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Synthetic Route

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Articles

Peer-Reviewed Papers

Isolation and structural elucidation of abietic acid as the main adulterant in an herbal drug for the treatment of psoriasis.Yi He et al.Journal of pharmaceutical and biomedical analysis, 66, 345-348 (2012-04-10) Antiparasitic, nematicidal and antifouling constituents from Juniperus berries.Volodymyr Samoylenko et al.Phytotherapy research : PTR, 22(12), 1570-1576 (2008-12-11) Abietic acid attenuates IL-1β-induced inflammation in human osteoarthritis chondrocytes.Sining Kang et al.International immunopharmacology, 64, 110-115 (2018-09-02) Determination of resin acids during production of wood pellets--a comparison of HPLC/ESI-MS with the GC/FID MDHS 83/2 method.Sara Axelsson et al.Journal of environmental monitoring : JEM, 13(10), 2940-2945 (2011-08-30) A large gene cluster in Burkholderia xenovorans encoding abietane diterpenoid catabolism.Daryl J Smith et al.Journal of bacteriology, 189(17), 6195-6204 (2007-06-26) A new abietic acid-type diterpene glucoside from the needles of Pinus densiflora.Mee Jung Jung et al.Archives of pharmacal research, 32(12), 1699-1704 (2010-02-18) Rosin-based acid anhydrides as alternatives to petrochemical curing agents.Liu X, et al. Green Chemistry, 11(7), 1018-1025 (2009) Radial distribution of wood extractives in European larch Larix decidua by TOF-SIMS imaging.Tingting Fu et al.Phytochemistry, 150, 31-39 (2018-03-14) Ancient wood of the Acqualadrone rostrum: materials history through gas chromatography/mass spectrometry and sulfur X-ray absorption spectroscopy.Patrick Frank et al.Analytical chemistry, 84(10), 4419-4428 (2012-05-02) Cytotoxic, immunomodulatory, antimycotic, and antiviral activities of semisynthetic 14-hydroxyabietane derivatives and triptoquinone C-4 epimersZapata B, et al. MedChemComm, 4(9), 1239-1246 (2013) Picosecond structural relaxation of abietic acid based amine end capped para-phenylenevinylene trimers in solution.Roberto E Di Paolo et al.Chemphyschem : a European journal of chemical physics and physical chemistry, 9(15), 2214-2220 (2008-10-03) Antioxidant activity of a catechol derived from abietic acidJustino GC, et al. Journal of Agricultural and Food Chemistry, 54(2), 342-348 (2006) [Study on determination methods for abietic acid in fake Myrrha].Cong Xiao et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 35(8), 1237-1241 (2013-01-17) Resin acids as inducible chemical defences of pine seedlings against chewing insects.Xosé López-Goldar et al.PloS one, 15(5), e0232692-e0232692 (2020-05-02) Regioselective routes towards 14-hydroxyabietane diterpenes. A formal synthesis of immunosuppressant (−)-triptolide from (+)-abietic acid.Alvarez-Manzaneda E, et al. Tetrahedron, 63(45), 11204-11212 (2007) Resin acid conversion with CYP105A1: an enzyme with potential for the production of pharmaceutically relevant diterpenoids.Simon Janocha et al.Chembiochem : a European journal of chemical biology, 14(4), 467-473 (2013-02-02) G. Buchbauer Monatshefte fur Chemie / Chemical Monthly, 116, 1345-1345 (1985) Synthesis and biological evaluation of dehydroabietic acid derivatives.Miguel A González et al.European journal of medicinal chemistry, 45(2), 811-816 (2009-11-07) Anti-staphylococcal activity of C-methyl flavanones from propolis of Australian stingless bees (Tetragonula carbonaria) and fruit resins of Corymbia torelliana (Myrtaceae).C F Massaro et al.Fitoterapia, 95, 247-257 (2014-04-08) Abietic acid has an anti-obesity effect in mice fed a high-fat diet.Kwang-Hyun Hwang et al.Journal of medicinal food, 14(9), 1052-1056 (2011-08-05) Fragrance material review on abietyl acetate.S P Bhatia et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 46 Suppl 12, S28-S29 (2008-10-11) Intermolecular interaction and solid state characterization of abietic acid/chitosan solid dispersions possessing antimicrobial and antioxidant properties.Valentina Cuzzucoli Crucitti et al.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 125, 114-123 (2018-01-26) G. Buchbauer et al.Scientia Pharmaceutica, 53, 173-173 (1985) Structural effects on the bioactivity of dehydroabietic acid derivativesGigante B, et al. Planta Medica, 68(08), 680-684 (2002) Temperature dependent rapid annealing effect induces amorphous aggregation of human serum albumin.Mohd Ishtikhar et al.International journal of biological macromolecules, 82, 844-855 (2015-11-10) The need for enzymatic steering in abietic acid biosynthesis: gas-phase chemical dynamics simulations of carbocation rearrangements on a bifurcating potential energy surface.Matthew R Siebert et al.Journal of the American Chemical Society, 133(21), 8335-8343 (2011-05-10) Synthesis and biological evaluation of dehydroabietic acid derivatives.Gonzalez M A, et al. European Journal of Medicinal Chemistry, 45(2), 811-816 (2010) Inducible pine rosin defense mediates interactions between an invasive insect-fungal complex and newly acquired sympatric fungal associates.Chihang Cheng et al.Integrative zoology, 10(5), 453-464 (2015-05-06) Allergic contact dermatitis in a violinist. The role of abietic acid--a sensitizer