Melting point	>350 ºC**
Boiling point	233.8±40.0 ºC (760 Tor
Flash point	95.2±27.3 ºC, 计算值*
Density	1.432±0.06 g/cm3 (20 º

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Source	SDS/MSDS Samples
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Synthetic Route

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Articles

Peer-Reviewed Papers

Uridine Diphosphate-Glucuronosyltransferase (UGT) Xenobiotic Metabolizing Activity and Genetic Evolution in Pinniped Species.Mayu Kakehi et al.Toxicological sciences : an official journal of the Society of Toxicology, 147(2), 360-369 (2015-07-17) Firefighters' multiple exposure assessments in practice.Juha Laitinen et al.Toxicology letters, 213(1), 129-133 (2012-06-20) A fungal P450 (CYP5136A3) capable of oxidizing polycyclic aromatic hydrocarbons and endocrine disrupting alkylphenols: role of Trp(129) and Leu(324).Khajamohiddin Syed et al.PloS one, 6(12), e28286-e28286 (2011-12-14) Transporter-mediated uptake of UDP-glucuronic acid by human liver microsomes: assay conditions, kinetics, and inhibition.Andrew Rowland et al.Drug metabolism and disposition: the biological fate of chemicals, 43(1), 147-153 (2014-11-09) Detection of polycyclic aromatic hydrocarbons (PAHs) in raw menhaden fish oil using fluorescence spectroscopy: Method development.Edwin A Pena et al.Environmental toxicology and chemistry, 34(9), 1946-1958 (2015-04-14) Simultaneous HPLC-MS determination of 8-hydroxy-2'-deoxyguanosine, 3-hydroxyphenanthrene and 1-hydroxypyrene after online in-tube solid phase microextraction using a graphene oxide/poly(3,4-ethylenedioxythiophene)/polypyrrole composite.Dan Chen et al.Mikrochimica acta, 186(5), 300-300 (2019-04-27) A guidance value of 1-hydroxypyrene in urine in view of acceptable occupational exposure to polycyclic aromatic hydrocarbons.Frans J Jongeneelen Toxicology letters, 231(2), 239-248 (2014-05-17) Polycyclic aromatic hydrocarbons as plausible prebiotic membrane components.Joost Groen et al.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 42(4), 295-306 (2012-07-17) Electrospun nanofibers-based online micro-solid phase extraction for the determination of monohydroxy polycyclic aromatic hydrocarbons in human urine.Huifang Zhang et al.Journal of chromatography. A, 1521, 27-35 (2017-09-26) Benchmark guideline for urinary 1-hydroxypyrene as biomarker of occupational exposure to polycyclic aromatic hydrocarbons.F J Jongeneelen The Annals of occupational hygiene, 45(1), 3-13 (2001-01-04) Biomonitoring of polycyclic aromatic hydrocarbons from coke oven emissions and reproductive toxicity in nonsmoking workers.Hueiwang Anna Jeng et al.Journal of hazardous materials, 244-245, 436-443 (2013-01-15) Biomarkers of ambient air pollution and lung cancer: a systematic review.Christiana A Demetriou et al.Occupational and environmental medicine, 69(9), 619-627 (2012-07-10) The effect of occupational exposure to benzo[a]pyrene on neurobehavioral function in coke oven workers.Chongying Qiu et al.American journal of industrial medicine, 56(3), 347-355 (2012-09-22) Determination of hydroxylated polycyclic aromatic hydrocarbons by HPLC-photoionization tandem mass spectrometry in wood smoke particles and soil samples.Rozanna Avagyan et al.Analytical and bioanalytical chemistry, 407(16), 4523-4534 (2015-05-04) Bacillus subtilis is a potential degrader of pyrene and benzo[a]pyrene.Rochelle D Hunter et al.International journal of environmental research and public health, 2(2), 267-271 (2006-05-19) SPE-LC-MS investigations for the isolation and fractionation of acidic oil degradation products.Dieter Schemeth et al.Analytica chimica acta, 1038, 182-190 (2018-10-04) Simultaneous determination of 2-naphthol and 1-hydroxypyrene in fish and shellfish contaminated with crude oil by gas chromatography-mass spectrometry.Hyun-Hee Lim et al.Food chemistry, 138(2-3), 791-796 (2013-02-16) Biomarkers of polycyclic aromatic hydrocarbon exposure in European coke oven workers.Glenn Talaska et al.Toxicology letters, 231(2), 213-216 (2014-12-03) Environmental and biological monitoring of polycyclic aromatic hydrocarbon levels in outdoor workers exposed to urban stressor.A Sancini et al.Annali di igiene : medicina preventiva e di comunita, 24(5), 429-442 (2012-12-01) Levels of 1-hydroxypyrene in urine of people living in an oil producing region of the Andean Amazon (Ecuador and Peru).Jena Webb et al.International archives of occupational and environmental health, 91(1), 105-115 (2017-09-25) Whole-cell-dependent