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3-(2-Chloroquinolin-3-yl)-1-phenylprop-2-en-1-one | CAS:5498-83-9
3-(2-Chloroquinolin-3-yl)-1-phenylprop-2-en-1-one
  • Name:3-(2-Chloroquinolin-3-yl)-1-phenylprop-2-en-1-one
  • CAS:5498-83-9
  • Synonyms:
  • Molecular Formula:C18H12ClNO
  • Molecular Weight:293.74
  • EINESC:

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Expression and modulation of connexin 30.2, a novel gap junction protein in the mouse retina.Luis Pérez de Sevilla Müller et al.Visual neuroscience, 27(3-4), 91-101 (2010-06-12) Design, synthesis and evaluation of mutual prodrug of 4-biphenylacetic acid and quercetin tetramethyl ether (BPA-QTME) as gastrosparing NSAID.Mamta Madhukar et al.European journal of medicinal chemistry, 45(6), 2591-2596 (2010-03-17) Validated LC-MS/MS assay for the determination of felbinac: Application to a preclinical pharmacokinetics study of felbinac trometamol injection in rat.Chao Zhang et al.Journal of pharmaceutical and biomedical analysis, 50(1), 41-45 (2009-04-21) Synthesis and pharmacological evaluation of polyfunctional benzimidazole-NSAID chimeric molecules combining anti-inflammatory, immunomodulatory and antioxidant activities.Yogita Bansal et al.Archives of pharmacal research, 37(11), 1426-1436 (2013-11-06) Synthesis and pharmacological evaluation of some dual-acting amino-alcohol ester derivatives of flurbiprofen and 2-[1,1'-biphenyl-4-yl]acetic acid: a potential approach to reduce local gastrointestinal toxicity.Parmeshwari Kuldeep Kumar Halen et al.Chemistry & biodiversity, 3(11), 1238-1248 (2006-12-29) Quantitative comparison of the convulsive activity of combinations of twelve fluoroquinolones with five nonsteroidal antiinflammatory agents.Jahye Kim et al.Drug metabolism and pharmacokinetics, 24(2), 167-174 (2009-05-12) Some pharmaceutical and inclusion properties of 2-hydroxybutyl-β-cyclodextrin derivative.Takako Ishiguro et al.International journal of pharmaceutics, 419(1-2), 161-169 (2011-08-16) Intercalation and controlled release of pharmaceutically active compounds from a layered double hydroxide.A I Khan et al.Chemical communications (Cambridge, England), (22)(22), 2342-2343 (2002-09-21) Biphenylacetic acid enhances the antagonistic action of fluoroquinolones on the GABA(A)-mediated responses of the isolated guinea-pig ileum.M Koutsoviti-Papadopoulou et al.Pharmacological research, 44(3), 229-233 (2001-09-01) Percutaneous penetration of felbinac after application of transdermal patches: relationship with pharmacological effects in rats.Norihiro Shinkai et al.The Journal of pharmacy and pharmacology, 60(1), 71-76 (2007-12-20) Fluorous derivatization and fluorous-phase separation for fluorometric determination of naproxen and felbinac in human plasma.Yohei Sakaguchi et al.Journal of pharmaceutical and biomedical analysis, 55(1), 176-180 (2011-02-12) Convulsant and subconvulsant doses of norfloxacin in the presence and absence of biphenylacetic acid alter extracellular hippocampal glutamate but not gamma-aminobutyric acid levels in conscious rats.I Smolders et al.Antimicrobial agents and chemotherapy, 46(2), 471-477 (2002-01-18) Enhancing effect of hydroxypropyl-beta-cyclodextrin on cutaneous penetration and activation of ethyl 4-biphenylyl acetate in hairless mouse skin.H Arima et al.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 6(1), 53-59 (2005-11-01) Pharmacokinetics of felbinac after intravenous administration of felbinac trometamol in rats.Chao Zhang et al.Xenobiotica; the fate of foreign compounds in biological systems, 41(4), 340-348 (2010-12-25) Possible intermolecular interaction between quinolones and biphenylacetic acid inhibits gamma-aminobutyric acid receptor sites.K Akahane et al.Antimicrobial agents and chemotherapy, 38(10), 2323-2329 (1994-10-01) Synthesis, characterization and in vitro evaluation of dimethyl-beta-cyclodextrin-4-biphenylylacetic acid conjugate.C A Ventura et al.Journal of drug targeting, 11(4), 233-240 (2003-10-28) Enhancement of 4-biphenylacetic acid bioavailability in rats by its beta-cyclodextrin complex after oral administration.G Puglisi et al.The Journal of pharmacy and pharmacology, 43(6), 430-432 (1991-06-01) Analgesic effect of percutaneously absorbed non-steroidal anti-inflammatory drugs: an experimental study in a rat acute inflammation model.Miho Sekiguchi et al.BMC musculoskeletal disorders, 9, 15-15 (2008-02-01) Mechanisms of drug release in citrate buffered HPMC matrices.Samuel R Pygall et al.International journal of pharmaceutics, 370(1-2), 110-120 (2008-12-23) Effect of enoxacin, felbinac, and sparfloxacin on fatty acid metabolism and glucose concentrations in rat tissues.Fumiyo Kasuya et al.International journal of toxicology, 30(3), 367-376 (2011-06-03) Towards the design of cyclooxygenase (COX) inhibitors based on 4',5 di-substituted biphenyl acetic acid molecules: a QSAR study with a new DFT based descriptor - nucleus independent chemical shift.Ananda Sarkar et al.Journal of molecular modeling, 15(10), 1221-1228 (2009-03-07) Characterization of the interaction between a novel convulsant agent, norbiphen, and GABA(A) and other ligand-gated ion channels.R F Halliwell et al.Neuropharmacology, 43(4), 778-787 (2002-10-09) Discovery and optimization of a biphenylacetic acid series of prostaglandin D2 receptor DP2 antagonists with efficacy in a murine model of allergic rhinitis.Jill M Scott et al.Bioorganic & medicinal chemistry letters, 21(21), 6608-6612 (2011-10-01) The topical NSAID felbinac versus oral NSAIDS: a critical review.G Hosie et al.European journal of rheumatology and inflammation, 14(4), 21-28 (1994-01-01) A novel protocol for the oral administration of test chemicals to adult zebrafish.Liqing Zang et al.Zebrafish, 8(4), 203-210 (2011-12-21) Changes in brain interleukin-1beta following the coadministration of norfloxacin with biphenylacetic acid in rats.Li-rong Zhang et al.European journal of pharmacology, 543(1-3), 21-26 (2006-07-11) Discovery of biphenylacetamide-derived inhibitors of BACE1 using de novo structure-based molecular design.N Yi Mok et al.Journal of medicinal chemistry, 56(5), 1843-1852 (2013-02-05) A pharmacokinetic/pharmacodynamic approach to show that not all fluoroquinolones exhibit similar sensitivity toward the proconvulsant effect of biphenyl acetic acid in rats.S Marchand et al.The Journal of antimicrobial chemotherapy, 48(6), 813-820 (2001-12-26) The suitability of tris(hydroxylmethyl) aminomethane (THAM) as a buffering system for hydroxypropyl methylcellulose (HPMC) hydrophilic matrices containing a weak acid drug.Samuel R Pygall et al.International journal of pharmaceutics, 387(1-2), 93-102 (2009-12-17) Monitoring the concentrations of nonsteroidal anti-inflammatory drugs and cyclooxygenase-inhibiting activities in the surface waters of the Tone Canal and Edo River Basin.Iwaki Nishi et al.Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 50(11), 1108-1115 (2015-07-21)
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