al.The Journal of general virology, 42(3), 493-504 (1979-03-01) Eosinophils are a major source of nitric oxide-derived oxidants in severe asthma: characterization of pathways available to eosinophils for generating reactive nitrogen species.J C MacPherson et al.Journal of immunology (Baltimore, Md. : 1950), 166(9), 5763-5772 (2001-04-21) Enhanced tissue adhesiveness of injectable gelatin hydrogels through dual catalytic activity of horseradish peroxidase.Hoang T T T, et al. Biopolymers, 109(1), e23077-e23077 (2018) Tailorable cell culture platforms from enzymatically cross-linked multifunctional poly (ethylene glycol)-based hydrogels.Menzies D J, et al. Biomacromolecules, 14(2), 413-423 (2013) 3-hydroxy-3-phenylpropanoic acid is an intermediate in the biosynthesis of benzoic acid and salicylic acid but benzaldehyde is not.A P Jarvis et al.Planta, 212(1), 119-126 (2001-02-24) Dose-Dependent Increase in Unconjugated Cinnamic Acid Concentration in Plasma Following Acute Consumption of Polyphenol Rich Curry in the Polyspice Study.Sumanto Haldar et al.Nutrients, 10(7) (2018-07-25) Inhibitory Effects of Quercetin and Its Human and Microbial Metabolites on Xanthine Oxidase Enzyme.Violetta Mohos et al.International journal of molecular sciences, 20(11) (2019-06-05) Green and efficient production of octyl hydroxyphenylpropionate using an ultrasound-assisted packed-bed bioreactor.Chih Chen Lee et al.Journal of industrial microbiology & biotechnology, 39(4), 655-660 (2011-11-29) Testing the Pharmacokinetic Interactions of 24 Colonic Flavonoid Metabolites with Human Serum Albumin and Cytochrome P450 Enzymes.Violetta Mohos et al.Biomolecules, 10(3) (2020-03-12) Solute Partitioning in Micelles: Combining Molecular Dynamics Simulations, COSMOmic, and Experiments.D Yordanova et al.The journal of physical chemistry. B, 121(23), 5794-5809 (2017-05-24) Microbial metabolites of proanthocyanidins reduce chemical carcinogen-induced DNA damage in human lung epithelial and fetal hepatic cells in vitro.W P D Wass Thilakarathna et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 125, 479-493 (2019-02-09) Optimization of an in vitro gut microbiome biotransformation platform with chlorogenic acid as model compound: From fecal sample to biotransformation product identification.Olivier Mortelé et al.Journal of pharmaceutical and biomedical analysis, 175, 112768-112768 (2019-08-10) An enzyme-linked immunosorbent assay (ELISA) for human semen identification based on a biotinylated monoclonal antibody to a seminal vesicle-specific antigen.J C Herr et al.Journal of forensic sciences, 32(2), 346-356 (1987-03-01) Antimicrobial activity of catechol functionalized-chitosan versus Staphylococcus epidermidis.Andrea Amato et al.Carbohydrate polymers, 179, 273-281 (2017-11-08) Carbon nanotubes supported tyrosinase in the synthesis of lipophilic hydroxytyrosol and dihydrocaffeoyl catechols with antiviral activity against DNA and RNA viruses.Giorgia Botta et al.Bioorganic & medicinal chemistry, 23(17), 5345-5351 (2015-08-12) Fabrication of photo-crosslinkable glycol chitosan hydrogel as a tissue adhesive.Min Lu et al.Carbohydrate polymers, 181, 668-674 (2017-12-20) 3-p-hydroxyphenylpropionic acid--a sensitive fluorogenic substrate for automated fluorometric enzyme immunoassays.T Tuuminen et al.Journal of immunoassay, 12(1), 29-46 (1991-01-01) Beta-Glucan and Phenolic Compounds: Their Concentration and Behavior during in Vitro Gastrointestinal Digestion and Colonic Fermentation of Different Barley-Based Food Products.Juana I Mosele et al.Journal of agricultural and food chemistry, 66(34), 8966-8975 (2018-08-07) Stability and anti-topoisomerase activity of phenolic compounds of Capsicum annuum "Serrano" after gastrointestinal digestion and in vitro colonic fermentation.Alicia P Cárdenas-Castro et al.International journal of food sciences and nutrition, 71(7), 826-838 (2020-03-07) Further studies on the metabolism of carbidopa, (minus)-L-alpha-hydrazino-3,4-dihydroxy-alpha-methylbenzenepropanoic