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Apoptosis signal-regulating kinase-1 aggravates ROS-mediated striatal degeneration in 3-nitropropionic acid-infused mice.Kyoung Joo Cho et al.Biochemical and biophysical research communications, 441(2), 280-285 (2013-09-12) MicroRNA-22 (miR-22) overexpression is neuroprotective via general anti-apoptotic effects and may also target specific Huntington's disease-related mechanisms.Ana Jovicic et al.PloS one, 8(1), e54222-e54222 (2013-01-26) Catechins protect neurons against mitochondrial toxins and HIV proteins via activation of the BDNF pathway.Samir Nath et al.Journal of neurovirology, 18(6), 445-455 (2012-08-14) Atypical features of Thermus thermophilus succinate:quinone reductase.Olga Kolaj-Robin et al.PloS one, 8(1), e53559-e53559 (2013-01-12) Dual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumorsLorendeau D, et al. Metabolic engineering, 43, 187-197 (2017) Sensitivity to neurotoxic stress is not increased in progranulin-deficient mice.Terri L Petkau et al.Neurobiology of aging, 34(11), 2548-2550 (2013-05-25) Astrocytes from cortex and striatum show differential responses to mitochondrial toxin and BDNF: implications for protection of striatal neurons expressing mutant huntingtin.Julieta Saba et al.Journal of neuroinflammation, 17(1), 290-290 (2020-10-08) Neuroprotective mechanisms of brain-derived neurotrophic factor against 3-nitropropionic acid toxicity: therapeutic implications for Huntington's disease.Chia-Lin Wu et al.Annals of the New York Academy of Sciences, 1201, 8-12 (2010-07-24) ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects.Yuanyuan Zhao et al.Nature communications, 10(1), 1371-1371 (2019-03-28) Mitochondrial dysfunction in neurodegeneration.J M Cooper et al.Journal of bioenergetics and biomembranes, 29(2), 175-183 (1997-04-01) The biochemistry of the metabolic poison propionate 3-nitronate and its conjugate acid, 3-nitropropionate.Kevin Francis et al.IUBMB life, 65(9), 759-768 (2013-07-31) Drp1 stabilizes p53 on the mitochondria to trigger necrosis under oxidative stress conditions in vitro and in vivo.Xing Guo et al.The Biochemical journal, 461(1), 137-146 (2014-04-25) 3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease.Emmanuel Brouillet et al.Journal of neurochemistry, 95(6), 1521-1540 (2005-11-23) Vinpocetine and α-tocopherol prevent the increase in DA and oxidative stress induced by 3-NPA in striatum isolated nerve endings.Nieves Herrera-Mundo et al.Journal of neurochemistry, 124(2), 233-240 (2012-11-06) Ionizing radiation induces mitochondrial reactive oxygen species production accompanied by upregulation of mitochondrial electron transport chain function and mitochondrial content under control of the cell cycle checkpoint.Tohru Yamamori et al.Free radical biology & medicine, 53(2), 260-270 (2012-05-15) No functional effects of embryonic neuronal grafts on motor deficits in a 3-nitropropionic acid rat model of advanced striatonigral degeneration (multiple system atrophy)Waldner R, et al. Neuroscience, 102(3), 581-592 (2001) The NMDA receptor subunit GluN3A protects against 3-nitroproprionic-induced striatal lesions via inhibition of calpain activation.Rebeca Martínez-Turrillas et al.Neurobiology of disease, 48(3), 290-298 (2012-07-18) Specific lesions in the extrapyramidal system of the rat brain induced by 3-nitropropionic acid (3-NPA)Pei G and Ebendal T Experimental Neurology, 132(1), 105-115 (1995) Scaf1 promotes respiratory supercomplexes and metabolic efficiency in zebrafish.Carolina García-Poyatos et al.EMBO reports, 21(7), e50287-e50287 (2020-06-05) Mitochondrial inhibitor models of Huntington's disease and