Melting point	130-135 ºC
Water Solubility	1-5 g/100 mL at 21 ºC

Symbol(GHS)	T
Hazard Codes	R25
SDS/MSDS	S36/37/39;S45

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Synthesis and functionalization of 3-alkylidene-1,2-diazetidines using transition metal catalysis.Michael J Brown et al.Organic letters, 13(7), 1686-1689 (2011-03-04) Experimental and computational studies of the structure and vibrational spectra of azetidine derivatives.Thompson CA, et al. Journal of Molecular Structure, 491(1), 67-80 (1999) Synthesis of new functionalized aziridine-2- and azetidine-3-carboxylic acid derivatives of potential interest for biological and foldameric applications.Asta Žukauskaitė et al.Amino acids, 41(3), 541-558 (2011-03-23) A theoretical rationale for why azetidine has a faster rate of formation than oxetane in TC(6-4) photoproducts.Zhao bo Yang et al.The journal of physical chemistry. B, 115(31), 9681-9686 (2011-06-21) Chemistry and pharmacology of nicotinic ligands based on 6-[5-(azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol (AMOP-H-OH) for possible use in depression.Alan P Kozikowski et al.ChemMedChem, 4(8), 1279-1291 (2009-07-02) Link atom bond length effect in ONIOM excited state calculations.Marco Caricato et al.The Journal of chemical physics, 133(5), 054104-054104 (2010-08-17) Asymmetric synthesis of α,β-diamino acid derivatives with an aziridine-, azetidine- and γ-lactone-skeleton via Mannich-type additions across α-chloro-N-sulfinylimines.Gert Callebaut et al.Organic & biomolecular chemistry, 10(11), 2326-2338 (2012-02-09) Structure based design of novel irreversible FAAH inhibitors.Jane L Wang et al.Bioorganic & medicinal chemistry letters, 19(20), 5970-5974 (2009-09-22) Mini-Reviews in Organic Chemistry, 1, 133-148 (2004) Phototransformations of azetidine radical cations stabilized in freonic matrices.Sorokin ID, et al. High Energy Chemistry, 48(3), 180-184 (2014) Synthesis, 243-243 (2007) Fatty acid amide hydrolase inhibitors. 3: tetra-substituted azetidine ureas with in vivo activity.Stephen D Roughley et al.Bioorganic & medicinal chemistry letters, 22(2), 901-906 (2012-01-03) Synthesis and profiling of a diverse collection of azetidine-based scaffolds for the development of CNS-focused lead-like libraries.Jason T Lowe et al.The Journal of organic chemistry, 77(17), 7187-7211 (2012-08-03) Synthesis, 3245-3245 (2006) Azetidine derivatives as novel gamma-aminobutyric acid uptake inhibitors: synthesis, biological evaluation, and structure-activity relationship.Mark R Faust et al.European journal of medicinal chemistry, 45(6), 2453-2466 (2010-03-12) Synthesis of 3-methoxyazetidines via an aziridine to azetidine rearrangement and theoretical rationalization of the reaction mechanism.Sonja Stanković et al.The Journal of organic chemistry, 76(7), 2157-2167 (2011-03-11) Azetidine-based inhibitors of dipeptidyl peptidase IV (DPP IV).Dana Ferraris et al.Current topics in medicinal chemistry, 7(6), 597-608 (2007-03-14) Synthesis from D-altrose of (5R,6R,7R,8S)-5,7-dihydroxy-8-hydroxymethylconidine and 2,4-dideoxy-2,4-imino-D-glucitol, azetidine analogues of swainsonine and 1,4-dideoxy-1,4-imino-D-mannitol.Noelia Araújo et al.Organic letters, 14(16), 4174-4177 (2012-07-31) Fatty acid amide hydrolase inhibitors. Surprising selectivity of chiral azetidine ureas.Terance Hart et al.Bioorganic & medicinal chemistry letters, 19(15), 4241-4244 (2009-06-12) Silver(I)-catalyzed dual activation of propargylic alcohol and aziridine/azetidine: triggering ring-opening and endo-selective ring-closing in a cascade.Milan Bera et al.The Journal of organic chemistry, 74(22), 8814-8817 (2009-10-17) GC-MS, GC-MS/MS and GC-IR differentiation of desoxy cathinone derivatives: Cyclic tertiary amines related to MDPV.Younis Abiedalla et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1048, 38-48 (2017-02-16) Complex N-heterocycle synthesis via iron-catalyzed, direct C-H bond amination.Elisabeth T Hennessy et al.Science (New York, N.Y.), 340(6132), 591-595 (2013-05-04) Inhibition of nonmammalian glycosidases by azetidine iminosugars derived from stable 3,5-di-O-triflates of pentoses.Gabriel M J Lenagh-Snow et al.Organic letters, 13(21), 5834-5837 (2011-10-12) Polyazetidine-coated microelectrodes: electrochemical and diffusion characterization of different redox substrates.Massimo Di Fusco et al.The journal of physical chemistry. B, 115(5), 972-979 (2011-01-05) Synthesis, biochemical and molecular modelling studies of antiproliferative azetidinones causing microtubule disruption and mitotic catastrophe.Niamh M O'Boyle et al.European journal of medicinal chemistry, 46(9), 4595-4607 (2011-08-16) A theoretical study of dihydrogen bonds in small protonated rings: aziridine and azetidine cations.B G Oliveira et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 75(2), 563-566 (2009-12-05) Identification of spirocyclic piperidine-azetidine inverse agonists of the ghrelin receptor.Daniel W Kung et al.Bioorganic & medicinal chemistry letters, 22(13), 4281-4287 (2012-06-09) Exploration of novel 3-substituted azetidine derivatives as triple reuptake inhibitors.Younghue Han et al.Journal of medicinal chemistry, 55(18), 8188-8192 (2012-09-04) In vivo and in vitro SAR of tetracyclic MAPKAP-K2 (MK2) inhibitors. Part II.Laszlo Revesz et al.Bioorganic & medicinal chemistry letters, 20(15), 4719-4723 (2010-07-02) Functional selective ATP receptor signaling controlled by the free fatty acid receptor 2 through a novel allosteric modulation mechanism.Simon Lind et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(6), 6887-6903 (2019-02-28) Development of novel M1 antagonist scaffolds through the continued optimization of the MLPCN probe ML012.Bruce J Melancon et al.Bioorganic & medicinal chemistry letters, 22(15), 5035-5040 (2012-07-04) Discovery of azetidinyl ketolides for the treatment of susceptible and multidrug resistant community-acquired respiratory tract infections.Thomas V Magee et al.Journal of medicinal chemistry, 52(23), 7446-7457 (2009-09-25) A practical method for targeted library design balancing lead-like properties with diversity.Michael J Stocks et al.ChemMedChem, 4(5), 800-808 (2009-04-11)

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