没有数据	没有数据

Symbol(GHS)	T;N
Hazard Codes	R20/21/22;R50/53
SDS/MSDS	S36/37;S60;S61

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Relaxant effect of adrenomedullin on bovine isolated iris sphincter muscle under resting conditions.Y Uchikawa et al.Clinical and experimental pharmacology & physiology, 32(8), 675-680 (2005-08-27) Antihypertensive effects of allicin on spontaneously hypertensive rats via vasorelaxation and hydrogen sulfide mechanisms.Tianwei Cui et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 128, 110240-110240 (2020-06-02) Structural and signaling requirements of the human melanocortin 4 receptor for MAP kinase activation.Caroline S Patten et al.Regulatory peptides, 142(3), 111-122 (2007-03-23) Signaling pathways for modulation of mouse sperm motility by adenosine and catecholamine agonists.Sonya M Schuh et al.Biology of reproduction, 74(3), 492-500 (2005-11-18) Lipolysis is stimulated by PEGylated conjugated linoleic acid through the cyclic adenosine monophosphate-independent signaling pathway in 3T3-L1 cells: activation of MEK/ERK MAPK signaling pathway and hyper-secretion of adipo-cytokines.Hyun-Seuk Moon et al.Journal of cellular physiology, 214(2), 283-294 (2007-07-27) Homotypic gap junctional communication associated with metastasis suppression increases with PKA activity and is unaffected by PI3K inhibition.Thomas M Bodenstine et al.Cancer research, 70(23), 10002-10011 (2010-11-26) Decreased adenylyl cyclase and cAMP-dependent protein kinase activities inhibit the cytotoxic function of human natural killer cells.Amanuel K Bariagaber et al.Human immunology, 64(9), 866-873 (2003-08-28) Impaired complement-mediated phagocytosis by HIV type-1-infected human monocyte-derived macrophages involves a cAMP-dependent mechanism.Rula Azzam et al.AIDS research and human retroviruses, 22(7), 619-629 (2006-07-13) Adenylate cyclase 5 and KCa1.1 channel are required for EGFR up-regulation of PCNA in native contractile rat basilar artery smooth muscle.Alexander Ivanov et al.The Journal of physiology, 570(Pt 1), 73-84 (2005-11-15) Multiple pathways from three types of sugar receptor sites to metabotropic transduction pathways of the blowfly: study by the whole cell-clamp experiments.Hideko Kan et al.Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 160(1), 94-99 (2011-06-01) Role of regulator of G-protein signaling 2 (RGS2) in periodontal ligament cells under mechanical stress.Rui M Santos de Araujo et al.Cell biochemistry and function, 25(6), 753-758 (2007-02-13) Nicotine and epibatidine triggered prolonged rise in calcium and TH gene transcription in PC12 cells.Volodia D Gueorguiev et al.European journal of pharmacology, 506(1), 37-46 (2004-12-14) Adenylyl Cyclases.Johnson, R.A. et al.Encyclopedic Reference of Molecular Pharmacology (2003) Glucagon-like peptide-1 protects mesenteric endothelium from injury during inflammation.Kristopher C Dozier et al.Peptides, 30(9), 1735-1741 (2009-06-30) Sustained β-AR stimulation induces synthesis and secretion of growth factors in cardiac myocytes that affect on cardiac fibroblast activation.Narawat Nuamnaichati et al.Life sciences, 193, 257-269 (2017-11-07) Stimulation of the cAMP system by the nitric oxide-cGMP system underlying the formation of long-term memory in an insect.Yukihisa Matsumoto et al.Neuroscience letters, 467(2), 81-85 (2009-10-13) Multiple signalling pathways involved in beta2-adrenoceptor-mediated glucose uptake in rat skeletal muscle cells.Julia Nevzorova et al.British journal of pharmacology, 147(4), 446-454 (2006-01-18) ONO-1301 loaded nanocomposite scaffolds modulate cAMP mediated signaling and induce new bone formation in critical sized bone defect.Shruthy Kuttappan et al.Biomaterials science, 8(3), 884-896 (2019-12-12) Tramadol-induced block of hyperpolarization-activated cation current in rat pituitary lactotrophs.Yen-Chin Liu et al.Naunyn-Schmiedeberg's archives of pharmacology, 379(2), 127-135 (2008-09-27) Roles of NO signaling in long-term memory formation in visual learning in an insect.Yukihisa Matsumoto et al.PloS one, 8(7), e68538-e68538 (2013-07-31) Gastroprotective effect of diligustilide isolated from roots of Ligusticum porteri coulter & rose (Apiaceae) on ethanol-induced lesions in ratsVelazquez-Moyado J, et al. Journal of Ethnopharmacology, 174, 403-409 (2015) Involvement of cAMP in nerve growth