Melting point	-18 ºC
Water Solubility	0.2 g/100 mL (25 ºC)
Boiling point	172-173 ºC
Flash point	55 ºC
Density	1.06
Refractive index	1.538-1.54

Symbol(GHS)	Xn
Hazard Codes	R10;R22
SDS/MSDS	S16;S23;S26;S36/37/39

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Essential oil constituents of Eclipta prostrata (L.) L. and Vernonia amygdalina Delile.Akinola O Ogunbinu et al.Natural product communications, 4(3), 421-424 (2009-05-06) Novel norhumulene and xeniaphyllane-derived terpenoids from a formosan soft coral Sinularia gibberosa.Shin-Pin Chen et al.Chemical & pharmaceutical bulletin, 57(2), 162-166 (2009-02-03) Altered cross-linking of HSP27 by zerumbone as a novel strategy for overcoming HSP27-mediated radioresistance.Seo-Hyun Choi et al.International journal of radiation oncology, biology, physics, 79(4), 1196-1205 (2011-03-01) Solid-phase micro-extraction (SPME) in the early detection of potentially active volatile compounds from organic wastes used for the management of soil-borne pathogens.Esther De La Fuente et al.Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 44(10), 1004-1010 (2009-10-16) [Analysis of the chemical constituents of essential oil from the leaves of Callicarpa integerrima].Ling Chai et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 33(3), 382-385 (2010-08-05) Secondary organic aerosol formation from the oxidation of a series of sesquiterpenes: α-cedrene, β-caryophyllene, α-humulene and α-farnesene with O3, OH and NO3 radicalsJaoui M, et al. Environmental Chemistry, 10(3), 178-193 (2013) In vitro cytotoxic effects of Senecio stabianus Lacaita (Asteraceae) on human cancer cell lines.Rosa Tundis et al.Natural product research, 23(18), 1707-1718 (2009-11-19) Transient expression and purification of β-caryophyllene synthase in Nicotiana benthamiana to produce β-caryophyllene in vitro.Saraladevi Muthusamy et al.PeerJ, 8, e8904-e8904 (2020-05-08) Potentiating effect of beta-caryophyllene on anticancer activity of alpha-humulene, isocaryophyllene and paclitaxel.Jean Legault et al.The Journal of pharmacy and pharmacology, 59(12), 1643-1647 (2007-12-07) Analysis of the essential oil of Amsonia illustris.Annamaria London et al.Natural product communications, 6(2), 235-236 (2011-03-24) Isolation and biomimetic synthesis of (±)-guajadial B, a novel meroterpenoid from Psidium guajava.Yuan Gao et al.Organic letters, 14(23), 5936-5939 (2012-11-21) Preventive and therapeutic anti-inflammatory properties of the sesquiterpene alpha-humulene in experimental airways allergic inflammation.Alexandre P Rogerio et al.British journal of pharmacology, 158(4), 1074-1087 (2009-05-15) Pharmacokinetics and tissue distribution of the sesquiterpene alpha-humulene in mice.Juliana Siqueira Chaves et al.Planta medica, 74(14), 1678-1683 (2008-10-28) An investigation on the chemotactic responses of different entomopathogenic nematode strains to mechanically damaged maize root volatile compounds.Z Laznik et al.Experimental parasitology, 134(3), 349-355 (2013-04-09) [Extraction and identification of volatile constituents in the flowers of Aglaia odorata Lour].Junsong Zhang et al.Se pu = Chinese journal of chromatography, 25(3), 422-424 (2007-08-08) The gas-phase ozonolysis of α-humulene.M Beck et al.Physical chemistry chemical physics : PCCP, 13(23), 10970-11001 (2011-04-05) Validation of a gas chromatographic method to quantify sesquiterpenes in copaiba oils.João Paulo B Sousa et al.Journal of pharmaceutical and biomedical analysis, 54(4), 653-659 (2010-11-26) Reaction mechanism of direct episulfidation of caryophyllene and humulene.Tatsuya Ashitani et al.Natural product research, 22(6), 495-498 (2008-04-17) Origin of regioselectivity in α-humulene functionalization.Ulrich Neuenschwander et al.The Journal of organic chemistry, 77(6), 2865-2869 (2012-02-16) Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency.Jian-Xu Li et al.The Biochemical journal, 451(3), 417-426 (2013-02-27) Anti-inflammatory effects of compounds alpha-humulene and (-)-trans-caryophyllene isolated from the essential oil of Cordia verbenacea.Elizabeth S Fernandes et al.European journal of pharmacology, 569(3), 228-236 (2007-06-15) Efficient synthesis of functional isoprenoids from acetoacetate through metabolic pathway-engineered Escherichia coli.Hisashi Harada et al.Applied microbiology and biotechnology, 81(5), 915-925 (2008-10-07) [Study on the volatile oil of Murraya exotica].Ping-Chuan Jiang et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 32(8), 1224-1227 (2009-12-08) Molecular cloning and functional characterization of alpha-humulene synthase, a possible key enzyme of zerumbone biosynthesis in shampoo ginger (Zingiber zerumbet Smith).Fengnian Yu et al.Planta, 227(6), 1291-1299 (2008-02-15) Death receptor 5-mediated TNFR family signaling pathways modulate γ-humulene-induced apoptosis in human colorectal cancer HT29 cells.Yu-Hsuan Lan et al.Oncology reports, 25(2), 419-424 (2010-12-15) Zingiber zerumbet CYP71BA1 catalyzes the conversion of α-humulene to 8-hydroxy-α-humulene in zerumbone biosynthesis.Fengnian Yu et al.Cellular and molecular life sciences : CMLS, 68(6), 1033-1040 (2010-08-24) Sterhirsutins A and B, two new heterodimeric sesquiterpenes with a new skeleton from the culture of Stereum hirsutum collected in Tibet Plateau.Qiu-Yue Qi et al.Organic letters, 16(19), 5092-5095 (2014-09-13) Antiulcerogenic and anti-inflammatory activities of the essential oil from Pterodon emarginatus seeds.Rafael C Dutra et al.The Journal of pharmacy and pharmacology, 61(2), 243-250 (2009-01-31)

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