Melting point	12 ºC
Water Solubility	Insoluble
Boiling point	237-239 ºC
Flash point	101 ºC
Density	0.831
Refractive index	1.433-1.44

Symbol(GHS)	Xi;N
Hazard Codes	R38;R51/53
SDS/MSDS	S29;S37;S61

Source	SDS/MSDS Samples
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Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Ornidazole-induced liver damage: report of three cases and review of the literature.Fehmi Tabak et al.Liver international : official journal of the International Association for the Study of the Liver, 23(5), 351-354 (2004-01-08) [Application of ornigil in the perioperative prevention and therapy of infectious complications after abdominal surgery].M E Nichitaĭlo et al.Klinichna khirurhiia, (4)(4), 65-67 (2012-06-28) The evaluation of genotoxic potential of ornidazole, nitroimidazole, in lymphocyte culture of patients with amebiasis.Mevlit Ikbal et al.Drug and chemical toxicology, 34(2), 162-166 (2011-02-15) Molecularly imprinted solid phase extraction method for simultaneous determination of seven nitroimidazoles from honey by HPLC-MS/MS.Xiu-Chun Guo et al.Talanta, 166, 101-108 (2017-02-19) Design of sterculia gum based double potential antidiarrheal drug delivery system.Baljit Singh et al.Colloids and surfaces. B, Biointerfaces, 82(2), 325-332 (2010-10-05) Efficient preparation of nitrogen-doped fluorescent carbon dots for highly sensitive detection of metronidazole and live cell imaging.Guodong Ren et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 234, 118251-118251 (2020-03-21) Intra-Abdominal Nocardiosis-Case Report and Review of the Literature.Lucas Tramèr et al.Journal of clinical medicine, 9(7) (2020-07-11) A dispersive liquid-liquid micellar microextraction for the determination of pharmaceutical compounds in wastewaters using ultra-high-performace liquid chromatography with DAD detection.Sarah Montesdeoca-Esponda et al.Biomedical chromatography : BMC, 29(3), 353-356 (2014-07-25) Facile synthesis of conjugated microporous polymer with spherical structure for solid phase extraction of phenyl urea herbicides.Yaxing Guo et al.Journal of chromatography. A, 1622, 461131-461131 (2020-05-10) Evaluation of efficacy and tolerability of fixed dose combination of ofloxacin with ornidazole infusion (infusion O2) in the management of diarrhoea and dysentery.Arif A Faruqui et al.Journal of the Indian Medical Association, 110(3), 193-196 (2012-10-04) Analytical investigation of the influence of ornidazole on the native protein fluorescence.Hazim M Ali et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 201, 178-184 (2018-05-12) Acute pancreatitis following doxycycline and ornidazole coadministration.Serkan Ocal et al.JOP : Journal of the pancreas, 11(6), 614-616 (2010-11-12) Comparison of the Utility of RP-TLC Technique and Different Computational Methods to Assess the Lipophilicity of Selected Antiparasitic, Antihypertensive, and Anti-inflammatory Drugs.Alina Pyka-Pająk et al.Molecules (Basel, Switzerland), 24(17) (2019-09-05) Plumbagin suppresses chronic periodontitis in rats via down-regulation of TNF-α, IL-1β and IL-6 expression.Xin-Yi Zheng et al.Acta pharmacologica Sinica, 38(8), 1150-1160 (2017-05-30) Development of a monoclonal antibody-based indirect competitive enzyme-linked immunosorbent assay for nitroimidazoles in edible animal tissues and feeds.Wei Han et al.Journal of pharmaceutical and biomedical analysis, 120, 84-91 (2015-12-31) The role of C-type natriuretic peptide in rat testes during spermatogenesis.Dong-Hui Huang et al.Asian journal of andrology, 13(2), 275-280 (2010-12-21) Simultaneous quantification of metronidazole, tinidazole, ornidazole and morinidazole in human saliva.Yongqing Wang et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 