Melting point	30-32 ºC
Water Solubility	1.8 g/L (20 ºC)
Boiling point	193-196 ºC
Flash point	81 ºC
Density	0.86

Symbol(GHS)	Xi
Hazard Codes	R36
SDS/MSDS	S26;S39

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Reduction of pantethine in rabbit ocular lens homogenate.D H Fisher et al.Journal of pharmaceutical and biomedical analysis, 15(5), 653-662 (1997-02-01) An Arabidopsis mutant impaired in coenzyme A biosynthesis is sugar dependent for seedling establishment.Silvia Rubio et al.Plant physiology, 140(3), 830-843 (2006-01-18) Pantethine treatment is effective in recovering the disease phenotype induced by ketogenic diet in a pantothenate kinase-associated neurodegeneration mouse model.Dario Brunetti et al.Brain : a journal of neurology, 137(Pt 1), 57-68 (2013-12-10) Delay or inhibition of rat lens opacification using pantethine and WR-77913.J I Clark et al.Experimental eye research, 62(1), 75-84 (1996-01-01) Self-assembly of protein aggregates in ageing disorders: the lens and cataract model.John I Clark Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 368(1617), 20120104-20120104 (2013-03-27) Enhancement of L-3-hydroxybutyryl-CoA dehydrogenase activity and circulating ketone body levels by pantethine. Relevance to dopaminergic injury.Emilie Cornille et al.BMC neuroscience, 11, 51-51 (2010-04-27) Pantethine inhibits the formation of high-Tc protein aggregates in gamma B crystallin solutions.G Friberg et al.Current eye research, 15(12), 1182-1190 (1996-12-01) Protection against cerebral malaria by the low-molecular-weight thiol pantethine.Marie-France Penet et al.Proceedings of the National Academy of Sciences of the United States of America, 105(4), 1321-1326 (2008-01-16) Pantethine rescues phosphopantothenoylcysteine synthetase and phosphopantothenoylcysteine decarboxylase deficiency in Escherichia coli but not in Pseudomonas aeruginosa.Carl J Balibar et al.Journal of bacteriology, 193(13), 3304-3312 (2011-05-10) The STM4195 gene product (PanS) transports coenzyme A precursors in Salmonella enterica.Dustin C Ernst et al.Journal of bacteriology, 197(8), 1368-1377 (2015-02-04) Pantethine. Alternative medicine review : a journal of clinical therapeutic, 3(5), 379-381 (1998-11-05) Modulation of the chaperone-like activity of bovine alpha-crystallin.J I Clark et al.Proceedings of the National Academy of Sciences of the United States of America, 93(26), 15185-15189 (1996-12-24) Dietary and nutraceutical options for managing the hypertriglyceridemic patient.Joel J Pins et al.Progress in cardiovascular nursing, 21(2), 89-93 (2006-06-09) Variation in pantothenate kinase type determines the pantothenamide mode of action and impacts on coenzyme A salvage biosynthesis.Marianne de Villiers et al.The FEBS journal, 281(20), 4731-4753 (2014-08-27) The synthesis of minds and molecules leads to potential therapy for pantothenate kinase-associated neurodegeneration.Andrea H Németh Brain : a journal of neurology, 137(Pt 1), 8-11 (2014-01-16) Can drugs or micronutrients prevent cataract?J J Harding Drugs & aging, 18(7), 473-486 (2001-08-03) Effects of antihyperlipidemic drugs and diet plus exercise therapy in the treatment of patients with moderate hypercholesterolemia.H Nomura et al.Clinical therapeutics, 18(3), 477-482 (1996-05-01) Current medical aspects of pantethine.Zoltán Horváth et al.Ideggyogyaszati szemle, 62(7-8), 220-229 (2009-08-19) Comparison of the effects of pantethine and fursultiamine on plasma gastrointestinal peptide levels in healthy volunteers.Yosuke Suzuki et al.Biological & pharmaceutical bulletin, 34(10), 1640-1643 (2011-10-04) Pantethine. Monograph. Alternative medicine review : a journal of clinical therapeutic, 15(3), 279-282 (2010-12-16) Loss of cytoskeletal proteins and lens cell opacification in the selenite cataract model.H Matsushima et al.Experimental eye research, 64(3), 387-395 (1997-03-01) The effect of pantethine and ultraviolet-B radiation on the development of lenticular opacity in the emory mouse.N T Congdon et al.Current eye research, 20(1), 17-24 (1999-12-28) Impaired Coenzyme A metabolism affects histone and tubulin acetylation in Drosophila and human cell models of pantothenate kinase associated neurodegeneration.Katarzyna Siudeja et al.EMBO molecular medicine, 3(12), 755-766 (2011-10-15) The effects of pantethine on fatty liver and fat distribution.Y Osono et al.Journal of atherosclerosis and thrombosis, 7(1), 55-58 (2001-06-27) Pantethine rescues a Drosophila model for pantothenate kinase-associated neurodegeneration.Anil Rana et al.Proceedings of the National Academy of Sciences of the United States of America, 107(15), 6988-6993 (2010-03-31) Topical apolipoprotein A-1 may have a beneficial effect on the corneal epithelium in a mouse model of dry eye: a pilot study.Aung Kyaw Nyunt et al.Eye & contact lens, 34(5), 287-292 (2008-09-10) The role of nutraceutical supplements in the treatment of dyslipidemia.Mark Houston Journal of clinical hypertension (Greenwich, Conn.), 14(2), 121-132 (2012-01-27) Physiological and performance responses to supplementation with thiamin and pantothenic acid derivatives.M J Webster European journal of applied physiology and occupational physiology, 77(6), 486-491 (1998-07-03) Inhibition of acetyl-CoA carboxylase by cystamine may mediate the hypotriglyceridemic activity of pantethine.M F McCarty Medical hypotheses, 56(3), 314-317 (2001-05-22) Pantethine, a derivative of vitamin B(5) used as a nutritional supplement, favorably alters low-density lipoprotein cholesterol metabolism in low- to moderate-cardiovascular risk North American subjects: a triple-blinded placebo and diet-controlled investigation.John A Rumberger et al.Nutrition research (New York, N.Y.), 31(8), 608-615 (2011-09-20)

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