Boiling point	253-255 ºC**
Flash point	98.0±27.3 ºC, 计算值*
Density	1.417±0.06 g/cm3 (20 º

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Source	SDS/MSDS Samples
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Synthetic Route

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Articles

Peer-Reviewed Papers

Triterpenoid pristimerin synergizes with taxol to induce cervical cancer cell death through reactive oxygen species-mediated mitochondrial dysfunction.Da-Young Eum et al.Anti-cancer drugs, 22(8), 763-773 (2011-06-07) Antiproliferative activity of pristimerin isolated from Maytenus ilicifolia (Celastraceae) in human HL-60 cells.Patricia Marçal da Costa et al.Toxicology in vitro : an international journal published in association with BIBRA, 22(4), 854-863 (2008-02-26) Antimitotic quinoid triterpenes from Maytenus chuchuhuasca.Hiroshi Morita et al.Bioorganic & medicinal chemistry letters, 18(3), 1050-1052 (2008-01-01) Identification of a potent natural triterpenoid inhibitor of proteosome chymotrypsin-like activity and NF-kappaB with antimyeloma activity in vitro and in vivo.Rodger E Tiedemann et al.Blood, 113(17), 4027-4037 (2008-12-20) Pristimerin induces apoptosis in imatinib-resistant chronic myelogenous leukemia cells harboring T315I mutation by blocking NF-kappaB signaling and depleting Bcr-Abl.Zhongzheng Lu et al.Molecular cancer, 9, 112-112 (2010-05-21) Biomimetic synthesis of xuxuarines Ealpha and Ebeta: structure revision of Rzedowskia bistriterpenoids.Neil E Jacobsen et al.Bioorganic & medicinal chemistry, 16(4), 1884-1889 (2007-12-07) Pristimerin, a naturally occurring triterpenoid, protects against autoimmune arthritis by modulating the cellular and soluble immune mediators of inflammation and tissue damage.Li Tong et al.Clinical immunology (Orlando, Fla.), 155(2), 220-230 (2014-10-14) Pristimerin induces apoptosis by targeting the proteasome in prostate cancer cells.Huanjie Yang et al.Journal of cellular biochemistry, 103(1), 234-244 (2007-06-02) Pristimerin Exacerbates Cellular Injury in Conditionally Reprogrammed Patient-Derived Lung Adenocarcinoma Cells by Aggravating Mitochondrial Impairment and Endoplasmic Reticulum Stress through EphB4/CDC42/N-WASP Signaling.Yubo Tang et al.Oxidative medicine and cellular longevity, 2020, 7409853-7409853 (2020-08-01) Pristimerin induces caspase-dependent apoptosis in MDA-MB-231 cells via direct effects on mitochondria.Chin-Chung Wu et al.Molecular cancer therapeutics, 4(8), 1277-1285 (2005-08-12) Anticytomegalovirus activity of pristimerin, a triterpenoid quinone methide isolated from Maytenus heterophylla (Eckl. & Zeyh.).Tsugiya Murayama et al.Antiviral chemistry & chemotherapy, 18(3), 133-139 (2007-07-14) Pristimerin, a triterpenoid, inhibits tumor angiogenesis by targeting VEGFR2 activation.Xianmin Mu et al.Molecules (Basel, Switzerland), 17(6), 6854-6868 (2012-06-07) Reactive oxygen species-dependent activation of Bax and poly(ADP-ribose) polymerase-1 is required for mitochondrial cell death induced by triterpenoid pristimerin in human cervical cancer cells.Joo-Yun Byun et al.Molecular pharmacology, 76(4), 734-744 (2009-07-04) The triterpenoid quinonemethide pristimerin inhibits induction of inducible nitric oxide synthase in murine macrophages.V M Dirsch et al.European journal of pharmacology, 336(2-3), 211-217 (1998-01-24) Antifungal properties of pristimerin and celastrol isolated from Celastrus hypoleucus.Du-Qiang Luo et al.Pest management science, 61(1), 85-90 (2004-12-14) Targeting tumor proteasome with traditional Chinese medicine.Huanjie Yang et al.Current drug discovery technologies, 7(1), 46-53 (2010-02-17) Pristimerin inhibits breast cancer cell migration by up- regulating regulator of G protein signaling 4 expression.Xian-Min Mu et al.Asian Pacific journal of cancer prevention : APJCP, 13(4), 1097-1104 (2012-07-18) Pristimerin causes G1 arrest, induces apoptosis, and enhances the chemosensitivity to gemcitabine in pancreatic cancer cells.Yongwei Wang et al.PloS one, 7(8), e43826-e43826 (2012-09-07) [In vitro activity of the pristinamycin against the isolated staphylococci in the french hospitals in 1999-2000].R Leclercq et al.Pathologie-biologie, 51(7), 400-404 (2003-09-02) Anticancer activity of pristimerin in epidermal growth factor receptor 2-positive SKBR3 human breast cancer cells.Jin Sun Lee et al.Biological & pharmaceutical bulletin, 36(2), 316-325 (2013-02-02)

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