Melting point	98-104 ºC

Symbol(GHS)	Xi
Hazard Codes	R36/37/38
SDS/MSDS	S26;S36/37

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Distal effects in a model of proximal axonopathy: 3,3'-iminodipropionitrile causes specific loss of neurofilaments in rat vestibular afferent endings.Ana Seoane et al.Acta neuropathologica, 106(5), 458-470 (2003-08-05) Inhibitory effect of free radical scavenger, MCI-186, in the increase of hydroxyl radical induced by iminodipropionitrile in rats.Nobuatsu Nomoto Journal of the neurological sciences, 219(1-2), 41-44 (2004-03-31) N-nitro-L-arginine, a nitric oxide synthase inhibitor, aggravates iminodipropionitrile-induced neurobehavioral and vestibular toxicities in rats.Haseeb Ahmad Khan Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 64(7-8), 791-796 (2011-03-11) Loss of neurofilaments in the neuromuscular junction in a rat model of proximal axonopathy.C Soler-Martín et al.Neuropathology and applied neurobiology, 38(1), 61-71 (2011-04-01) Domino alkylation/oxa-Michael of 1,3-cyclohexanediones: steering the C/O-chemoselectivity to reach tetrahydrobenzofuranones.Rema B Devi et al.Organic & biomolecular chemistry, 9(19), 6509-6512 (2011-08-10) Gastrodin alleviates Tourette syndrome via Nrf-2/HO-1/HMGB1/NF-кB pathway.Hongyan Long et al.Journal of biochemical and molecular toxicology, 33(10), e22389-e22389 (2019-08-31) Neurovestibular toxicities of acrylonitrile and iminodipropionitrile in rats: a comparative evaluation of putative mechanisms and target sites.Haseeb Ahmad Khan et al.Toxicological sciences : an official journal of the Society of Toxicology, 109(1), 124-131 (2009-02-27) Acute reproductive toxicity of 3,3'-iminodipropionitrile in female rats.Noriyuki Takahashi et al.Reproductive toxicology (Elmsford, N.Y.), 33(1), 27-34 (2011-11-15) Selective atonal gene delivery improves balance function in a mouse model of vestibular disease.C Schlecker et al.Gene therapy, 18(9), 884-890 (2011-04-08) Toxic neurofilamentous axonopathies -- accumulation of neurofilaments and axonal degeneration.J Llorens Journal of internal medicine, 273(5), 478-489 (2013-01-22) Aberrant epigenetic gene regulation in hippocampal neurogenesis of mouse offspring following maternal exposure to 3,3'-iminodipropionitrile.Takeshi Tanaka et al.The Journal of toxicological sciences, 44(2), 93-105 (2019-02-07) Behavioral disturbances and hair cell loss in the inner ear following nitrile exposure in mice, guinea pigs, and frogs.Carla Soler-Martín et al.Toxicological sciences : an official journal of the Society of Toxicology, 96(1), 123-132 (2006-12-13) Differential performance of Wistar Han and Sprague Dawley rats in behavioral tests: differences in baseline behavior and reactivity to positive control agents.Amy Zmarowski et al.Reproductive toxicology (Elmsford, N.Y.), 34(2), 192-203 (2012-06-06) Does copper ameliorate the vestibular toxicity of iminodipropionitrile (IDPN)?J Llorens Neurotoxicology, 26(3), 475-476 (2005-05-12) Mechanism of neurotoxic 3,3'-iminodipropionitrile: relation to unsaturated nitriles, cocaine, and reactive oxygen species.Peter Kovacic Medical hypotheses, 66(1), 210-211 (2005-09-29) Expression of neurotransmitter genes in motor regions of the dyskinetic rat after iminodipropionitrile.J A Fritschi et al.Neuroscience letters, 347(1), 45-48 (2003-07-17) Nervous and vestibular toxicities of acrylonitrile and iminodipropionitrile.Jordi Llorens et al.Toxicological sciences : an official journal of the Society of Toxicology, 110(1), 244-245 (2009-05-01) Pentoxifylline attenuates iminodipropionitrile-induced behavioral abnormalities in rats.Saeed Al Kadasah et al.Behavioural pharmacology, 20(4), 356-360 (2009-07-09) The neurotoxicity of iminodipropionitrile (IDPN) is ameliorated by copper.Henrik A Hartmann Neurotoxicology, 26(2), 277-283 (2005-02-17) The involvement of neurofilament heavy chain phosphorylation in the maturation and degeneration of rat oocytes.Noriyuki Takahashi et al.Endocrinology, 153(4), 1990-1998 (2012-02-09) Protective effect of hydrocortisone on iminodipropionitrile-induced neurotoxicity in rats.Mohammad Tariq et al.Basic & clinical pharmacology & toxicology, 100(3), 176-181 (2007-02-21) [Neurobehavioral toxicity of acrylamide and IDPN (3,3'-iminodipropionitrile) in rats by 28-day oral administration--problems encountered in collaborative study and a commentary on conducting neurobehavioral testing].Shuzo Okazaki et al.The Journal of toxicological sciences, 28 Suppl 1, 1-14 (2003-06-26) Influence of age on iminodipropionitrile-induced vestibular and neurobehavioral toxicities in rats.Haseeb Ahmad Khan et al.Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 55(2-3), 181-186 (2003-11-19) Sodium benzoate attenuates iminodipropionitrile-induced behavioral syndrome in rats.M Tariq et al.Behavioural pharmacology, 15(8), 585-588 (2004-12-04) Cooperative roles of PAK1 and filamin A in regulation of vimentin assembly and cell extension formation.Isabel Ding et al.Biochimica et biophysica acta. Molecular cell research, 1867(9), 118739-118739 (2020-05-12) Butenenitriles have low axonopathic potential in the rat.Carla Soler-Martín et al.Toxicology letters, 200(3), 187-193 (2010-12-04) Propagation of scrapie in peripheral nerves after footpad infection in normal and neurotoxin exposed hamsters.Christine Kratzel et al.Veterinary research, 38(1), 127-139 (2006-12-22) Chronic proximal axonopathy in rats is associated with long-standing neurofilament depletion in neuromuscular junctions and behavioral deficits.Carla Soler-Martín et al.Journal of neuropathology and experimental neurology, 73(6), 568-579 (2014-05-09) Surface chemical conversion of 3-glycidoxypropyldimethylethoxysilane on hydroxylated silicon surface: FT-IR, contact angle and ellipsometry analysis.Serkan Demirci et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 99, 144-149 (2012-10-16)

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