biosynthesis of sulfo-conjugate using human sulfotransferase expressing budding yeast.Miyu Nishikawa et al.Applied microbiology and biotechnology, 102(2), 723-732 (2017-11-15) Urinary levoglucosan levels in Austrian communities differing in agrarian quota.P Wallner et al.International journal of hygiene and environmental health, 216(3), 280-283 (2012-06-01) Burnt sugarcane harvesting: particulate matter exposure and the effects on lung function, oxidative stress, and urinary 1-hydroxypyrene.Gustavo Faibischew Prado et al.The Science of the total environment, 437, 200-208 (2012-09-04) Metabolites of the PAH diol epoxide pathway and other urinary biomarkers of phenanthrene and pyrene in workers with and without exposure to bitumen fumes.Anne Lotz et al.International archives of occupational and environmental health, 89(8), 1251-1267 (2016-08-12) A combined analytical method for biological monitoring of arsenic, benzene and polycyclic aromatic hydrocarbons in human urine by liquid chromatography tandem mass spectrometry.Fang-Chih Chang et al.Talanta, 198, 137-145 (2019-03-17) Electrospun core-shell nanofibers as an adsorbent for on-line micro-solid phase extraction of monohydroxy derivatives of polycyclic aromatic hydrocarbons from human urine, and their quantitation by LC-MS.Dan Chen et al.Mikrochimica acta, 187(1), 57-57 (2019-12-19) Heavy Exposure of Waste Collectors to Polycyclic Aromatic Hydrocarbons in a Poor Rural Area of Middle China.Jianheng Zheng et al.Environmental science & technology, 52(15), 8866-8875 (2018-07-03) Isoform-specific therapeutic control of sulfonation in humans.Ian Cook et al.Biochemical pharmacology, 159, 25-31 (2018-11-14) Oxidation of 1-chloropyrene by human CYP1 family and CYP2A subfamily cytochrome P450 enzymes: catalytic roles of two CYP1B1 and five CYP2A13 allelic variants.Tsutomu Shimada et al.Xenobiotica; the fate of foreign compounds in biological systems, 48(6), 565-575 (2017-06-27) Determination of oxygen and nitrogen derivatives of polycyclic aromatic hydrocarbons in fractions of asphalt mixtures using liquid chromatography coupled to mass spectrometry with atmospheric pressure chemical ionization.Paulo Cicero Nascimento et al.Journal of separation science, 38(23), 4055-4062 (2015-10-09) Tetrahydrobiopterin regulates monoamine neurotransmitter sulfonation.Ian Cook et al.Proceedings of the National Academy of Sciences of the United States of America, 114(27), E5317-E5324 (2017-06-21) Assessment of the levels of persistent organic pollutants and 1-hydroxypyrene in blood and urine samples from Mexican children living in an endemic malaria area in Mexico.Antonio Trejo-Acevedo et al.Bulletin of environmental contamination and toxicology, 88(6), 828-832 (2012-03-15) A novel analytical methodology for the determination of hydroxy polycyclic aromatic hydrocarbons in breast and cow milk samples.E Martin-Tornero et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1136, 121912-121912 (2019-12-17) Biological monitoring of environmental exposure to polycyclic aromatic hydrocarbons; 1-hydroxypyrene in urine of people.F J Jongeneelen Toxicology letters, 72(1-3), 205-211 (1994-06-01) Determination of 1-hydroxypyrene in human urine by HPLC with electrochemical detection at a boron-doped diamond film electrode.Oksana Yosypchuk et al.Analytical and bioanalytical chemistry, 404(3), 693-699 (2012-06-15) Urinary 1-hydroxypyrene (1-HP) in environmental and occupational studies--a review.Ase M Hansen et al.International journal of hygiene and environmental health, 211(5-6), 471-503 (2008-01-29) DDT, DDE, and 1-hydroxypyrene levels in children (in blood and urine samples) from Chiapas and Oaxaca, Mexico.Iván N Pérez-Maldonado et al.Environmental monitoring and assessment, 185(11), 9287-9293 (2013-05-28) ETS Exposure and PAH Body Burden in Nonsmoking Italian Adults.Laura Campo et al.International journal of environmental research and public health, 15(6) (2018-06-06) Exposure to chemical mixtures in Mexican children: high-risk scenarios.Gabriela Domínguez-Cortinas et al.Environmental science and pollution research international, 20(1), 351-357 (2012-05-01) Electrospun polystyrene/graphene nanofiber film as a novel adsorbent of thin film microextraction for extraction of aldehydes in human exhaled breath condensates.Jing Huang et al.Analytica chimica acta, 878, 102-108 (2015-05-24) Synchronous fluorescence spectrometry of 1-hydroxypyrene: a rapid screening method for identification of PAH exposure in