Melting point	62-64 ºC
Water Solubility	100 g/L (20 ºC)
Boiling point	233 ºC
Density	1.04

Symbol(GHS)	Xn
Hazard Codes	R20/22

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Screening assay of very long chain fatty acids in human plasma with multiwalled carbon nanotube-based surface-assisted laser desorption/ionization mass spectrometry.Wei-Yi Hsu et al.Analytical chemistry, 82(16), 6814-6820 (2010-08-14) Lovastatin in X-linked adrenoleukodystrophy.Marc Engelen et al.The New England journal of medicine, 362(3), 276-277 (2010-01-22) Early oxidative damage underlying neurodegeneration in X-adrenoleukodystrophy.Stéphane Fourcade et al.Human molecular genetics, 17(12), 1762-1773 (2008-03-18) Astrocytes and mitochondria from adrenoleukodystrophy protein (ABCD1)-deficient mice reveal that the adrenoleukodystrophy-associated very long-chain fatty acids target several cellular energy-dependent functions.Nicol Kruska et al.Biochimica et biophysica acta, 1852(5), 925-936 (2015-01-15) Peroxisomal bifunctional enzyme deficiency.P A Watkins et al.The Journal of clinical investigation, 83(3), 771-777 (1989-03-01) Bezafibrate lowers very long-chain fatty acids in X-linked adrenoleukodystrophy fibroblasts by inhibiting fatty acid elongation.Marc Engelen et al.Journal of inherited metabolic disease, 35(6), 1137-1145 (2012-03-27) Lipidomics reveals a remarkable diversity of lipids in human plasma.Oswald Quehenberger et al.Journal of lipid research, 51(11), 3299-3305 (2010-07-31) The effect of Lorenzo's oil on oxidative stress in X-linked adrenoleukodystrophy.Marion Deon et al.Journal of the neurological sciences, 247(2), 157-164 (2006-06-06) Combined liquid chromatography-tandem mass spectrometry as an analytical method for high throughput screening for X-linked adrenoleukodystrophy and other peroxisomal disorders: preliminary findings.Walter C Hubbard et al.Molecular genetics and metabolism, 89(1-2), 185-187 (2006-07-11) Phospholipids profiling and outcome of peritoneal dialysis patients.Wen Tang et al.Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 19(6), 505-508 (2014-08-01) Follow-up of 89 asymptomatic patients with adrenoleukodystrophy treated with Lorenzo's oil.Hugo W Moser et al.Archives of neurology, 62(7), 1073-1080 (2005-07-13) Is subclinical adrenal failure in adrenoleukodystrophy/adrenomyeloneuropathy reversible?M Cappa et al.Journal of endocrinological investigation, 34(10), 753-756 (2011-03-15) Adrenomyeloneuropathy presenting as Addison's disease in childhood.A Sadeghi-Nejad et al.The New England journal of medicine, 322(1), 13-16 (1990-01-04) Active components from Siberian ginseng (Eleutherococcus senticosus) for protection of amyloid β(25-35)-induced neuritic atrophy in cultured rat cortical neurons.Yanjing Bai et al.Journal of natural medicines, 65(3-4), 417-423 (2011-02-09) The uptake of trehalose glycolipids by macrophages is independent of Mincle.Kristel Kodar et al.Chembiochem : a European journal of chemical biology, 16(4), 683-693 (2015-02-04) RNAi-mediated silencing of ABCD3 gene expression in rat C6 glial cells: a model system to study PMP70 function.Rita Di Benedetto et al.Neurochemistry international, 52(6), 1106-1113 (2008-01-08) High levels of saturated very long-chain fatty acid (hexacosanoic acid; C26:0) in whole blood are associated with metabolic syndrome in Japanese men.Atsumi Kume et al.Diabetes research and clinical practice, 80(2), 259-264 (2008-02-05) A fast method for the identification of Mycobacterium tuberculosis in sputum and cultures based on thermally assisted hydrolysis and methylation followed by gas chromatography-mass spectrometry.Erwin Kaal et al.Journal of chromatography. A, 1216(35), 6319-6325 (2009-07-28) Odd-numbered very-long-chain fatty acids from the microbial, animal and plant kingdoms.Tomás Rezanka et al.Progress in lipid research, 48(3-4), 