Melting point	-38 ºC
Water Solubility	0.1 g/100 mL (20 ºC)
Boiling point	174-181 ºC
Flash point	71 ºC
Density	0.821
Refractive index	1.425-1.427

SDS/MSDS	S24/25

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Peer-Reviewed Papers

Determination of FAD-binding domain in flavin-containing monooxygenase 1 (FMO1).A Kubo et al.Archives of biochemistry and biophysics, 345(2), 271-277 (1997-10-06) Protein targets of thioacetamide metabolites in rat hepatocytes.Yakov M Koen et al.Chemical research in toxicology, 26(4), 564-574 (2013-03-08) Structure-activity relationships for a series of thiobenzamide influenza fusion inhibitors derived from 1,3,3-trimethyl-5-hydroxy-cyclohexylmethylamine.Kuo Long Yu et al.Bioorganic & medicinal chemistry letters, 12(23), 3379-3382 (2002-11-07) Hydrogen sulfide enhances ulcer healing in rats.John L Wallace et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 21(14), 4070-4076 (2007-07-20) Covalent modification of microsomal lipids by thiobenzamide metabolites in vivo.Tao Ji et al.Chemical research in toxicology, 20(4), 701-708 (2007-03-27) Thiobenzamide-induced hepatotoxicity: effects of substituents and route of administration on the nature and extent of liver injury.S J Grossman et al.Toxicology and applied pharmacology, 111(3), 388-408 (1991-12-01) Effects of the herbicide chlorthiamid on the olfactory mucosa.C Eriksson et al.Toxicology letters, 76(3), 203-208 (1995-04-01) Involvement of CYP3A1, 2B1, and 2E1 in C-8 hydroxylation and CYP 1A2 and flavin-containing monooxygenase in N-demethylation of caffeine; identified by using inducer treated rat liver microsomes that are characterized with testosterone metabolic patterns.W G Chung et al.Chemico-biological interactions, 113(1), 1-14 (1998-06-19) Potent inhibition of alcohol self-administration in alcohol-preferring rats by a κ-opioid receptor antagonist.John R Cashman et al.The Journal of pharmacology and experimental therapeutics, 350(1), 171-180 (2014-05-13) Conformational polymorphism in N-(4'-methoxyphenyl)- 3-bromothiobenzamide.Anastasiya Bashkirava et al.Chemistry, an Asian journal, 2(4), 530-538 (2007-04-19) Placental peroxidase--further purification of the enzyme and oxidation of thiobenzamide.P Joseph et al.Placenta, 14(3), 309-319 (1993-05-01) Flavin-containing monooxygenase activity can be inhibited by nitric oxide-mediated S-nitrosylation.Seung-Duk Ryu et al.Life sciences, 75(21), 2559-2572 (2004-09-15) Chemical Research in Toxicology. In this issue. Chemical research in toxicology, 21(7), 1320-1321 (2008-07-22) Protein targets of reactive metabolites of thiobenzamide in rat liver in vivo.Keisuke Ikehata et al.Chemical research in toxicology, 21(7), 1432-1442 (2008-06-13) Role of lipoxygenase in xenobiotic metabolism: sulfoxidation of thiobenzamide by purified soybean lipoxygenase.A K Naidu et al.Research communications in chemical pathology and pharmacology, 71(2), 175-188 (1991-02-01) Cytotoxic activity of 3-(5-phenyl-3H-[1,2,4]dithiazol-3-yl)chromen-4-ones and 4-oxo-4H-chromene-3-carbothioic acid N-phenylamides.Tilak Raj et al.European journal of medicinal chemistry, 45(2), 790-794 (2009-11-27) Presence of flavin-containing monooxygenase in rat brain.S Bhamre et al.Biochemical pharmacology, 42(2), 442-444 (1991-07-05) Relative hepatotoxicity of 2-(substituted phenyl)thiazoles and substituted thiobenzamides in mice: evidence for the involvement of thiobenzamides as ring cleavage metabolites in the hepatotoxicity of 2-phenylthiazoles.T Mizutani et al.Toxicology letters, 85(2), 101-105 (1996-05-01) Metabolism of thioamides by Ralstonia pickettii TA.Anthony G Dodge et al.Applied and environmental microbiology, 72(12), 7468-7476 (2006-09-26) Persistent chemopreventive effect of S-adenosyl-L-methionine on the development of liver putative preneoplastic lesions induced by thiobenzamide in diethylnitrosamine-initiated rats.M M Simile et al.Carcinogenesis, 17(7), 1533-1537 (1996-07-01) Induction of flavin-containing monooxygenase (FMO1) by a polycyclic aromatic hydrocarbon, 3-methylcholanthrene, in rat liver.W G Chung et al.Molecules and cells, 7(6), 738-741 (1998-03-24) ETM-ANN approach application for thiobenzamide and quinolizidine derivatives.M Saracoglu et al.Journal of biomedicine & biotechnology, 2010, doi:10-doi:10 (2010-09-28) Gender differences in hepatic expression of flavin-containing monooxygenase isoforms (FMO1, FMO3, and FMO5) in mice.J G Falls et al.Journal of biochemical toxicology, 10(3), 171-177 (1995-06-01) 2,2'-Dithiobisbenzamides and 2-benzisothiazolones, two new classes of antiretroviral agents: SAR and mechanistic considerations.J M Domagala et al.Drug design and discovery, 15(1), 49-61 (1997-05-01) Facile synthesis of nitriles via manganese oxide promoted oxidative dehydrosulfurization of primary thioamides.Kazuya Yamaguchi et al.Chemical communications (Cambridge, England), 48(91), 11247-11249 (2012-10-17) Peroxidase-catalyzed S-oxygenation: mechanism of oxygen transfer for lactoperoxidase.D R Doerge et al.Biochemistry, 30(37), 8960-8964 (1991-09-17) Possible role of the acetone-inducible cytochrome P-450IIE1 in the metabolism and hepatotoxicity of thiobenzamide.E Chieli et al.Archives of toxicology, 64(2), 122-127 (1990-01-01) Determination of p-methylthiobenzamide and p-methylthiobenzamide-S-oxide from rat plasma using solid-phase extraction and high-performance liquid chromatography.V P Davidson et al.Journal of chromatography, 567(1), 213-220 (1991-06-14)

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