tissue from marine polychaetes.Anders M B Giessing et al.Marine environmental research, 56(5), 599-615 (2003-08-21) 1-hydroxypyrene levels in blood samples of rats after exposure to generator fumes.Clinton Ifegwu et al.Biomarkers in cancer, 5, 1-6 (2013-11-02) [Assessment of exposure to polycyclic aromatic hydrocarbons in asphalt workers by measurement of urinary 1-hydroxypyrene].Laura Campo et al.La Medicina del lavoro, 102(6), 484-493 (2012-02-16) Assessing hazardous risks of indoor airborne polycyclic aromatic hydrocarbons in the kitchen and its association with lung functions and urinary PAH metabolites in kitchen workers.Amarnath Singh et al.Clinica chimica acta; international journal of clinical chemistry, 452, 204-213 (2015-12-01) Comparison of Bladder Carcinogens in the Urine of E-cigarette Users Versus Non E-cigarette Using Controls.Thomas W Fuller et al.Scientific reports, 8(1), 507-507 (2018-01-13) Environmental and biological monitoring of PAHs exposure in coke-oven workers at the Taranto plant compared to two groups from the general population of Apulia, Italy.Laura Campo et al.La Medicina del lavoro, 103(5), 347-360 (2012-10-20) Facile preparation of a cationic COF functionalized magnetic nanoparticle and its use for the determination of nine hydroxylated polycyclic aromatic hydrocarbons in smokers' urine.Wenfen Zhang et al.The Analyst, 144(19), 5829-5841 (2019-09-03) Photo-induced toxicity and oxidative stress responses in Tigriopus japonicus exposed to nitro-polycyclic aromatic hydrocarbons and artificial light.Toshimitsu Onduka et al.Chemosphere, 169, 596-603 (2016-12-03) Hydroxylation of non-substituted polycyclic aromatic hydrocarbons by cytochrome P450 BM3 engineered by directed evolution.Anastasia Sideri et al.Journal of inorganic biochemistry, 120, 1-7 (2012-12-25) Human Cytosolic Sulphotransferase SULT1C3: genomic analysis and functional characterization of splice variant SULT1C3a and SULT1C3d.Katsuhisa Kurogi et al.Journal of biochemistry, 162(6), 403-414 (2017-10-11) Association of aryl hydrocarbon receptor gene polymorphism with the neurobehavioral function and autonomic nervous system function changes induced by benzo[a]pyrene exposure in coke oven workers.Hongmei Zhang et al.Journal of occupational and environmental medicine, 55(3), 265-271 (2013-02-27) Hebei spirit oil spill exposure and subjective symptoms in residents participating in clean-up activities.Hae-Kwan Cheong et al.Environmental health and toxicology, 26, e2011007-e2011007 (2011-11-30) Bioaccumulation and metabolisation of (14)C-pyrene by the Pacific oyster Crassostrea gigas exposed via seawater.P Bustamante et al.Chemosphere, 87(8), 938-944 (2012-02-22) Korea National Survey for Environmental Pollutants in the human body 2008: 1-hydroxypyrene, 2-naphthol, and cotinine in urine of the Korean population.Donggeun Sul et al.Environmental research, 118, 25-30 (2012-09-04) Exposure to PAH compounds among cokery workers in the oil shale industry.T Kuljukka et al.Environmental health perspectives, 104 Suppl 3, 539-541 (1996-05-01) Liposomes with asymmetric bilayers produced from inverse emulsions for nucleic acid delivery.Maria B C de Matos et al.Journal of drug targeting, 27(5-6), 681-689 (2019-02-13) Commuting behaviors and exposure to air pollution in Montreal, Canada.Qun Miao et al.The Science of the total environment, 508, 193-198 (2014-12-06) Quantification of urinary mono-hydroxylated metabolites of polycyclic aromatic hydrocarbons by on-line solid phase extraction-high performance liquid chromatography-tandem mass spectrometry.Yuesong Wang et al.Analytical and bioanalytical chemistry, 409(4), 931-937 (2016-11-01) Characterization of function and genetic feature of UDP-glucuronosyltransferase in avian species.Yusuke K Kawai et al.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 217, 5-14 (2018-11-27) Assessment of DDT, DDE, and 1-hydroxypyrene levels in blood and urine samples in children from Chiapas Mexico.Rebeca I Martínez-salinas et al.Environmental science and pollution research international, 19(7), 2658-2666 (2012-01-28) Urinary 1-hydroxypyrene as a biomarker to carcinogenic polycyclic aromatic hydrocarbon exposure.Clinton Ifegwu et al.Biomarkers in cancer, 4, 7-17 (2012-01-01) Assessment of the levels of urinary 1-hydroxypyrene and air polycyclic aromatic hydrocarbon in PM2.5 for adult exposure to the petrochemical complex emissions.Tzu-Hsuen Yuan et al.Environmental research, 136, 219-226 (2014-12-03) Photodegradation