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Scyllitol | CAS:488-59-5
Scyllitol
  • Name:Scyllitol
  • CAS:488-59-5
  • Synonyms:AZD 103; Cocositol; ELND 005; Quercinitol; scyllo-Cyclohexanehexol
  • Molecular Formula:C6H12O6
  • Molecular Weight:180.16
  • EINESC:

Description

Properties

Melting point 367 ºC (water )**
Density 2.038±0.06 g/cm3 (20 º

Safety

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SDS

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Synthetic Route
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Articles
Peer-Reviewed Papers
Fomepizole for the treatment of pediatric ethylene and diethylene glycol, butoxyethanol, and methanol poisonings.Jeffrey Brent Clinical toxicology (Philadelphia, Pa.), 48(5), 401-406 (2010-07-01) RNA-seq Transcriptional Profiling of an Arbuscular Mycorrhiza Provides Insights into Regulated and Coordinated Gene Expression in Lotus japonicus and Rhizophagus irregularis.Yoshihiro Handa et al.Plant & cell physiology, 56(8), 1490-1511 (2015-05-27) Systematic toxicity mechanism analysis of proton pump inhibitors: an in silico study.Dingfeng Wu et al.Chemical research in toxicology, 28(3), 419-430 (2015-01-28) Ingestion of smoke fluid: Be aware of diethylene glycol.Agnes van Velzen et al.Clinical toxicology (Philadelphia, Pa.), 51(9), 907-907 (2013-09-03) Diethylene glycol-induced toxicities show marked threshold dose response in rats.Greg M Landry et al.Toxicology and applied pharmacology, 282(3), 244-251 (2014-12-30) Ferrimagnetic nanocrystal assemblies as versatile magnetic particle hyperthermia mediators.D Sakellari et al.Materials science & engineering. C, Materials for biological applications, 58, 187-193 (2015-10-20) Inhibition of polyethylene glycol-induced histamine release by monomeric ethylene and diethylene glycol: a case of probable polyethylene glycol allergy.Emily Cathrine Wenande et al.The Journal of allergy and clinical immunology, 131(5), 1425-1427 (2012-12-12) Phytoremediaton of diethylene glycol contaminated wastewater by Echinodorus cordifolius.W Sriprapat et al.International journal of phytoremediation, 13(6), 592-600 (2011-10-07) Quantitative evaluation of the sensitivity of library-based Raman spectral correlation methods.Jason D Rodriguez et al.Analytical chemistry, 83(11), 4061-4067 (2011-05-10) Development of topical hydrogels of terbinafine hydrochloride and evaluation of their antifungal activity.Nevin Çelebi et al.Drug development and industrial pharmacy, 41(4), 631-639 (2014-03-01) MRI visible drug eluting magnetic microspheres for transcatheter intra-arterial delivery to liver tumors.Dong-Hyun Kim et al.Theranostics, 5(5), 477-488 (2015-03-15) Dynamic changes in host gene expression associated with H5N8 avian influenza virus infection in mice.Su-Jin Park et al.Scientific reports, 5, 16512-16512 (2015-11-19) Palladium-platinum core-shell icosahedra with substantially enhanced activity and durability towards oxygen reduction.Xue Wang et al.Nature communications, 6, 7594-7594 (2015-07-03) Superparamagnetic iron oxide nanoparticles with variable size and an iron oxidation state as prospective imaging agents.Pavel Kucheryavy et al.Langmuir : the ACS journal of surfaces and colloids, 29(2), 710-716 (2012-12-20) Magnetic field-induced self-assembly of iron oxide nanocubes.Gurvinder Singh et al.Faraday discussions, 181, 403-421 (2015-04-30) Analysis of Stage-Specific Gene Expression Profiles in the Uterine Endometrium during Pregnancy in Pigs.Mingoo Kim et al.PloS one, 10(11), e0143436-e0143436 (2015-11-19) Characterization of the cork oak transcriptome dynamics during acorn development.Andreia Miguel et al.BMC plant biology, 15, 158-158 (2015-06-26) Impact of agglomeration on the relaxometric properties of paramagnetic ultra-small gadolinium oxide nanoparticles.Luc Faucher et al.Nanotechnology, 22(29), 295103-295103 (2011-06-23) Reformulating polycaprolactone fumarate to eliminate toxic diethylene glycol: effects of polymeric branching and autoclave sterilization on material properties.M Brett Runge et al.Acta biomaterialia, 8(1), 133-143 (2011-09-14) Synthesis and