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Synthetic Route

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Articles

Peer-Reviewed Papers

Fungal metabolites of xanthohumol with potent antiproliferative activity on human cancer cell lines in vitro.Tomasz Tronina et al.Bioorganic & medicinal chemistry, 21(7), 2001-2006 (2013-02-26) Broad spectrum anti-infective potential of xanthohumol from hop (Humulus lupulus L.) in comparison with activities of other hop constituents and xanthohumol metabolites.Clarissa Gerhäuser Molecular nutrition & food research, 49(9), 827-831 (2005-08-11) Xanthohumol and related prenylflavonoids from hops and beer: to your good health!Jan F Stevens et al.Phytochemistry, 65(10), 1317-1330 (2004-07-03) Pitfalls in cell culture work with xanthohumol.M Motyl et al.Die Pharmazie, 67(1), 91-94 (2012-03-08) The AKT/NF-κB inhibitor xanthohumol is a potent anti-lymphocytic leukemia drug overcoming chemoresistance and cell infiltration.Roberto Benelli et al.Biochemical pharmacology, 83(12), 1634-1642 (2012-03-27) Xanthohumol suppresses inflammatory response to warm ischemia-reperfusion induced liver injury.Christoph Dorn et al.Experimental and molecular pathology, 94(1), 10-16 (2012-05-29) Protective effect of xanthohumol on toxin-induced liver inflammation and fibrosis.Christoph Dorn et al.International journal of clinical and experimental pathology, 5(1), 29-36 (2012-02-02) Xanthohumol induces different cytotoxicity and apoptotic pathways in malignant and normal astrocytes.I Zajc et al.Phytotherapy research : PTR, 26(11), 1709-1713 (2012-03-13) Investigation of the anxiolytic effects of xanthohumol, a component of humulus lupulus (Hops), in the male Sprague-Dawley rat.Thomas E Ceremuga et al.AANA journal, 81(3), 193-198 (2013-08-09) Salmonella enterica serovar Oranienburg outbreak in a veterinary medical teaching hospital with evidence of nosocomial and on-farm transmission.Kevin J Cummings et al.Vector borne and zoonotic diseases (Larchmont, N.Y.), 14(7), 496-502 (2014-06-06) Xanthohumol prevents carbon tetrachloride-induced acute liver injury in rats.Carmen Pinto et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(10), 3405-3412 (2012-08-14) 2-Hydroxychalcone and xanthohumol inhibit invasion of triple negative breast cancer cells.Sun Young Kim et al.Chemico-biological interactions, 203(3), 565-572 (2013-04-09) Xanthohumol modulates inflammation, oxidative stress, and angiogenesis in type 1 diabetic rat skin wound healing.Raquel Costa et al.Journal of natural products, 76(11), 2047-2053 (2013-11-10) K-targeted metabolomic analysis extends chemical subtraction to DESIGNER extracts: selective depletion of extracts of hops (Humulus lupulus).René F Ramos Alvarenga et al.Journal of natural products, 77(12), 2595-2604 (2014-12-02) Inverse Virtual Screening allows the discovery of the biological activity of natural compounds.Gianluigi Lauro et al.Bioorganic & medicinal chemistry, 20(11), 3596-3602 (2012-04-28) Xanthohumol induces phase II enzymes via Nrf2 in human hepatocytes in vitro.Violetta Krajka-Kuźniak et al.Toxicology in vitro : an international journal published in association with BIBRA, 27(1), 149-156 (2012-10-23) Xanthohumol impairs human prostate cancer cell growth and invasion and diminishes the incidence and progression of advanced tumors in TRAMP mice.Roberta Venè et al.Molecular medicine (Cambridge, Mass.), 18, 1292-1302 (2012-09-07) Protective effects of arachidonic acid against palmitic acid-mediated lipotoxicity in HIT-T15 cells.Young Sik Cho et al.Molecular and cellular biochemistry, 364(1-2), 19-28 (2011-12-29) Modification of the cysteine residues in IkappaBalpha kinase and NF-kappaB (p65) by xanthohumol leads to suppression of NF-kappaB-regulated gene products and potentiation of apoptosis in leukemia cells.Kuzhuvelil B Harikumar et al.Blood, 113(9), 2003-2013 (2008-10-28) Neuroprotective effects of xanthohumol, a prenylated flavonoid from hops (Humulus lupulus), in ischemic stroke of rats.Ting-Lin Yen et al.Journal of agricultural and food chemistry, 60(8), 1937-1944 (2012-02-04) Preliminary in vitro study on the effect of xanthohumol on rumen methanogenesis.Pawel Zmora et al.Archives of animal nutrition, 66(1), 66-71 (2012-03-09) Anticancer agent xanthohumol inhibits IL-2 induced signaling pathways involved in T cell proliferation.Yongbo Liu et al.Journal of experimental therapeutics & oncology, 10(1), 1-8 (2012-09-06) Xanthohumol impairs autophagosome maturation through direct inhibition of valosin-containing protein.Yukiko Sasazawa et al.ACS chemical biology, 7(5), 892-900 (2012-03-01) The radio-sensitizing effect of xanthohumol is mediated by STAT3 and EGFR suppression in doxorubicin-resistant MCF-7 human breast cancer cells.Youra Kang et al.Biochimica et biophysica acta, 1830(3), 2638-2648 (2012-12-19) Prenylated chalcone xanthohumol associates with histones in breast cancer cells--a novel target identified by a monoclonal antibody.Ciska Wyns et al.Molecular nutrition & food research, 56(11), 1688-1696 (2012-09-25) Search method for inhibitors of Staphyloxanthin production by methicillin-resistant Staphylococcus aureus.Kent Sakai et al.Biological & pharmaceutical bulletin, 35(1), 48-53 (2012-01-10) Regulation of intracellular pH by glycosaminoglycans.Nadine Kathagen et al.Journal of cellular physiology, 228(10), 2071-2075 (2013-04-06) Interaction of prenylated chalcones and flavanones from common hop with phosphatidylcholine model membranes.Olga Wesołowska et al.Biochimica et biophysica acta, 1838(1 Pt B), 173-184 (2013-09-26) Fundamentals and health benefits of xanthohumol, a natural product derived from hops and beer.Paulo J Magalhães et al.Natural product communications, 4(5), 591-610 (2009-05-19) Xanthohumol prevents atherosclerosis by reducing arterial cholesterol content via CETP and apolipoprotein E in CETP-transgenic mice.Hiroshi Hirata et al.PloS one, 7(11), e49415-e49415 (2012-11-21) Xanthohumol inhibits growth and vascularization of developing endometriotic lesions.J Rudzitis-Auth et al.Human reproduction (Oxford, England), 27(6), 1735-1744 (2012-03-27) Geranyl derivative of phloroacetophenone induces cancer cell-specific apoptosis through Bax-mediated mitochondrial pathway in MCF-7 human breast cancer cells.Mi-Yeon Cho et al.Biological & pharmaceutical bulletin, 35(1), 98-104 (2012-01-10) A metabolomics-driven elucidation of the anti-obesity mechanisms of xanthohumol.Jay S Kirkwood et al.The Journal of biological chemistry, 288(26), 19000-19013 (2013-05-16) The molecular organization of prenylated flavonoid xanthohumol in DPPC multibilayers: X-ray diffraction and FTIR spectroscopic studies.Marta Arczewska et al.Biochimica et biophysica acta, 1828(2), 213-222 (2012-10-23)

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