
Hexahydropyridazin | CAS:505-19-1
Hexahydropyridazin
- Name:Hexahydropyridazin
- CAS:505-19-1
- Synonyms:Diazinane
- Molecular Formula:C4H10N2
- Molecular Weight:86.13
- EINESC:
Description
Properties
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Safety
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SDS
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Synthetic Route
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Articles
Peer-Reviewed Papers
Protective effects of zymosan on heat stress-induced immunosuppression and apoptosis in dairy cows and peripheral blood mononuclear cells.Yuhang Sun et al.Cell stress & chaperones, 23(5), 1069-1078 (2018-06-04)
The role of properdin in zymosan-and Escherichia coli-induced complement activationHarboe M, et al. Journal of immunology (Baltimore, Md. : 1950), 1200269-1200269 (2012)
Expression of endoglin isoforms in the myeloid lineage and their role during aging and macrophage polarization.Mikel Aristorena et al.Journal of cell science, 127(Pt 12), 2723-2735 (2014-04-30)
Zymosan Priming Protects Rats Against Pulmonary Oxygen Toxicity: Characterization Of The Model.Berg, J.T. Exp. Biol. Med, 235, 170-174 (2010)
ACUTE INFLAMMATION AND RECOVERY IN RATS AFTER INTRATRACHEAL INSTILLATION OF A 1?3-Young SH, et al. Journal of Toxicology and Environmental Health. Part A, 64(4), 311-325 (2001)
Curvature of synthetic and natural surfaces is an important target feature in classical pathway complement activation.Martin Bjerregård Pedersen et al.Journal of immunology (Baltimore, Md. : 1950), 184(4), 1931-1945 (2010-01-08)
Enhanced orbital adipogenesis in a mouse model of T-cell-mediated autoimmunity, zymosan A-treated SKG mice: Implications for Graves' ophthalmopathy.Sera Park et al.Scientific reports, 10(1), 7329-7329 (2020-05-02)
The role of Syk/IĸB-α/NF-ĸB pathway activation in the reversal effect of BAY 61-3606, a selective Syk inhibitor, on hypotension and inflammation in a rat model of zymosan-induced non-septic shock.Demet Unsal et al.Clinical and experimental pharmacology & physiology, 45(2), 155-165 (2017-09-28)
Changes in Soluble CD18 in Murine Autoimmune Arthritis and Rheumatoid Arthritis Reflect Disease Establishment and Treatment Response.Tue Wenzel Kragstrup et al.PloS one, 11(2), e0148486-e0148486 (2016-02-06)
PAMP induced expression of immune relevant genes in head kidney leukocytes of rainbow trout (Oncorhynchus mykiss)Chettri JK, et al. Developmental and Comparative Immunology, 35(4), 476-482 (2011)
FACIN, a Double-Edged Sword of the Emerging Periodontal Pathogen Filifactor alocis: A Metabolic Enzyme Moonlighting as a Complement Inhibitor.Monika Jusko et al.Journal of immunology (Baltimore, Md. : 1950), 197(8), 3245-3259 (2016-09-18)
Identification and expression analysis of a TLR11 family gene in the sea urchin Strongylocentrotus intermedius.Yinan Wang et al.Immunogenetics, 70(5), 337-346 (2017-10-28)
LMIR5 extracellular domain activates myeloid cells through toll-like receptor 4.Vongsavanh Phongsisay et al.Molecular immunology, 62(1), 169-177 (2014-07-09)
Sodium polyanethole sulfonate as an inhibitor of activation of complement function in blood culture systems.Yaseelan Palarasah et al.Journal of clinical microbiology, 48(3), 908-914 (2010-01-01)
Functional assessment of mouse complement pathway activities and quantification of C3b/C3c/iC3b in an experimental model of mouse renal ischaemia/reperfusion injury.Juha P Kotimaa et al.Journal of immunological methods, 419, 25-34 (2015-03-04)
Self-mineralizing Ca-enriched Methacrylated Gellan Gum Beads for Bone Tissue EngineeringVieiraS, et al. Acta Biomaterialia (2019)
Factor H-IgG Chimeric Proteins as a Therapeutic Approach against the Gram-Positive Bacterial PathogenAnna M Blom et al.Journal of immunology (Baltimore, Md. : 1950), 199(11), 3828-3839 (2017-11-01)
Dectin-1/2-induced autocrine PGE2 signaling licenses dendritic cells to prime Th2 responses.Maria M M Kaisar et al.PLoS biology, 16(4), e2005504-e2005504 (2018-04-19)
Inhibition of neogenin fosters resolution of inflammation and tissue regeneration.Martin Schlegel et al.The Journal of clinical investigation, 128(10), 4711-4726 (2018-09-18)
The role of properdin in murine zymosan-induced arthritis.Petya Dimitrova et al.Molecular immunology, 47(7-8), 1458-1466 (2010-03-17)
Systematic Identification of Host Cell Regulators of Legionella pneumophila Pathogenesis Using a Genome-wide CRISPR Screen.Edwin E Jeng et al.Cell host & microbe, 26(4), 551-563 (2019-09-22)
Eosinophil chemiluminescence response to cytokines and opsonized zymosans in atopic dermatitis.M Miyasato et al.International archives of allergy and immunology, 104 Suppl 1(1), 24-26 (1994-01-01)
