Melting point	120-124 ºC
Water Solubility	1 g/L (20 ºC)
Boiling point	285-286 ºC
Flash point	160 ºC

Symbol(GHS)	Xn;N
Hazard Codes	R20/22;R50
SDS/MSDS	S24/25;S61

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Effects of the 5HT antagonist cyproheptadine on neuropsychological function in chronic schizophreniaChaudhry IB, et al. Schizophrenia Research, 53(1-2), 17-24 (2002) Suppressive effects of antihistaminic and/or anti-PAF agents on passive anaphylactic shock in mice sensitized with allogeneic monoclonal IgE and IgG1 antibodies and hyperimmune serum.S Kimura et al.Immunological investigations, 27(6), 379-393 (1998-12-09) Serotonin effects in the crab Neohelice granulata: possible involvement of two types of receptors in peripheral tissuesInohara E T S, et al. Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology, 185, 80-90 (2015) Comparative anticholinergic activities of 10 histamine H1 receptor antagonists in two functional modelsOrzechowski RF, et al. European Journal of Pharmacology, 506(3), 257-264 (2005) The antidepressant 5-HT2A receptor antagonists pizotifen and cyproheptadine inhibit serotonin-enhanced platelet functionLin OA, et al. PLoS ONE, 9(1), e87026-e87026 (2014) Development and validation of an ultra-performance liquid chromatography method for simultaneous analysis of 20 antihistaminics in dietary supplements.Jung Yeon Kim et al.Biomedical chromatography : BMC, 29(3), 465-474 (2014-08-01) Anti-inflammatory activity of bartogenic acid containing fraction of fruits of Barringtonia racemosa Roxb. in acute and chronic animal models of inflammationPatil KR and Patil CR Journal of traditional and complementary medicine, 7(1), 86-93 (2017) Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.Jing Yuan et al.Nature chemical biology, 5(10), 765-771 (2009-09-08) Effects of histamine receptor antagonists injected intrathecally on antinociception induced by opioids administered intracerebroventricularly in the mouse.H W Suh et al.Neuropeptides, 33(2), 121-129 (2000-02-05) Developing structure-activity relationships for the prediction of hepatotoxicity.Nigel Greene et al.Chemical research in toxicology, 23(7), 1215-1222 (2010-06-18) Cyproheptadine: a potentially effective treatment for functional gastrointestinal disorders in childrenKrasaelap A and Madani S Pediatric Annals, 46(3), e120-e125 (2017) Identification of cyproheptadine as an inhibitor of SET domain containing lysine methyltransferase 7/9 (Set7/9) that regulates estrogen-dependent transcriptionTakemoto Y, et al. Journal of Medicinal Chemistry, 59(8), 3650-3660 (2016) Overlap in the pharmacology of L-type Ca2+-channel blockers and 5-HT2 receptor antagonists in rat aorta.E O Okoro The Journal of pharmacy and pharmacology, 51(8), 953-957 (1999-09-30) Expression and functional activity of neurotransmitter system components in sea urchins? early developmentNikishin DA, et al. Zygote, 24(2), 206-218 (2016) Chemical genetics reveals a complex functional ground state of neural stem cells.Phedias Diamandis et al.Nature chemical biology, 3(5), 268-273 (2007-04-10) The analgesic agent tapentadol inhibits calcitonin gene-related peptide release from isolated rat brainstem via a serotonergic mechanismGreco MC, et al. Life Sciences, 145, 161-165 (2016) A predictive ligand-based Bayesian model for human drug-induced liver injury.Sean Ekins et al.Drug metabolism and disposition: the biological fate of chemicals, 38(12), 2302-2308 (2010-09-17) Observations on the use of cyproheptadine hydrochloride as an antipruritic agent in allergic cats.Scott DW, et al. The Canadian Veterinary Journal. La Revue Veterinaire Canadienne, 39(10), 634-634 (1998)

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