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3'-Hydroxyacetophenone | CAS:121-71-1
3'-Hydroxyacetophenone
  • Name:3'-Hydroxyacetophenone
  • CAS:121-71-1
  • Synonyms:m-Hydroxyacetophenone; 3-Acetylphenol
  • Molecular Formula:C8H8O2
  • Molecular Weight:136.15
  • EINESC:204-494-0

Description

Properties

Melting point 94-97 ºC
Boiling point 296 ºC
Density 1.10

Safety

Symbol(GHS) Xi
Hazard Codes R36/37/38
SDS/MSDS S26;S37/39

SDS

Source SDS/MSDS Samples
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Synthetic Route
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Articles
Peer-Reviewed Papers
A protocol to 2-aminobenzimidazoles via copper-catalyzed cascade addition and cyclization of o-haloanilines and carbodiimides.Fei Wang et al.The Journal of organic chemistry, 76(9), 3174-3180 (2011-03-19) Novel small molecule bradykinin B1 receptor antagonists. Part 2: 5-membered diaminoheterocycles.Gunther Zischinsky et al.Bioorganic & medicinal chemistry letters, 20(3), 1229-1232 (2009-12-18) One-pot, two-step synthesis of imidazo[1,2-a]benzimidazoles via a multicomponent [4 + 1] cycloaddition reaction.Ya-Shan Hsiao et al.ACS combinatorial science, 15(10), 551-555 (2013-09-11) Synthesis and QSAR studies of novel 1-substituted-2-aminobenzimidazoles derivatives.Xuan Guida et al.European journal of medicinal chemistry, 41(9), 1080-1083 (2006-07-11) Catalyst-controlled chemoselective arylation of 2-aminobenzimidazoles.Satoshi Ueda et al.Angewandte Chemie (International ed. in English), 51(41), 10364-10367 (2012-09-13) Programmed enzyme-mimic hydrolysis of a choline carbonate by a metal-free 2-aminobenzimidazole-based cavitand.Bartolomé Soberats et al.Organic letters, 16(3), 840-843 (2014-01-15) One scaffold, three binding modes: novel and selective pteridine reductase 1 inhibitors derived from fragment hits discovered by virtual screening.Chidochangu P Mpamhanga et al.Journal of medicinal chemistry, 52(14), 4454-4465 (2009-06-17) Probing a 2-aminobenzimidazole library for binding to RNA internal loops via two-dimensional combinatorial screening.Sai Pradeep Velagapudi et al.ACS chemical biology, 7(11), 1902-1909 (2012-09-11) Experimental and theoretical (DFT) characterization of the excited states and N-centered radical species derived from 2-aminobenzimidazole, the core substructure of a family of bioactive compounds.Verónica Viudes et al.The journal of physical chemistry. B, 114(19), 6608-6613 (2010-04-29) Simultaneous analysis of thiabendazole, carbendazim and 2-aminobenzimidazole in concentrated fruit juices by liquid chromatography after a single mix-mode solid-phase extraction cleanup.Xiao S Liu et al.Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 44(6), 591-597 (2010-02-26) A 2-aminobenzimidazole that inhibits and disperses gram-positive biofilms through a zinc-dependent mechanism.Steven A Rogers et al.Journal of the American Chemical Society, 131(29), 9868-9869 (2009-07-23) Aggregation of 2-aminobenzimidazole--a combined experimental and theoretical investigation.Silvia E Angelova et al.Chemphyschem : a European journal of chemical physics and physical chemistry, 12(9), 1747-1755 (2011-05-14) Removal of nonspecific binding proteins from cell and tissue extracts using 2-aminobenzimidazole-tethered affinity resin.E Molnár et al.Die Pharmazie, 66(9), 662-665 (2011-10-27) 2-Aminobenzimidazoles as potent ITK antagonists: trans-stilbene-like moieties targeting the kinase specificity pocket.Ho Yin Lo et al.Bioorganic & medicinal chemistry letters, 18(23), 6218-6221 (2008-10-22) Identification of 2-aminobenzimidazoles as potent melanin-concentrating hormone 1-receptor (MCH1R) antagonists.Minoru Moriya et al.Bioorganic & medicinal chemistry letters, 19(13), 3568-3572 (2009-05-22) 2-Aminobenzimidazole derivatives strongly inhibit and disperse Pseudomonas aeruginosa biofilms.Reto Frei et al.Angewandte Chemie (International ed. in English), 51(21), 5226-5229 (2012-04-11) The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii.Robert W Huigens et al.Bioorganic & medicinal chemistry, 18(2), 663-674 (2010-01-02) Chemical biology strategy reveals pathway-selective inhibitor of NF-kappaB activation induced by protein kinase C.Ranxin Shi et al.ACS chemical biology, 5(3), 287-299 (2010-02-10) Experimental and theoretical studies on the mechanism of photochemical hydrogen transfer from 2-aminobenzimidazole to nπ* and ππ* aromatic ketones.Dolors Jornet et al.The journal of physical chemistry. B, 114(36), 11920-11926 (2010-08-26) 2-Aminobenzimidazoles as potent Aurora kinase inhibitors.Min Zhong et al.Bioorganic & medicinal chemistry letters, 19(17), 5158-5161 (2009-08-04) Synthesis of tetrahydrobenzimidazo[1,2-b]quinazolin-1(2H)-one and tetrahydro-1,2,4-triazolo[5,1-b]quinazolin-8(4H)-one ring systems under solvent-free conditions.Ahmad Shaabani et al.Combinatorial chemistry & high throughput screening, 9(10), 771-776 (2006-12-16) Toward bifunctional antibody catalysis.Kazuya Kikuchi et al.Bioorganic & medicinal chemistry, 14(18), 6189-6196 (2006-06-20) Brain-penetrating 2-aminobenzimidazole H(1)-antihistamines for the treatment of insomnia.Timothy Coon et al.Bioorganic & medicinal chemistry letters, 19(15), 4380-4384 (2009-06-26) Discovery and characterization of 2-aminobenzimidazole derivatives as selective NOD1 inhibitors.Ricardo G Correa et al.Chemistry & biology, 18(7), 825-832 (2011-08-02) Molecular structure, vibrational spectroscopic, first-order hyperpolarizability and HOMO, LUMO studies of 2-aminobenzimidazole.S Sudha et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 84(1), 184-195 (2011-10-11) Site-specific cleavage of RNA by a metal-free artificial nuclease attached to antisense oligonucleotides.Claudio Gnaccarini et al.Journal of the American Chemical Society, 128(24), 8063-8067 (2006-06-15) Synthesis and biological evaluation of new non-imidazole H3-receptor antagonists of the 2-aminobenzimidazole series.Mirko Rivara et al.Bioorganic & medicinal chemistry, 14(5), 1413-1424 (2005-11-03) Molecular modeling of some 1H-benzimidazole derivatives with biological activity against Entamoeba histolytica: a comparative molecular field analysis study.Fabian López-Vallejo et al.Bioorganic & medicinal chemistry, 15(2), 1117-1126 (2006-11-01) Zinc fingered: new compounds that thwart gram-positive biofilm formation by sequestering zinc.Dinty J Musk Chembiochem : a European journal of chemical biology, 11(6), 758-760 (2010-03-02)
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