factor-triggered p35/Cdk5 activation and differentiation in PC12 cells.Mei-Chih Chen et al.American journal of physiology. Cell physiology, 299(2), C516-C527 (2010-05-14) Molecular signaling underlying bulleyaconitine A (BAA)-induced microglial expression of prodynorphin.Teng-Fei Li et al.Scientific reports, 7, 45056-45056 (2017-03-23) Phosphoramidate derivatives of 2',5'-dideoxyadenosine as potential inhibitors of the EDHF phenomenon.F Gavazza et al.Nucleosides, nucleotides & nucleic acids, 24(5-7), 553-555 (2005-10-27) Adenylyl cyclase P-site ligands accelerate differentiation in Ob1771 preadipocytes.A Ibrahimi et al.The American journal of physiology, 276(2 Pt 1), C487-C496 (1999-02-10) Evidence for multiple distinctly localized adenylyl cyclase isoforms in mammalian spermatozoa.Rhona W Baxendale et al.Molecular reproduction and development, 66(2), 181-189 (2003-09-02) Elevated cyclic AMP levels promote BRAFCA/Pten-/- mouse melanoma growth but pCREB is negatively correlated with human melanoma progressionRodriguez CI, et al. Cancer letters, 414, 268-277 (2018) Prostaglandin E(2) protects human lung fibroblasts from cigarette smoke extract-induced apoptosis via EP(2) receptor activation.Hisatoshi Sugiura et al.Journal of cellular physiology, 210(1), 99-110 (2006-09-26) Adenosine causes read-through into the late region of the HPV16 genome in a guanosine-dependent manner.Haoran Yu et al.Virology, 521, 1-19 (2018-06-05) Cyclic AMP signaling contributes to neural plasticity and hyperexcitability in AH sensory neurons following intestinal Trichinella spiralis-induced inflammation.Zhixiong Chen et al.International journal for parasitology, 37(7), 743-761 (2007-02-20) Relaxation of isolated guinea-pig trachea by apigenin, a constituent of celery, via inhibition of phosphodiesterase.Junn-Lain Chen et al.European journal of pharmacology, 811, 129-133 (2017-06-13) Multiple molecular pathways stimulating macroautophagy protect from alpha-synuclein-induced toxicity in human neurons.Matthias Höllerhage et al.Neuropharmacology, 149, 13-26 (2019-02-08) A new site and mechanism of action for the widely used adenylate cyclase inhibitor SQ22,536.Andrew C Emery et al.Molecular pharmacology, 83(1), 95-105 (2012-10-12) Regulatory T Cells Contribute to HIV-1 Reservoir Persistence in CD4+ T Cells Through Cyclic Adenosine Monophosphate-Dependent Mechanisms in Humanized Mice In Vivo.Guangming Li et al.The Journal of infectious diseases, 216(12), 1579-1591 (2017-10-19) Cyclooxygenase-2 induction by bradykinin in aortic vascular smooth muscle cells.Jorge A Rodriguez et al.American journal of physiology. Heart and circulatory physiology, 290(1), H30-H36 (2005-09-07) Identification of 17,20β,21-trihydroxy-4-pregnen-3-one (20β-S) receptor binding and membrane progestin receptor alpha on southern flounder sperm (Paralichthys lethostigma) and their likely role in 20β-S stimulation of sperm hypermotility.Christopher Tubbs et al.General and comparative endocrinology, 170(3), 629-639 (2010-12-18) Synthesis and use of 3'-(azidoiodosalicyl) derivatives of 2', 5'-dideoxyadenosine as photoaffinity ligands for adenylyl cyclase.I Shoshani et al.Archives of biochemistry and biophysics, 376(1), 221-228 (2000-03-24) Regulation of MMP-3 expression and secretion by the chemokine eotaxin-1 in human chondrocytes.Pin-Zhir Chao et al.Journal of biomedical science, 18, 86-86 (2011-11-26) cAMP-dependent cell differentiation triggered by activated CRHR1 in hippocampal neuronal cells.Carolina Inda et al.Scientific reports, 7(1), 1944-1944 (2017-05-18) Effect of cyclic AMP on barrier function of human lymphatic microvascular tubes.Gavrielle M Price et al.Microvascular research, 76(1), 46-51 (2008-04-29) Salbutamol inhibits trypsin-mediated production of CXCL8 by keratinocytes.Frank R Wettey et al.Cytokine, 36(1-2), 29-34 (2006-12-13) Phosphorylation of paracellin-1 at Ser217 by protein kinase A is essential for localization in tight junctions.Akira Ikari et al.Journal of cell science, 119(Pt 9), 1781-1789 (2006-04-13) Adiponectin suppresses IkappaB kinase activation induced by tumor necrosis factor-alpha or high glucose in endothelial cells: role of cAMP and AMP kinase signaling.Xiangdong Wu et al.American journal of physiology. Endocrinology and metabolism, 293(6), E1836-E1844 (2007-10-18)

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