899, 27-30 (2012-06-05) Determination of brusatol in plasma and tissues by LC-MS method and its application to a pharmacokinetic and distribution study in mice.Nan Guo et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1053, 20-26 (2017-04-14) Extractional spectrophotometric analysis of metronidazole, tinidazole, ornidazole and secnidazole bases through acid-dye complexation using bromothymol blue dye.Khaled M Darwish et al.Pakistan journal of pharmaceutical sciences, 25(1), 207-217 (2011-12-22) Binding preference of nitroimidazolic radiosensitizers to nucleobases and nucleosides probed by electrospray ionization mass spectrometry and density functional theory.S Pandeti et al.The Journal of chemical physics, 150(1), 014302-014302 (2019-01-10) Investigation of chiral inversion and pharmacokinetics of laevo-ornidazole by high-performance liquid chromatography.L-L Mu et al.Journal of clinical pharmacy and therapeutics, 38(1), 31-35 (2012-11-22) In Vitro Anaerobic Pharmacokinetic/Pharmacodynamic Model to Simulate the Bactericidal Activity of Levornidazole Against Bacteroides fragilis.Jiali Hu et al.Clinical therapeutics, 39(4), 828-836 (2017-04-02) Comment on "Simultaneous quantification of metronidazole, tinidazole, ornidazole and morinidazole in human saliva": Saliva or gingival crevicular fluid?Yi Jiang et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 913-914, 169-170 (2013-01-15) A high-throughput UHPLC method for the analysis of 5-nitroimidazole residues in milk based on salting-out assisted liquid-liquid extraction.Maykel Hernández-Mesa et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1068-1069, 125-130 (2017-10-24) Efficacy and safety of morinidazole in pelvic inflammatory disease: results of a multicenter, double-blind, randomized trial.C Cao et al.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 36(7), 1225-1230 (2017-03-08) [Ornidazole (Tiberal) in periodontal therapy].U P Saxer et al.Schweizerische Monatsschrift fur Zahnheilkunde = Revue mensuelle suisse d'odonto-stomatologie, 93(10), 991-1001 (1983-10-01) Microbiological outcomes of systemic ornidazole use in chronic periodontitis. Part II.A R Pradeep et al.Journal of the International Academy of Periodontology, 14(2), 50-54 (2012-07-18) Autotransplantation of mature and immature third molars in 23 Chinese patients: a clinical and radiological follow-up study.Haozhe Tang et al.BMC oral health, 17(1), 163-163 (2017-12-30) Severe hepatotoxicity as a result of extended use of ornidazole.Yusuf Coskun et al.Journal of clinical gastroenterology, 46(6), 529-530 (2012-06-14) Synthesis and characterization of pH-sensitive hydrogel composed of carboxymethyl chitosan for colon targeted delivery of ornidazole.Subhash S Vaghani et al.Carbohydrate research, 347(1), 76-82 (2011-11-22) Genetically different clonal isolates of Trichomonas gallinae, obtained from the same bird, can vary in their drug susceptibility, an in vitro evidence.Elvira Zimre-Grabensteiner et al.Parasitology international, 60(2), 213-215 (2011-02-25) Effects of systemic ornidazole, systemic and local compound ornidazole and pefloxacin mesylate on experimental periodontitis in rats.Rui Liu et al.Medical science monitor : international medical journal of experimental and clinical research, 18(3), BR95-B102 (2012-03-01) Enzyme sensitive smart inulin-dehydropeptide conjugate self-assembles into nanostructures useful for targeted delivery of ornidazole.Kriti Shivhare et al.International journal of biological macromolecules, 106, 775-783 (2017-08-19) Development and validation of a QuEChERS method for the analysis of 5-nitroimidazole traces in infant milk-based samples by ultra-high performance liquid chromatography-tandem mass spectrometry.Maykel