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Symbol(GHS)	Xn
Hazard Codes	R21
SDS/MSDS	S36/37

Source	SDS/MSDS Samples
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Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Involvement of Mcl1 in diallyl disulfide-induced G2/M cell cycle arrest in HL-60 cells.Lan Yi et al.Oncology reports, 27(6), 1911-1917 (2012-03-02) Diallyl disulfide impairs hippocampal neurogenesis in the young adult brain.Seung Taek Ji et al.Toxicology letters, 221(1), 31-38 (2013-06-05) Development, characterization and efficacy of niosomal diallyl disulfide in treatment of disseminated murine candidiasis.Maroof Alam et al.Nanomedicine : nanotechnology, biology, and medicine, 9(2), 247-256 (2012-08-04) Coumarin polysulfides inhibit cell growth and induce apoptosis in HCT116 colon cancer cells.Nathaniel Edward Bennett Saidu et al.Bioorganic & medicinal chemistry, 20(4), 1584-1593 (2012-01-24) The chemopreventive effects of aged garlic extract against cadmium-induced toxicity.Akeem O Lawal et al.Environmental toxicology and pharmacology, 32(2), 266-274 (2011-08-17) Garlic extract diallyl sulfide (DAS) activates nuclear receptor CAR to induce the Sult1e1 gene in mouse liver.Tatsuya Sueyoshi et al.PloS one, 6(6), e21229-e21229 (2011-06-24) The role of diallyl sulfides and dipropyl sulfides in the in vitro antimicrobial activity of the essential oil of garlic, Allium sativum L., and leek, Allium porrum L.Sergio Casella et al.Phytotherapy research : PTR, 27(3), 380-383 (2012-05-23) Resveratrol and diallyl disulfide enhance curcumin-induced sarcoma cell apoptosis.Laura Masuelli et al.Frontiers in bioscience (Landmark edition), 17, 498-508 (2011-12-29) Inhibition of matrix metalloproteinase activities and tightening of tight junctions by diallyl disulfide in AGS human gastric carcinoma cells.Hyun Soo Park et al.Journal of food science, 76(4), T105-T111 (2012-03-16) Impact of the uremic milieu on the osteogenic potential of mesenchymal stem cells.Diana Lanza et al.PloS one, 10(1), e0116468-e0116468 (2015-01-31) Diallyl sulfide, diallyl disulfide, and diallyl trisulfide inhibit migration and invasion in human colon cancer colo 205 cells through the inhibition of matrix metalloproteinase-2, -7, and -9 expressions.Kuang-Chi Lai et al.Environmental toxicology, 28(9), 479-488 (2011-06-23) Nutraceutic Potential of Two Allium Species and Their Distinctive Organosulfur Compounds: A Multi-Assay Evaluation.Zahira Fernández-Bedmar et al.Foods (Basel, Switzerland), 8(6) (2019-06-27) Diallyl disulfide suppresses proliferation and induces apoptosis in human gastric cancer through Wnt-1 signaling pathway by up-regulation of miR-200b and miR-22.Hailin Tang et al.Cancer letters, 340(1), 72-81 (2013-07-16) Effect of diallyl disulfide on insulin-like growth factor signaling molecules involved in cell survival and proliferation of human prostate cancer cells in vitro and in silico approach through docking analysis.R Arunkumar et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 19(10), 912-923 (2012-06-29) Effect of processing conditions on the organosulfides of shallot (Allium cepa L. Aggregatum group).Restituto Tocmo et al.Journal of agricultural and food chemistry, 62(23), 5296-5304 (2014-05-21) Effects of onion (Allium cepa L.) and garlic (Allium sativum L.) essential oils on the Aspergillus versicolor growth and sterigmatocystin production.Sunčica Kocić-Tanackov et al.Journal of food science, 77(5), M278-M284 (2012-04-14) Inhibitory effects of diallyl disulfide on the production of inflammatory mediators and cytokines in lipopolysaccharide-activated BV2 microglia.Hye Young Park et al.Toxicology and applied pharmacology, 262(2), 177-184 (2012-05-09) DADS downregulates the Rac1-ROCK1/PAK1-LIMK1-ADF/cofilin signaling pathway, inhibiting cell migration and invasion.Yujuan Zhou et al.Oncology reports, 29(2), 605-612 (2012-12-13) Diallyl disulphide and lovastatin: effects on energy and protein utilisation in, as well as methane emission from, sheep.Fenja Klevenhusena et al.Archives of animal nutrition, 65(4), 255-266 (2011-09-06) Optimizations of packed sorbent and inlet temperature for large volume-direct