mechanisms of 1-nitropyrene, an environmental pollutant: the effect of organic solvents, water, oxygen, phenols, and polycyclic aromatics on the destruction and product yields.Zulma I García-Berríos et al.The journal of physical chemistry. A, 116(14), 3652-3664 (2012-03-31) Comparative study of different exposure routes on the biotransformation and genotoxicity of PAHs in the flatfish species, Scophthalmus maximus.Marie Le Dû-Lacoste et al.Environmental science and pollution research international, 20(2), 690-707 (2012-12-19) Physiologically-based toxicokinetic models help identifying the key factors affecting contaminant uptake during flood events.Markus Brinkmann et al.Aquatic toxicology (Amsterdam, Netherlands), 152, 38-46 (2014-04-15) Studying the effectiveness of activated carbon R95 respirators in reducing the inhalation of combustion by-products in Hanoi, Vietnam: a demonstration study.Heiman F L Wertheim et al.Environmental health : a global access science source, 11, 72-72 (2012-09-28) Oxidative stress and respiratory symptoms due to human exposure to polycyclic aromatic hydrocarbons (PAHs) in Kumasi, Ghana.Nesta Bortey-Sam et al.Environmental pollution (Barking, Essex : 1987), 228, 311-320 (2017-05-30) Inorganic-organic hybrid coating material for the online in-tube solid-phase microextraction of monohydroxy polycyclic aromatic hydrocarbons in urine.ShuLing Wang et al.Journal of separation science, 39(23), 4610-4620 (2016-10-18) Electrospun polystyrene/oxidized carbon nanotubes film as both sorbent for thin film microextraction and matrix for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.Xiao-Mei He et al.Journal of chromatography. A, 1351, 29-36 (2014-06-09) Mouth-level intake of benzo[a]pyrene from reduced nicotine cigarettes.Yan S Ding et al.International journal of environmental research and public health, 11(11), 11898-11914 (2014-11-21) A gold nanoparticle-based colorimetric probe for rapid detection of 1-hydroxypyrene in urine.Yaqi Hu et al.The Analyst, 140(13), 4662-4667 (2015-05-20) 1-Hydroxypyrene as a biomarker for assessing the effects of exposure to polycyclic aromatic hydrocarbons on semen quality and sperm DNA integrity.Hueiwang Anna Jeng et al.Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 48(2), 152-158 (2012-10-10) Excretion profiles and half-lives of ten urinary polycyclic aromatic hydrocarbon metabolites after dietary exposure.Zheng Li et al.Chemical research in toxicology, 25(7), 1452-1461 (2012-06-06) Target and suspect screening of OH-PAHs in air particulates using liquid chromatography-orbitrap high resolution mass spectrometry.Rozanna Avagyan et al.Talanta, 165, 702-708 (2017-02-06) A gold nanoparticle-based colorimetric probe for rapid detection of 1-hydroxypyrene in urine.Yaqi Hu et al.The Analyst, 140(13), 4662-4667 (2015-05-20) Quantification of monohydroxylated polycyclic aromatic hydrocarbons in human urine samples using solid-phase microextraction coupled with glass-capillary nanoelectrospray ionization mass spectrometry.Bi-Cheng Yang et al.Analytica chimica acta, 973, 68-74 (2017-05-16) Exposure to cooking oil fumes and oxidative damages: a longitudinal study in Chinese military cooks.Ching-Huang Lai et al.Journal of exposure science & environmental epidemiology, 23(1), 94-100 (2012-09-13) Oxidation and adduct formation of xenobiotics in a microfluidic electrochemical cell with boron doped diamond electrodes and an integrated passive gradient rotation mixer.Floris T G van den Brink et al.Lab on a chip, 16(20), 3990-4001 (2016-10-11) The determination of occupational exposure to polycyclic aromatic hydrocarbons by the analysis of 1-hydroxypyrene in urine using a simple automated online column switching device and high-performance liquid chromatography.Jimmy Hu et al.Journal of analytical toxicology, 36(5), 334-339 (2012-05-15) Urinary 1-hydroxypyrene and other PAH metabolites as biomarkers of exposure to environmental PAH in air particulate matter.P Strickland et al.Toxicology letters, 108(2-3), 191-199 (1999-10-08) Urinary 1-hydroxypyrene is associated with oxidative stress and inflammatory biomarkers in acute Myocardial Infarction.Fernando Freitas et al.International journal of environmental research and public health, 11(9), 9024-9037 (2014-09-27) Exposure to polycyclic aromatic hydrocarbons, vitamin D, and lung function in children with asthma.Yueh-Ying Han et al.Pediatric pulmonology, 53(10), 1362-1368 (2018-06-27)

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