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2,6-Dihydroxybenzoic acid | CAS:303-07-1
2,6-Dihydroxybenzoic acid
  • Name:2,6-Dihydroxybenzoic acid
  • CAS:303-07-1
  • Synonyms:2,6-Resorcylic acid; gamma-Resorcylic acid
  • Molecular Formula:C7H6O4
  • Molecular Weight:154.12
  • EINESC:206-134-8

Description

Properties

Melting point 154-155 ºC

Safety

Symbol(GHS) Xi
Hazard Codes R36/37/38
SDS/MSDS S26;S36

SDS

Source SDS/MSDS Samples
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Synthetic Route
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Articles
Peer-Reviewed Papers
Reaction with 4-(p-nitrobenzyl)pyridine allows detection of urethane-protected pyroglutamyl residues.H Süli-Vargha et al.Peptide research, 7(1), 24-26 (1994-01-01) Clinical pharmacokinetics of cyclophosphamide and metabolites with and without SR-2508.K K Chan et al.Cancer research, 54(24), 6421-6429 (1994-12-15) Biologically stable [(18)F]-labeled benzylfluoride derivatives.Y Magata et al.Nuclear medicine and biology, 27(2), 163-168 (2000-04-25) Colorimetric assays for quantitative analysis and screening of epoxide hydrolase activity.F Cedrone et al.Biotechnology letters, 27(23-24), 1921-1927 (2005-12-06) The relationship between reactivity of metabolites of pyrrolizidine alkaloids and extrahepatic toxicity.R A Cooper et al.Proceedings of the Western Pharmacology Society, 42, 13-16 (2000-03-04) Chemoassay screening of DNA-reactive mutagenicity with 4-(4-nitrobenzyl)pyridine - application to epoxides, oxetanes, and sulfur heterocycles.Diana Thaens et al.Chemical research in toxicology, 25(10), 2092-2102 (2012-08-15) 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one (DIMBOA) inhibits trichothecene production by Fusarium graminearum through suppression of Tri6 expression.Thomas Etzerodt et al.International journal of food microbiology, 214, 123-128 (2015-08-16) Mutagenicity of bisphenol A (4,4'-isopropylidenediphenol) in vitro: effects of nitrosylation.Timothy J Schrader et al.Teratogenesis, carcinogenesis, and mutagenesis, 22(6), 425-441 (2002-10-24) Colorimetric Detection of Carcinogenic Alkylating Fumigants on a Nylon 6 Nanofibrous Membrane. Part II: Self-Catalysis of 2-Diethylaminoethyl-Modified Sensor Matrix for Improvement of Sensitivity.Peixin Tang et al.ACS applied materials & interfaces, 11(14), 13632-13641 (2019-03-21) Sorbate-nitrite interactions: acetonitrile oxide as an alkylating agent.M Teresa Pérez-Prior et al.Chemical research in toxicology, 22(7), 1320-1324 (2009-07-08) Spectroscopic aqueous-phase assay for alkylating activity suitable for automation or multiwell plate application.P G Penketh et al.Analytical biochemistry, 231(2), 452-455 (1995-11-01) Direct colorimetric method for determination of organophosphates in human urine.A Namera et al.Clinica chimica acta; international journal of clinical chemistry, 291(1), 9-18 (1999-12-29) Chemical reactivity and biological activity of diketene.Rafael Gómez-Bombarelli et al.Chemical research in toxicology, 21(10), 1964-1969 (2008-09-02) Gas-phase ion-molecule reactions: a model for the determination of biologically reactive electrophilic contaminants in the environment.J A Freeman et al.Analytical chemistry, 66(11), 1902-1910 (1994-06-01) Studies on the mechanism of decomposition and structural factors affecting the aqueous stability of 1,2-bis(sulfonyl)-1-alkylhydrazines.P G Penketh et al.Journal of medicinal chemistry, 37(18), 2912-2917 (1994-09-02) DNA-damaging disinfection byproducts: alkylation mechanism of mutagenic mucohalic acids.Rafael Gómez-Bombarelli et al.Environmental science & technology, 45(20), 9009-9016 (2011-09-14) In vitro induction of micronuclei by monofunctional methanesulphonic acid esters: possible role of alkylation mechanisms.Erwin Eder et al.Chemico-biological interactions, 164(1-2), 76-84 (2006-10-03) Abietane diterpenes induce cytotoxic effects in human pancreatic cancer cell line MIA PaCa-2 through different modes of action.Marcio Fronza et al.Phytochemistry, 78, 107-119 (2012-03-23) In vitro alkylating of alpha, beta-unsaturated amidoesters, diethyl pyridylmethylphosphonates and their cis-Pt(II)complexes.L Najman-Bronzewska et al.Die Pharmazie, 52(3), 198-202 (1997-03-01) Potential of the NBP method for the study of alkylation mechanisms: NBP as a DNA-model.Rafael Gómez-Bombarelli et al.Chemical research in toxicology, 25(6), 1176-1191 (2012-04-07) Use of 4-(nitrobenzyl)pyridine (4-NBP) to test mutagenic potential of slow-reacting epoxides, their corresponding olefins, and other alkylating agents.J H Kim et al.Bulletin of environmental contamination and toxicology, 49(6), 879-885 (1992-12-01) A spectrophotometric method for determination of phosgene in air.S K Dangwal Industrial health, 32(1), 41-47 (1994-01-01) The determination of busulphan in dissolution samples by flow injection analysis.A D Dow et al.Journal of pharmaceutical and biomedical analysis, 19(3-4), 549-554 (2000-03-07) Reaction kinetics of alkyl epoxides with DNA and other nucleophiles.A Hemminki et al.Chemico-biological interactions, 93(1), 51-58 (1994-10-01) On-resin real-time reaction monitoring of solid-phase oligosaccharide synthesis.Shino Manabe et al.Journal of the American Chemical Society, 124(43), 12638-12639 (2002-10-24) Structures of cytochrome P450 2B6 bound to 4-benzylpyridine and 4-(4-nitrobenzyl)pyridine: insight into inhibitor binding and rearrangement of active site side chains.Manish B Shah et al.Molecular pharmacology, 80(6), 1047-1055 (2011-08-31) Connecting the chemical and biological reactivity of epoxides.Marina González-Pérez et al.Chemical research in toxicology, 25(12), 2755-2762 (2012-11-23) Application of high-performance thin-layer chromatography for the detection of organophosphorus insecticides in human serum after acute poisoning.K Futagami et al.Journal of chromatography. B, Biomedical sciences and applications, 704(1-2), 369-373 (1998-03-28) Reductive activation of mitomycin C by neuronal nitric oxide synthase.H B Jiang et al.Biochemical pharmacology, 60(4), 571-579 (2000-06-30)
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