acid monohydrate, in the human, Rhesus monkey, dog, and rat.S Vickers et al.Journal of medicinal chemistry, 18(2), 134-138 (1975-02-01) Exploring recombinant flavonoid biosynthesis in metabolically engineered Escherichia coli.Kevin T Watts et al.Chembiochem : a European journal of chemical biology, 5(4), 500-507 (2004-06-09) A simple neridronate-based surface coating strategy for upconversion nanoparticles: highly colloidally stableUliana Kostiv et al.Nanoscale, 9(43), 16680-16688 (2017-10-27) Use of 3-(4-hydroxyphenyl)propionic acid as electron donating compound in a potentiometric aflatoxin M1-immunosensor.Steffen Rameil et al.Analytica chimica acta, 661(1), 122-127 (2010-02-02) Pharmacokinetics and Metabolism of Naringin and Active Metabolite Naringenin in Rats, Dogs, Humans, and the Differences Between Species.Yang Bai et al.Frontiers in pharmacology, 11, 364-364 (2020-04-16) Modification and crosslinking of gelatin-based biomaterials as tissue adhesives.Yi Liu et al.Colloids and surfaces. B, Biointerfaces, 174, 316-323 (2018-11-26) Flavanol plasma bioavailability is affected by metabolic syndrome in rats.Maria Margalef et al.Food chemistry, 231, 287-294 (2017-04-30) Poly(2-ethyl-2-oxazoline) conjugates with doxorubicin for cancer therapy: In vitro and in vivo evaluation and direct comparison to poly[N-(2-hydroxypropyl)methacrylamide] analogues.Ondrej Sedlacek et al.Biomaterials, 146, 1-12 (2017-09-12) Synthetic peptide-based enzyme-linked immunosorbent assay for serodiagnosis of visceral leishmaniasis.C Fargeas et al.Journal of clinical microbiology, 34(2), 241-248 (1996-02-01) Supplementation with grape seed polyphenols results in increased urinary excretion of 3-hydroxyphenylpropionic Acid, an important metabolite of proanthocyanidins in humans.Natalie C Ward et al.Journal of agricultural and food chemistry, 52(17), 5545-5549 (2004-08-19) Hypocholesterolemic and antioxidative effects of naringenin and its two metabolites in high-cholesterol fed rats.Seon-Min Jeon et al.Translational research : the journal of laboratory and clinical medicine, 149(1), 15-21 (2007-01-02) Molecularly imprinted polymer using-p-hydroxybenzoic acid, p-hydroxyphenylacetic acid and p-hydroxyphenylpropionic acid as templates.B W Sun et al.Journal of molecular recognition : JMR, 14(6), 388-392 (2002-01-05) Growth-rate dependency of de novo resveratrol production in chemostat cultures of an engineered Saccharomyces cerevisiae strain.Tim Vos et al.Microbial cell factories, 14, 133-133 (2015-09-16) Biocatalytic acylation of sugar alcohols by 3-(4-hydroxyphenyl) propionic acid.Croitoru R, et al. Process Biochemistry (Oxford, United Kingdom), 47(12), 1894-1902 (2012) The microbiota regulate neuronal function and fear extinction learning.Coco Chu et al.Nature, 574(7779), 543-548 (2019-10-28) Development of a targeted method for twenty-three metabolites related to polyphenol gut microbial metabolism in biological samples, using SPE and UHPLC-ESI-MS/MS.Mattia Gasperotti et al.Talanta, 128, 221-230 (2014-07-26) Efficient syntheses of bolaform surfactants from L-rhamnose and/or 3-(4-hydroxyphenyl) propionic acid.Akong F O and Bouquillon S Green Chemistry, 17(6), 3290-3300 (2015) An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds.Yunbao Liu et al.Journal of natural products, 73(7), 1193-1195 (2010-06-23) Effects of glycine and bovine serum albumin on inhibition of propionate metabolism in ovine hepatocytes caused by reduced phenolic monomers.J D Cremin et al.Journal of animal science, 73(10), 3009-3021 (1995-10-01) Kinetic cooperativity of tyrosinase. A general mechanism.Jose Luis Muñoz-Muñoz et al.Acta biochimica Polonica, 58(3), 303-311 (2011-09-03) Quality assurance in immunoassay performance--comparison of different enzyme immunoassays for the determination of caffeine in consumer products.Julia Grandke et al.Analytical and bioanalytical chemistry, 405(5), 1601-1611 (2012-12-12)

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