Parkinson's disease induce zinc accumulation and are attenuated by inhibition of zinc neurotoxicity in vitro or in vivo.Christian T Sheline et al.Neuro-degenerative diseases, 11(1), 49-58 (2012-05-26) 3-Nitropropionic acid animal model and Huntington's disease.C V Borlongan et al.Neuroscience and biobehavioral reviews, 21(3), 289-293 (1997-05-01) Evidence for a transient peroxynitro acid in the reaction catalyzed by nitronate monooxygenase with propionate 3-nitronate.Crystal Smitherman et al.Biochemistry, 52(15), 2694-2704 (2013-03-28) Altered p53 and NOX1 activity cause bioenergetic defects in a SCA7 polyglutamine disease model.Abiodun Ajayi et al.Biochimica et biophysica acta, 1847(4-5), 418-428 (2015-02-04) Suppression of Cpn10 increases mitochondrial fission and dysfunction in neuroblastoma cells.So Jung Park et al.PloS one, 9(11), e112130-e112130 (2014-11-13) Involvement of the up-regulated FoxO1 expression in follicular granulosa cell apoptosis induced by oxidative stress.Ming Shen et al.The Journal of biological chemistry, 287(31), 25727-25740 (2012-06-07) Production of 3-nitropropionic acid by endophytic fungus Phomopsis longicolla isolated from Trichilia elegans A. JUSS ssp. elegans and evaluation of biological activity.Andressa Caroline Flores et al.World journal of microbiology & biotechnology, 29(5), 923-932 (2013-01-09) 3-Nitropropionic acid as a tool to study the mechanisms involved in Huntington's disease: past, present and future.Isaac Túnez et al.Molecules (Basel, Switzerland), 15(2), 878-916 (2010-03-26) DYT1 knock-in mice are not sensitized against mitochondrial complex-II inhibition.Nicole Bode et al.PloS one, 7(8), e42644-e42644 (2012-08-11) Inhibition of bioenergetics provides novel insights into recruitment of PINK1-dependent neuronal mitophagy.Yea Seul Shin et al.Journal of neurochemistry, 149(2), 269-283 (2019-01-22) Enhanced neuroprotective effect of fish oil in combination with quercetin against 3-nitropropionic acid induced oxidative stress in rat brain.K M Denny Joseph et al.Progress in neuro-psychopharmacology & biological psychiatry, 40, 83-92 (2012-09-11) Effects of chronic MPTP and 3-nitropropionic acid in nonhuman primates.E Brouillet et al.Current opinion in neurology, 8(6), 469-473 (1995-12-01) Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6.S Schüll et al.Cell death & disease, 6, e1691-e1691 (2015-03-15) Quantification of nitropropanoyl glucosides in karaka nuts before and after treatment.J J MacAskill et al.Food chemistry, 175, 543-548 (2015-01-13) 3-Nitropropionic acid modifies neurotrophin mRNA expression in the mouse striatum: 18S-rRNA is a reliable control gene for studies of the striatum.S Espíndola et al.Neuroscience bulletin, 28(5), 517-531 (2012-09-11) [Model of Huntington's disease induced with 3-nitropropionic acid].I Túnez et al.Revista de neurologia, 48(8), 430-434 (2009-04-03) Excitotoxicity is required for induction of oxidative stress and apoptosis in mouse striatum by the mitochondrial toxin, 3-nitropropionic acid.G W Kim et al.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 20(1), 119-129 (2000-01-05) Brief mitochondrial inhibition causes lasting changes in motor behavior and corticostriatal synaptic physiology in the Fischer 344 rat.G Akopian et al.Neuroscience, 215, 149-159 (2012-05-05) Systemic, but not intraparenchymal, administration of 3-nitropropionic acid mimics the neuropathology of Huntington's disease: a speculative explanation.C V Borlongan et al.Neuroscience research, 28(3), 185-189 (1997-07-01) Rhes deletion is neuroprotective in the 3-nitropropionic acid model of Huntington's disease.Robert G Mealer et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(9), 