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4'-Chloro-2,2,2-trifluoroacetophenone | CAS:321-37-9
4'-Chloro-2,2,2-trifluoroacetophenone
  • Name:4'-Chloro-2,2,2-trifluoroacetophenone
  • CAS:321-37-9
  • Synonyms:1-(4-Chlorophenyl)-2,2,2-trifluoroethanone; 1-(4-Chlorophenyl)-2,2,2-trifluoroethan-1-one
  • Molecular Formula:C8H4ClF3O
  • Molecular Weight:208.56
  • EINESC:

Description

Properties

Melting point 24-26 ºC
Boiling point 180-183 ºC
Flash point 78 ºC
Density 1.398
Refractive index 1.489

Safety

Symbol(GHS) Xi
Hazard Codes R36/37/38
SDS/MSDS S26

SDS

Source SDS/MSDS Samples
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Synthetic Route
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Articles
Peer-Reviewed Papers
Carcinogenicity and mutagenicity of 4-nitropyridine 1-oxide derivatives.K Takahashi et al.Gan, 70(6), 799-806 (1979-12-01) Chemopreventive effect of fermented brown rice and rice bran on 4-nitroquinoline 1-oxide-induced oral carcinogenesis in rats.Nguyen Khanh Long et al.Oncology reports, 17(4), 879-885 (2007-03-08) The Primary Photochemical Process of 4-Nitropyridine N-Oxide. Hata N, et al. Bulletin of the Chemical Society of Japan, 41(8), 1769-1775 (1968) Reactivity of 4-nitropyridine-N-oxide: Preparation of 4-substituted derivatives of pyridine-N-oxide and pyridine. Den Hertog HJ and Combe WP. Rec. Trav. Chim., 70(7), 581-590 (1951) Well-known quorum sensing inhibitors do not affect bacterial quorum sensing-regulated bean sprout spoilage.M Rasch et al.Journal of applied microbiology, 102(3), 826-837 (2007-02-21) A characterization study on 2,6-dimethyl-4-nitropyridine N-oxide by density functional theory calculations.G Yildirim et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 81(1), 104-110 (2011-07-05) Nitroreductase activity of heart lipoamide dehydrogenase.C S Tsai The Biochemical journal, 242(2), 447-452 (1987-03-01) From Physical Mixtures to Co-Crystals: How the Coformers Can Modify Solubility and Biological Activity of Carbamazepine.Alessandro Dalpiaz et al.Molecular pharmaceutics, 15(1), 268-278 (2017-11-23) Pseudomonas aeruginosa Biofilm Formation and Persistence, along with the Production of Quorum Sensing-Dependent Virulence Factors, Are Disrupted by a Triterpenoid Coumarate Ester Isolated from Dalbergia trichocarpa, a Tropical Legume.Tsiry Rasamiravaka et al.PloS one, 10(7), e0132791-e0132791 (2015-07-18) DNA double-strand break repair in parental chromatin of mouse zygotes, the first cell cycle as an origin of de novo mutation.Alwin Derijck et al.Human molecular genetics, 17(13), 1922-1937 (2008-03-21) At a supra-physiological concentration, human sexual hormones act as quorum-sensing inhibitors.Amélie Beury-Cirou et al.PloS one, 8(12), e83564-e83564 (2014-01-01) On the structure of 4-nitropyridine-N-oxide. Eichhorn EL. Acta Crystallographica, 9(10), 787-793 (1956) Nitroarene reduction and generation of free radicals by cell-free extracts of wild-type, and nitroreductase-deficient and -enriched Salmonella typhimurium strains used in the umu gene induction assay.C A Metosh-Dickey et al.Toxicology and applied pharmacology, 154(2), 126-134 (1999-02-02) Reduced bacterial deposition and attachment by quorum-sensing inhibitor 4-nitro-pyridine-N-oxide: the role of physicochemical effects.Nune Vanoyan et al.Langmuir : the ACS journal of surfaces and colloids, 26(14), 12089-12094 (2010-06-18) Facile one-pot direct arylation and alkylation of nitropyridine N-oxides with Grignard reagents.Fang Zhang et al.Organic letters, 13(22), 6102-6105 (2011-10-29)
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