characterization of conformationally preorganized, (R)-diethylene glycol-containing γ-peptide nucleic acids with superior hybridization properties and water solubility.Bichismita Sahu et al.The Journal of organic chemistry, 76(14), 5614-5627 (2011-05-31) Strand-Specific RNA-Seq Analyses of Fruiting Body Development in Coprinopsis cinerea.Hajime Muraguchi et al.PloS one, 10(10), e0141586-e0141586 (2015-10-29) Gene expression associated with white syndromes in a reef building coral, Acropora hyacinthus.Rachel M Wright et al.BMC genomics, 16, 371-371 (2015-05-10) Effects of valproic acid and dexamethasone administration on early bio-markers and gene expression profile in acute kidney ischemia-reperfusion injury in the rat.Ryan W Speir et al.PloS one, 10(5), e0126622-e0126622 (2015-05-15) Separation of preferential interaction and excluded volume effects on DNA duplex and hairpin stability.D B Knowles et al.Proceedings of the National Academy of Sciences of the United States of America, 108(31), 12699-12704 (2011-07-12) Chain length dependence of polyol synthesis of zinc ferrite nanoparticles: why is diethylene glycol so different?Supriya N Rishikeshi et al.Dalton transactions (Cambridge, England : 2003), 42(15), 5430-5438 (2013-02-21) Lethal and sublethal endpoints observed for Artemia exposed to two reference toxicants and an ecotoxicological concern organic compound.Loredana Manfra et al.Ecotoxicology and environmental safety, 123, 60-64 (2015-09-08) Determining minimum set of driver nodes in protein-protein interaction networks.Xiao-Fei Zhang et al.BMC bioinformatics, 16, 146-146 (2015-05-08) Lactone metabolite common to the carcinogens dioxane, diethylene glycol, and N-nitrosomorpholine: aqueous chemistry and failure to mediate liver carcinogenesis in the F344 rat.Niangoran Koissi et al.Chemical research in toxicology, 25(5), 1022-1028 (2012-03-31) Single-cell mechanics--An experimental-computational method for quantifying the membrane-cytoskeleton elasticity of cells.M Tartibi et al.Acta biomaterialia, 27, 224-235 (2015-08-25) Stage of lactation and corresponding diets affect in situ protein degradation by dairy cows.I Schadt et al.Journal of dairy science, 97(12), 7995-8007 (2014-10-06) Ligand-induced fate of embryonic species in the shape-controlled synthesis of rhodium nanoparticles.Adam J Biacchi et al.ACS nano, 9(2), 1707-1720 (2015-01-30) A Processable Shape Memory Polymer System for Biomedical Applications.Keith Hearon et al.Advanced healthcare materials, 4(9), 1386-1398 (2015-05-01) Oxidation of diethylene glycol with ozone and modified Fenton processes.Tuba Turan-Ertas et al.Chemosphere, 47(3), 293-301 (2002-05-09) Transcriptome changes in Eriocheir sinensis megalopae after desalination provide insights into osmoregulation and stress adaption in larvae.Min Hui et al.PloS one, 9(12), e114187-e114187 (2014-12-04) Controlled synthesis of Fe3O4/ZIF-8 nanoparticles for magnetically separable nanocatalysts.Fei Pang et al.Chemistry (Weinheim an der Bergstrasse, Germany), 21(18), 6879-6887 (2015-03-15) Synthesis of biodegradable polymers using biocatalysis with Yarrowia lipolytica lipase.Karla A Barrera-Rivera et al.Methods in molecular biology (Clifton, N.J.), 861, 485-493 (2012-03-20) Rising above helium: A hydrogen carrier gas chromatography flame ionization detection (GC-FID) method for the simultaneous quantification of toxic alcohols and ethylene glycol in human plasma specimens.Joshua Buse et al.Clinical biochemistry, 73, 98-104 (2019-08-20) Pre-existing liver cirrhosis reduced the toxic effect of diethylene glycol in a rat model due to the impaired hepatic alcohol dehydrogenase.Ming Xing Huang et al.Toxicology and industrial health, 27(8), 742-753 (2011-05-06) Inhaled ozone (O3)-induces changes in serum metabolomic and liver transcriptomic profiles in rats.Desinia B Miller et al.Toxicology and applied pharmacology, 286(2), 65-79 (2015-04-04) Comparative transcriptome profiling of the early infection of wheat roots by Gaeumannomyces graminis var. tritici.Lirong Yang et al.PloS one, 10(4), e0120691-e0120691 (2015-04-16) Role of tissue metabolite