Hernández-Mesa et al.Journal of chromatography. A, 1562, 36-46 (2018-06-05) [Multicenter randomized controlled clinical study on levornidazole and sodium chloride injection in the treatment of pelvic anaerobic infections].Ling Ma et al.Zhonghua fu chan ke za zhi, 45(10), 754-756 (2010-12-24) Biomarkers of genotoxicity and genomic instability in a non-human primate, Cebus libidinosus (Cebidae, Platyrrhini), exposed to nitroimidazole derivatives.Marta Dolores Mudry et al.Mutation research, 721(1), 108-113 (2011-01-25) Determination of nitroimidazole residues in aquaculture tissue using ultra high performance liquid chromatography coupled to tandem mass spectrometry.Anna Gadaj et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 960, 105-115 (2014-05-06) Solid-state studies of the triclinic (Z' = 2) antiprotozoal drug ternidazole.Nathalie Mahé et al.Journal of pharmaceutical sciences, 100(6), 2258-2266 (2011-01-20) Phenotypic and transcriptional profiling in Entamoeba histolytica reveal costs to fitness and adaptive responses associated with metronidazole resistance.Gil M Penuliar et al.Frontiers in microbiology, 6, 354-354 (2015-05-23) Multiple fixed drug eruption caused by ornidazole.Sanjeev Gupta et al.Dermatitis : contact, atopic, occupational, drug, 21(6), 330-333 (2010-12-15) Preparation and properties of visible light responsive Y3+ doped Bi5Nb3O15 photocatalysts for Ornidazole decomposition.Jie Zhao et al.Journal of hazardous materials, 229-230, 151-158 (2012-06-22) [Determination of nitroimidazoles in oral hygiene by ultra-performance liquid chromatography-tandem mass spectrometry].Juan Xu et al.Se pu = Chinese journal of chromatography, 29(5), 450-453 (2011-08-19) Ornidazole-induced autoimmune hepatitis.Galip Ersöz et al.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 22(5), 494-499 (2012-01-12) Fabrication of magnetic porous organic framework for effective enrichment and assay of nitroimidazoles in chicken meat.Qianqian Wang et al.Food chemistry, 332, 127427-127427 (2020-07-04) Interventions for maintenance of surgically induced remission in Crohn's disease: a network meta-analysis.Zipporah Iheozor-Ejiofor et al.The Cochrane database of systematic reviews, 9, CD013210-CD013210 (2019-09-13) In vitro simulation of in vivo pharmacokinetic model with intravenous administration via flow rate modulation.Yuan-Cheng Chen et al.Journal of pharmacokinetics and pharmacodynamics, 42(1), 33-43 (2014-10-31) Screening for potent and selective anticlostridial leads among FDA-approved drugs.Ahmed AbdelKhalek et al.The Journal of antibiotics, 73(6), 392-409 (2020-03-07) Comparative studies of immobilized chiral stationary phases based on polysaccharide derivatives for enantiomeric separation of 15 azole compounds.Bolin Zhu et al.Electrophoresis, 39(16), 2107-2116 (2018-05-19) Determination of nitroimidazole residues in aquaculture tissue using ultra high performance liquid chromatography coupled to tandem mass spectrometryGadaj A, et al. Journal of Chromatography. B, Biomedical Applications, 960, 105-115 (2014) Systemic ornidazole as an adjunct to non-surgical periodontal therapy in the treatment of chronic periodontitis: a randomized, double-masked, placebo-controlled clinical trial.A R Pradeep et al.Journal of periodontology, 83(9), 1149-1154 (2012-01-10) A colorimetric method for the evaluation of anti-giardial drugs in vitro.Kruawan Hounkong et al.Experimental parasitology, 127(2), 600-603 (2010-09-30) Endodontic treatment of necrosed primary teeth using two different combinations of antibacterial drugs: an in vivo study.C Pinky et al.Journal of the Indian Society of Pedodontics and Preventive Dentistry, 29(2), 121-127 (2011-09-14)

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