aqueous injection-gas chromatography to determine high boiling volatile organic compounds in water.Bofan Yu et al.Journal of chromatography. A, 1356, 221-229 (2014-07-07) Diallyl sulfide, diallyl disulfide and diallyl trisulfide affect drug resistant gene expression in colo 205 human colon cancer cells in vitro and in vivo.Kuang-Chi Lai et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 19(7), 625-630 (2012-03-09) Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.Pier Giovanni Baraldi et al.Journal of medicinal chemistry, 53(14), 5085-5107 (2010-04-02) Effect of garlic-derived organosulfur compounds on mitochondrial function and integrity in isolated mouse liver mitochondria.Andres A Caro et al.Toxicology letters, 214(2), 166-174 (2012-09-11) Effect of allyl sulfides from garlic essential oil on intracellular ca2+ levels in renal tubular cells.Chung-Ren Jan et al.Journal of natural products, 75(12), 2101-2107 (2012-11-21) Garlicin attenuates reperfusion no-reflow in a catheter-based porcine model of acute myocardial infarction.Yang Peng et al.Artificial cells, blood substitutes, and immobilization biotechnology, 40(4), 285-289 (2012-04-05) Hydrogen sulfide protects from colitis and restores intestinal microbiota biofilm and mucus production.Jean-Paul Motta et al.Inflammatory bowel diseases, 21(5), 1006-1017 (2015-03-05) Essential oil composition and antiradical activity of the oil of Iraq plants.Mustafa Kiralan et al.Natural product research, 26(2), 132-139 (2011-08-11) [Mechanism of Fas/FasL signal transduction pathway in K562 cell apoptosis induced by diallyl disulfide].Xiao-Cheng Yin et al.Zhongguo shi yan xue ye xue za zhi, 19(3), 634-637 (2011-07-07) The defense substance allicin from garlic permeabilizes membranes of Beta vulgaris, Rhoeo discolor, Chara corallina and artificial lipid bilayers.Martin C H Gruhlke et al.Biochimica et biophysica acta, 1850(4), 602-611 (2014-12-09) Diallyl disulphide, a beneficial component of garlic oil, causes a redistribution of cell-cycle growth phases, induces apoptosis, and enhances butyrate-induced apoptosis in colorectal adenocarcinoma cells (HT-29).Mohammed O Altonsy et al.Nutrition and cancer, 63(7), 1104-1113 (2011-09-16) Garlic-derived diallyl disulfide modulates peroxisome proliferator activated receptor gamma co-activator 1 alpha in neuroblastoma cells.Beatrice Pagliei et al.Biochemical pharmacology, 85(3), 335-344 (2012-11-28) Preparation of solid lipid nanoparticles loaded with garlic oil and evaluation of their in vitro and in vivo characteristics.Z Wencui et al.European review for medical and pharmacological sciences, 19(19), 3742-3750 (2015-10-28) Diallyl disulfide induces Ca2+ mobilization in human colon cancer cell line SW480.Chung-Yi Chen et al.Archives of toxicology, 86(2), 231-238 (2011-09-01) The attenuation of early benzo(a)pyrene-induced carcinogenic insults by diallyl disulfide (DADS) in MCF-10A cells.Yasmeen M Nkrumah-Elie et al.Nutrition and cancer, 64(7), 1112-1121 (2012-09-26) Garlic (Allium sativum) stimulates lipopolysaccharide-induced tumor necrosis factor-alpha production from J774A.1 murine macrophages.Jessica Sung et al.Phytotherapy research : PTR, 29(2), 288-294 (2014-11-05) Studies on purification of allicin by molecular distillation.Guo Liang et al.Journal of the science of food and agriculture, 92(7), 1475-1478 (2012-01-10) Development of a method to determine essential oil residues in cow milk.A Hallier et al.Journal of dairy science, 96(3), 1447-1454 (2013-01-15) Diallyl disulfide reduced dose-dependently the number of lymphocyte subsets and monocytes in rats.Yoko Hashizume et al.Journal of nutritional science and vitaminology, 58(4), 292-296 (2012-11-08) Diallyl disulfide-induced apoptosis in a breast-cancer cell line (MCF-7) may be caused by inhibition of histone deacetylation.Mohammed O Altonsy et al.Nutrition and cancer, 64(8), 1251-1260 (2012-11-21) The activation of HO-1/Nrf-2 contributes to the protective effects of diallyl disulfide (DADS) against ethanol-induced oxidative stress.Tao Zeng et al.Biochimica et biophysica acta, 1830(10), 4848-4859 (2013-07-03)

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