accumulation in the renal toxicity of diethylene glycol.Lauren M Besenhofer et al.Toxicological sciences : an official journal of the Society of Toxicology, 123(2), 374-383 (2011-08-02) Hypothalamic differences in expression of genes involved in monoamine synthesis and signaling pathways after insulin injection in chickens from lines selected for high and low body weight.Wei Zhang et al.Neurogenetics, 16(2), 133-144 (2015-01-15) Acute high-level exposure to WTC particles alters expression of genes associated with oxidative stress and immune function in the lung.Mitchell D Cohen et al.Journal of immunotoxicology, 12(2), 140-153 (2014-06-10) Characterizing concentrations of diethylene glycol and suspected metabolites in human serum, urine, and cerebrospinal fluid samples from the Panama DEG mass poisoning.J G Schier et al.Clinical toxicology (Philadelphia, Pa.), 51(10), 923-929 (2013-11-26) The BRCA1/2-directed miRNA signature predicts a good prognosis in ovarian cancer patients with wild-type BRCA1/2.Yunyan Gu et al.Oncotarget, 6(4), 2397-2406 (2014-12-30) A transferable force field to predict phase equilibria and surface tension of ethers and glycol ethers.Nicolas Ferrando et al.The journal of physical chemistry. B, 115(36), 10654-10664 (2011-08-02) Determination of solubility parameters of ionic liquids and ionic liquid/solvent mixtures from intrinsic viscosity.Piyarat Weerachanchai et al.Chemphyschem : a European journal of chemical physics and physical chemistry, 15(16), 3580-3591 (2014-08-26) [Acute human and experimental poisoning with diethylene glycol].J L Hébert et al.La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 59(5), 344-349 (1983-02-03) Metabolite profiling of red and white pitayas (Hylocereus polyrhizus and Hylocereus undatus) for comparing betalain biosynthesis and antioxidant activity.Dong Ho Suh et al.Journal of agricultural and food chemistry, 62(34), 8764-8771 (2014-08-08) Transcriptional cellular responses in midgut tissue of Aedes aegypti larvae following intoxication with Cry11Aa toxin from Bacillus thuringiensis.Pablo Emiliano Canton et al.BMC genomics, 16, 1042-1042 (2015-12-10) Correlation between Energy and Spatial Distribution of Intragap Trap States in the TiO2 Photoanode of Dye-Sensitized Solar Cells.Yi Wang et al.Chemphyschem : a European journal of chemical physics and physical chemistry, 16(10), 2253-2259 (2015-04-29) Metallo-supramolecular diethylene glycol: water-soluble reversible polymers.Schmatloch S, et al. Macromolecular Rapid Communications, 23(16), 957-961 (2002) Self-cleaning Metal Organic Framework (MOF) based ultra filtration membranes--a solution to bio-fouling in membrane separation processes.J A Prince et al.Scientific reports, 4, 6555-6555 (2014-10-10) Clinical, laboratory, diagnostic, and histopathologic features of diethylene glycol poisoning--Panama, 2006.Nestor R Sosa et al.Annals of emergency medicine, 64(1), 38-47 (2014-01-21) Bioluminescent liquid light guide pad biosensor for indoor air toxicity monitoring.Evgeni Eltzov et al.Analytical chemistry, 87(7), 3655-3661 (2015-03-17) Applicability of a newly developed bioassay for determining bioactivity of anti-inflammatory compounds in release studies--celecoxib and triamcinolone acetonide released from novel PLGA-based microspheres.Hsiao-yin Yang et al.Pharmaceutical research, 32(2), 680-690 (2014-08-29) De Novo Transcriptome Sequencing of the Orange-Fleshed Sweet Potato and Analysis of Differentially Expressed Genes Related to Carotenoid Biosynthesis.Ruijie Li et al.International journal of genomics, 2015, 843802-843802 (2015-12-10) In situ formation of adhesive hydrogels based on PL with laterally grafted catechol groups and their bonding efficacy to wet organic substrates.Mingming Ye et al.Journal of materials science. Materials in medicine, 26(12), 273-273 (2015-11-01) Diethylene glycol poisoning.Schep LJ, et al. Clinical Toxicology, 47(6), 525-535 (2009) Dynamic changes of RNA-sequencing expression for precision medicine: N-of-1-pathways Mahalanobis distance within pathways of single subjects predicts breast cancer survival.A Grant