in rosin (colophony)--as the causative agent.A A Fisher Cutis, 27(5), 466-466 (1981-05-01) Synthesis of biobased epoxy and curing agents using rosin and the study of cure reactions.Wang H, et al. Green Chemistry, 10(11), 1190-1196 (2008) Tape-stripping as a method for measuring dermal exposure to resin acids during wood pellet production.Kåre Eriksson et al.Journal of environmental monitoring : JEM, 10(3), 345-352 (2008-04-09) Dehydroabietic acid alleviates high fat diet-induced insulin resistance and hepatic steatosis through dual activation of PPAR-γ and PPAR-α.Zhishen Xie et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 127, 110155-110155 (2020-05-16) Cell transformation activities of abietic acid and dehydroabietic acid: safety assessment of possible contaminants in paper and paperboard for food contact use.K Ohmori et al.Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 26(4), 568-573 (2009-08-15) [Determination of dehydroabietic acid and abietic acid in aqueous alkali extract of Liquidambaris Resina by HPLC].Ying-Feng Wang et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(1), 57-59 (2013-04-20) BrtB is an O-alkylating enzyme that generates fatty acid-bartoloside esters.João P A Reis et al.Nature communications, 11(1), 1458-1458 (2020-03-21) Distinct roles for two CYP226 family cytochromes P450 in abietane diterpenoid catabolism by Burkholderia xenovorans LB400.Daryl J Smith et al.Journal of bacteriology, 190(5), 1575-1583 (2007-12-25) Applicability of amino acid derivative reactivity assay for prediction of skin sensitization by combining multiple alternative methods to evaluate key events.Yusuke Yamamoto et al.The Journal of toxicological sciences, 44(9), 585-600 (2019-09-03) Chemical composition of natural colophony from Pinus brutia and comparison with synthetic colophony.Ahmet C Gören et al.Natural product communications, 5(11), 1729-1732 (2011-01-11) Evaluation of skin sensitization potential of chemicals by local lymph node assay using 5-bromo-2-deoxyuridine with flow cytometry.Byeol-I Han et al.Regulatory toxicology and pharmacology : RTP, 107, 104401-104401 (2019-06-04) Design and characterization of an efficient CYP105A1-based whole-cell biocatalyst for the conversion of resin acid diterpenoids in permeabilized Escherichia coli.Simon Janocha et al.Applied microbiology and biotechnology, 97(17), 7639-7649 (2013-06-25) Mechanism of Formation of the Nonstandard Product in the Prenyltransferase Reaction of the G115T Mutant of FtmPT1: A Case of Reaction Dynamics Calling the Shots?Li-Li Pan et al.Biochemistry, 56(24), 2995-3007 (2017-06-02) Lipophilic extracts from needles and defoliated twigs of Pinus pumila from two different populations.Alexander V Shpatov et al.Chemistry & biodiversity, 10(2), 198-208 (2013-02-19) Molecular underpinnings of methyl jasmonate-induced resistance in Norway spruce.Melissa H Mageroy et al.Plant, cell & environment, 43(8), 1827-1843 (2020-04-24) Nanolipolee-007, a novel nanoparticle-based drug containing leelamine for the treatment of melanoma.Raghavendra Gowda et al.Molecular cancer therapeutics, 13(10), 2328-2340 (2014-08-02) Heterogeneous OH oxidation of biomass burning organic aerosol surrogate compounds: assessment of volatilisation products and the role of OH concentration on the reactive uptake kinetics.Jonathan H Slade et al.Physical chemistry chemical physics : PCCP, 15(16), 5898-5915 (2013-03-15) Synthesis and biological evaluation of abietic acid derivatives.Miguel A González et al.European journal of medicinal chemistry, 44(6), 2468-2472 (2009-02-17) Identification of CYP106A2 as a regioselective allylic bacterial diterpene hydroxylase.Sabrina Bleif et al.Chembiochem : a European journal of chemical biology, 12(4), 576-582 (2011-01-29) Antimicrobial and antibiofilm effects of abietic acid on cariogenic Streptococcus mutans.Yuki Ito et al.Odontology, 108(1), 57-65 (2019-09-15) Allergic contact dermatitis from depilatory wax.Maria Michela Lauriola et al.Dermatitis : contact, atopic, occupational, drug, 23(3), 126-127 (2012-06-02) Development of ultrasonic-assisted closed in-syringe extraction and derivatization for the determination of labile abietic acid and dehydroabietic acid in cosmetics.Jianjun Liu et al.Journal of chromatography. A, 1371, 20-29 (2014-12-03) Isolation, chemical, and biotransformation routes of labdane-type diterpenes.Luís M T Frija et al.Chemical reviews, 111(8), 4418-4452 (2011-05-31) Synthesis of (+)-amberketal and its analog from L-abietic acid.Yadav J S, et al. Tetrahedron, 63(39), 9896-9902 (2007) Preparation and application of abietic acid-derived optically active helical polymers and their chiral hydrogels.Fei Yao et al.Bioresource technology, 129, 58-64 (2012-12-13) In vitro RHE skin sensitisation assays: Applicability to challenging substances.A Mehling et al.Regulatory toxicology and pharmacology : RTP, 108, 104473-104473 (2019-09-09) Rosin-derived imide-diacids as epoxy curing agents for enhanced performance.Liu X, et al Bioresource Technology, 101(7), 2520-2524 (2010) H. Okawara et al. Tetrahedron Letters, 23, 1087-1087 (1982) S. Valverde et al. Tetrahedron, 42, 573-573 (1986)

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