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Synthetic Route

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Peer-Reviewed Papers

Synthesis of 1-aminoisoquinolines via Rh(III)-catalyzed oxidative coupling.Xiaohong Wei et al.Organic letters, 13(17), 4636-4639 (2011-08-05) [A practical method for the synthesis of 1-aminoisoquinoline].S Giorgi-Renault et al.Annales pharmaceutiques francaises, 41(6), 555-557 (1983-01-01) Chemistry of stable iminopropadienones, RN=C=C=C=O.Hervé Bibas et al.The Journal of organic chemistry, 67(8), 2619-2631 (2002-04-13) 1-Aminoisoquinoline as benzamidine isoster in the design and synthesis of orally active thrombin inhibitors.J B Rewinkel et al.Bioorganic & medicinal chemistry letters, 9(5), 685-690 (1999-04-14) Large-scale application of high-throughput molecular mechanics with Poisson-Boltzmann surface area for routine physics-based scoring of protein-ligand complexes.Scott P Brown et al.Journal of medicinal chemistry, 52(10), 3159-3165 (2009-04-24) Recent developments in fragment-based drug discovery.Miles Congreve et al.Journal of medicinal chemistry, 51(13), 3661-3680 (2008-05-07) Selective inhibitors of the mutant B-Raf pathway: discovery of a potent and orally bioavailable aminoisoquinoline.Adrian L Smith et al.Journal of medicinal chemistry, 52(20), 6189-6192 (2009-09-22) Pathophysiological role of poly(ADP-ribose) polymerase (PARP) activation during acetaminophen-induced liver cell necrosis in mice.Cathleen Cover et al.Toxicological sciences : an official journal of the Society of Toxicology, 84(1), 201-208 (2004-12-17) An efficient route to 1-aminoisoquinolines via AgOTf-catalyzed reaction of 2-alkynylbenzaldoxime with amine.Danqing Zheng et al.Organic & biomolecular chemistry, 9(13), 4763-4765 (2011-05-28)

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