Schissler et al.Bioinformatics (Oxford, England), 31(12), i293-i302 (2015-06-15) The estrous cycle surpasses sex differences in regulating the transcriptome in the rat medial prefrontal cortex and reveals an underlying role of early growth response 1.Florian Duclot et al.Genome biology, 16, 256-256 (2015-12-03) Unravelling personalized dysfunctional gene network of complex diseases based on differential network model.Xiangtian Yu et al.Journal of translational medicine, 13, 189-189 (2015-06-14) Diethylene glycol poisoning.Leo J Schep et al.Clinical toxicology (Philadelphia, Pa.), 47(6), 525-535 (2009-07-10) Capillary atmospheric pressure chemical ionization using liquid point electrodes.Sonja Klee et al.Rapid communications in mass spectrometry : RCM, 28(14), 1591-1600 (2014-06-05) High-Performance Flexible All-Solid-State Supercapacitor from Large Free-Standing Graphene-PEDOT/PSS Films.Yuqing Liu et al.Scientific reports, 5, 17045-17045 (2015-11-21) Analysis of eight glycols in serum using LC-ESI-MS-MS.Laurent Imbert et al.Journal of analytical toxicology, 38(9), 676-680 (2014-09-05) Molecularly imprinted upconversion nanoparticles for highly selective and sensitive sensing of Cytochrome c.Ting Guo et al.Biosensors & bioelectronics, 74, 498-503 (2015-07-16) Two centuries of assessing drug risks.Jerry Avorn The New England journal of medicine, 367(3), 193-197 (2012-07-20) Glycodendrimeric phenylporphyrins as new candidates for retinoblastoma PDT: blood carriers and photodynamic activity in cells.Ze-Jian Wang et al.Journal of photochemistry and photobiology. B, Biology, 115, 16-24 (2012-07-17) Migrating components in a polyurethane laminating adhesive identified using gas chromatography/mass spectrometry.Behnusch Athenstädt et al.Rapid communications in mass spectrometry : RCM, 26(16), 1810-1816 (2012-07-11) Medication-associated diethylene glycol mass poisoning: a review and discussion on the origin of contamination.Joshua G Schier et al.Journal of public health policy, 30(2), 127-143 (2009-07-15) Confrontation of fibroblasts with cancer cells in vitro: gene network analysis of transcriptome changes and differential capacity to inhibit tumor growth.Andrey Alexeyenko et al.Journal of experimental & clinical cancer research : CR, 34, 62-62 (2015-06-18) Influence of Sex on Basal and Dickkopf-1 Regulated Gene Expression in the Bovine Morula.Anna C Denicol et al.PloS one, 10(7), e0133587-e0133587 (2015-07-22) Effects of hydrogen bonding on the monolayer properties of amphiphilic double-decker-shaped polyhedral silsesquioxanes.Asuman C Kucuk et al.Langmuir : the ACS journal of surfaces and colloids, 27(10), 6381-6388 (2011-04-16) Diethylene glycol functionalized self-assembling peptide nanofibers and their hydrophobic drug delivery potential.Parisa Sadatmousavi et al.Acta biomaterialia, 8(9), 3241-3250 (2012-05-30) Getting the most out of RNA-seq data analysis.Tsung Fei Khang et al.PeerJ, 3, e1360-e1360 (2015-11-06) Reduced graphene oxide/carbon double-coated 3-D porous ZnO aggregates as high-performance Li-ion anode materials.Sungun Wi et al.Nanoscale research letters, 10, 204-204 (2015-05-16) Diglycolic acid is the nephrotoxic metabolite in diethylene glycol poisoning inducing necrosis in human proximal tubule cells in vitro.Greg M Landry et al.Toxicological sciences : an official journal of the Society of Toxicology, 124(1), 35-44 (2011-08-23) Toxicity evaluation of diethylene glycol and its combined effects with produced waters of off-shore gas platforms in the Adriatic Sea (Italy): bioassays with marine/estuarine species.Andrea Tornambè et al.Marine environmental research, 77, 141-149 (2012-01-17) Delayed neurological sequelae from ethylene glycol, diethylene glycol and methanol poisonings.Nandi J Reddy et al.Clinical toxicology (Philadelphia, Pa.), 48(10), 967-973 (2011-01-05) Thermoplastic elastomers derived from menthide and tulipalin A.Jihoon Shin et al.Biomacromolecules, 13(11), 3833-3840 (2012-10-16) Degradation mechanism of diethylene glycol units in a terephthalate polymer.Lecomte HA and Liggat. 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