206-238 (2009-04-02) The inflammatory response in acyl-CoA oxidase 1 deficiency (pseudoneonatal adrenoleukodystrophy).H I El Hajj et al.Endocrinology, 153(6), 2568-2575 (2012-04-18) Abcd2 is a strong modifier of the metabolic impairments in peritoneal macrophages of ABCD1-deficient mice.Zahid Muneer et al.PloS one, 9(9), e108655-e108655 (2014-09-26) A simple and sensitive liquid chromatographic method for the analysis of free docosanoic, tetracosanoic and hexacosanoic acids in human plasma as fluorescent derivatives.Tang-Chia Chung et al.Analytica chimica acta, 611(1), 113-118 (2008-02-27) Plasmalogens participate in very-long-chain fatty acid-induced pathology.Pedro Brites et al.Brain : a journal of neurology, 132(Pt 2), 482-492 (2008-11-22) A two-year trial of oleic and erucic acids ("Lorenzo's oil") as treatment for adrenomyeloneuropathy.P Aubourg et al.The New England journal of medicine, 329(11), 745-752 (1993-09-09) X-linked adrenoleukodystrophy: clinical course and minimal incidence in South Brazil.Laura Bannach Jardim et al.Brain & development, 32(3), 180-190 (2009-03-10) Very long chain fatty acids activate NADPH oxidase in human dermal fibroblasts.Gursev S Dhaunsi et al.Cell biochemistry and function, 23(1), 65-68 (2004-11-27) Phytochemical investigation of the fruit peels of Citrus reticulata Blanco.M Aasim Khan et al.Natural product research, 24(7), 610-620 (2010-04-20) Fast diffusion of very long chain saturated fatty acids across a bilayer membrane and their rapid extraction by cyclodextrins: implications for adrenoleukodystrophy.Biju K Pillai et al.The Journal of biological chemistry, 284(48), 33296-33304 (2009-10-06) Concentrations of very long-chain fatty acid in whole blood are associated with cardiovascular risk factors in children.Aya Okahashi et al.Clinica chimica acta; international journal of clinical chemistry, 401(1-2), 141-143 (2009-01-13) Down-regulation of fatty acid synthase increases the resistance of Saccharomyces cerevisiae cells to H2O2.Ana C Matias et al.Free radical biology & medicine, 43(10), 1458-1465 (2007-10-16) Very long chain fatty acid levels in patients diagnosed with multiple sclerosis.Alastair Wilkins et al.Multiple sclerosis (Houndmills, Basingstoke, England), 15(12), 1525-1527 (2009-12-08) [Studies on the constituents from the stems of Spatholobus suberectus].Jun Cheng et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 28(12), 1153-1155 (2004-12-25) Development and application of a comparative fatty acid analysis method to investigate voriconazole-induced hepatotoxicity.Guan-yuan Chen et al.Clinica chimica acta; international journal of clinical chemistry, 438, 126-134 (2014-08-26) Stereoselective pH Responsive Peptide Dendrimers for siRNA Transfection.Marc Heitz et al.Bioconjugate chemistry, 30(8), 2165-2182 (2019-08-10) Hexacosanoic and docosanoic acids plasma levels in patients with cerebral childhood and asymptomatic X-linked adrenoleukodystrophy: Lorenzo's oil effect.Marion Deon et al.Metabolic brain disease, 23(1), 43-49 (2007-11-21) Effect of DMSO, urea and ethanol on hydration of stratum corneum model membrane based on short-chain length ceramide [AP].N Yu Samoylova et al.Chemistry and physics of lipids, 221, 1-7 (2019-03-03) Investigation of stratum corneum lipid model membranes with free fatty acid composition by neutron diffraction.Natalia Yu Ryabova et al.European biophysics journal : EBJ, 39(8), 1167-1176 (2009-12-17) The prenatal diagnosis of adrenoleukodystrophy. Demonstration of increased hexacosanoic acid levels in cultured amniocytes and fetal adrenal gland.H W Moser et al.Pediatric research, 16(3), 172-175 (1982-03-01) [Studies on chemical constituents of Heterosmilax yunnanensis].Wen-jie Qin et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 30(8), 959-961 (2007-12-14)

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