4206-4210 (2013-03-01) The role of mitochondrial dysfunction and neuronal nitric oxide in animal models of neurodegenerative diseases.J B Schulz et al.Molecular and cellular biochemistry, 174(1-2), 193-197 (1997-10-06) Toxicity and metabolism of the conjugates of 3-nitropropanol and 3-nitropropionic acid in forages poisonous to livestock.Robin C Anderson et al.Journal of agricultural and food chemistry, 53(6), 2344-2350 (2005-03-17) 3-Nitropropionic acid-exogenous animal neurotoxin and possible human striatal toxin.A C Ludolph et al.The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 18(4), 492-498 (1991-11-01) 8-Oxoguanine causes neurodegeneration during MUTYH-mediated DNA base excision repair.Zijing Sheng et al.The Journal of clinical investigation, 122(12), 4344-4361 (2012-11-13) 2-deoxy-D-glucose enhances anesthetic effects in mice.Hui Wang et al.Anesthesia and analgesia, 120(2), 312-319 (2014-11-13) Mouse Models of Dystonia Animal Models of Movement Disorders (2005) Expression of PUMA in Follicular Granulosa Cells Regulated by FoxO1 Activation During Oxidative Stress.Ze-Qun Liu et al.Reproductive sciences (Thousand Oaks, Calif.), 22(6), 696-705 (2014-11-27) Alpha-mangostin induces changes in glutathione levels associated with glutathione peroxidase activity in rat brain synaptosomes.Berenice Márquez-Valadez et al.Nutritional neuroscience, 15(5), 13-19 (2012-12-13) Potential neuroprotective effects of hesperidin on 3-nitropropionic acid-induced neurotoxicity in rats.Esther T Menze et al.Neurotoxicology, 33(5), 1265-1275 (2012-08-02) Korean red ginseng ameliorates acute 3-nitropropionic acid-induced cochlear damage in mice.Chunjie Tian et al.Neurotoxicology, 34, 42-50 (2012-11-21) Magnetic resonance imaging and spectroscopy in assessing 3-nitropropionic acid-induced brain lesions: an animal model of Huntington's disease.Wang-Tso Lee et al.Progress in neurobiology, 72(2), 87-110 (2004-04-06) Naringin modulates oxidative stress and inflammation in 3-nitropropionic acid-induced neurodegeneration through the activation of nuclear factor-erythroid 2-related factor-2 signalling pathway.K Gopinath et al.Neuroscience, 227, 134-143 (2012-08-09) The protective effect of Egb 761 against 3-nitropropionic acid-induced hearing loss: the role of sirtuin 1Chang M Y, et al. Clinical and Experimental Otorhinolaryngology, 11(1), 9-9 (2018) Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma.Richa Bajpai et al.Nature communications, 11(1), 1228-1228 (2020-03-08) Succinobucol versus probucol: higher efficiency of succinobucol in mitigating 3-NP-induced brain mitochondrial dysfunction and oxidative stress in vitro.Dirleise Colle et al.Mitochondrion, 13(2), 125-133 (2013-01-22) Quercetin supplementation is effective in improving mitochondrial dysfunctions induced by 3-nitropropionic acid: implications in Huntington's disease.Rajat Sandhir et al.Biochimica et biophysica acta, 1832(3), 421-430 (2012-12-12) Optimal dosages of fluoxetine in the treatment of hypoxic brain injury induced by 3-nitropropionic acid: implications for the adjunctive treatment of patients after acute ischemic stroke.Bing-Gen Zhu et al.CNS neuroscience & therapeutics, 18(7), 530-535 (2012-04-21) Heat shock transcription factor-1 suppresses apoptotic cell death and ROS generation in 3-nitropropionic acid-stimulated striatal cells.Yong-Joon Choi et al.Molecular and cellular biochemistry, 375(1-2), 59-67 (2012-12-12) Organoselenium bis selenide attenuates 3-nitropropionic acid-induced neurotoxicity in rats.Cristiani F Bortolatto et al.Neurotoxicity research, 23(3), 214-224 (2012-06-29)

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