Identification of a critical sulfation in chondroitin that inhibits axonal regeneration.Craig S Pearson et al.eLife, 7 (2018-05-16)
β-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection: a Crucial Role for IL-32.Jéssica Cristina Dos Santos et al.Cell reports, 28(10), 2659-2672 (2019-09-05)
TREM2 suppresses the proinflammatory response to facilitate PRRSV infection via PI3K/NF-κB signaling.Zhenbang Zhu et al.PLoS pathogens, 16(5), e1008543-e1008543 (2020-05-14)
Aqueous and methanolic extracts of Caulerpa mexicana suppress cell migration and ear edema induced by inflammatory agents.Mariana Angelica Oliveira Bitencourt et al.Marine drugs, 9(8), 1332-1345 (2011-09-06)
C-type lectin Mincle is an activating receptor for pathogenic fungus, Malassezia.Sho Yamasaki et al.Proceedings of the National Academy of Sciences of the United States of America, 106(6), 1897-1902 (2009-01-28)
The role of properdin in zymosan-and Escherichia coli-induced complement activationHarboe M, et al. Journal of Immunology, 1200269-1200269 (2012)
Inhibition of Δ24-dehydrocholesterol reductase activates pro-resolving lipid mediator biosynthesis and inflammation resolution.Andreas Körner et al.Proceedings of the National Academy of Sciences of the United States of America, 116(41), 20623-20634 (2019-09-25)
Iodide-doped precious metal nanoparticles: measuring oxidative stress in vivo via photoacoustic imaging.Yash Mantri et al.Nanoscale, 12(19), 10511-10520 (2020-05-13)
Fermented Animal Source Protein as Substitution of Fishmeal on Intestinal Microbiota, Immune-Related Cytokines and Resistance to Vibrio mimicus in Freshwater Crayfish (Cherax cainii).Muhammad A B Siddik et al.Frontiers in physiology, 10, 1635-1635 (2020-02-23)
Protection by mTOR Inhibition on Zymosan-Induced Systemic Inflammatory Response and Oxidative/Nitrosative Stress: Contribution of mTOR/MEK1/ERK1/2/IKKβ/IκB-α/NF-κB Signalling Pathway.Seyhan Sahan-Firat et al.Inflammation, 41(1), 276-298 (2017-11-08)
Inflammation induces stress erythropoiesis through heme-dependent activation of SPI-C.Laura F Bennett et al.Science signaling, 12(598) (2019-09-12)
Orange-spotted grouper Epinephelus coioides that have encountered low salinity stress have decreased cellular and humoral immune reactions and increased susceptibility to Vibrio alginolyticus.Yu-Yuan Chen et al.Fish & shellfish immunology, 80, 392-396 (2018-06-19)
Type I Interferon Response Dysregulates Host Iron Homeostasis and Enhances Candida glabrata Infection.Michael Riedelberger et al.Cell host & microbe, 27(3), 454-466 (2020-02-23)
Macrophage activation and differentiation signals regulate schlafen-4 gene expression: evidence for Schlafen-4 as a modulator of myelopoiesis.Wendy J van Zuylen et al.PloS one, 6(1), e15723-e15723 (2011-01-21)
Characterization of nuclear factor of activated T-cells-c3 (NFATc3) and gene expression of upstream-downstream signaling molecules in response to immunostimulants in Pacific red snapper cells.Carlos Angulo et al.Developmental and comparative immunology, 78, 149-159 (2017-10-08)
A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity.Henrik Pedersen et al.Journal of immunology (Baltimore, Md. : 1950), 205(8), 2287-2300 (2020-09-18)
Aldosterone induces trained immunity: the role of fatty acid synthesis.Charlotte D C C van der Heijden et al.Cardiovascular research, 116(2), 317-328 (2019-05-24)
Variation in the hemostatic complement (C5a) responses to in vitro nitrogen bubbles in monodontids and phocids.Laura A Thompson et al.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 190(6), 811-822 (2020-08-21)
Aggravating action of zymosan on acute liver damage in perfused liver of rats treated with D-galactosamine.T X Cui et al.The American journal of physiology, 275(6 Pt 1), G1361-G1366 (1998-12-09)
Variants in nicotinamide adenine dinucleotide phosphate oxidase complex components determine susceptibility to very early onset inflammatory bowel disease.Sandeep S Dhillon et al.Gastroenterology, 147(3), 680-689 (2014-06-17)
C-reactive protein (CRP) recognizes uric acid crystals and recruits proteases C1 and MASP1.Anika Alberts et al.Scientific reports, 10(1), 6391-6391 (2020-04-15)
Experimental evidences that P21 protein controls Trypanosoma cruzi replication and modulates the pathogenesis of infection.Thaise L Teixeira et al.Microbial pathogenesis, 135, 103618-103618 (2019-07-17)
C-type lectin 17A and macrophage-expressed receptor genes are magnified by fungal β-glucan after Vibrio parahaemolyticus infection in Totoaba macdonaldi cells.Carlos Angulo et al.Immunobiology, 224(1), 102-109 (2018-12-01)
Sterigmatomyces halophilus β-glucan improves the immune response and bacterial resistance in Pacific red snapper (Lutjanus peru) peripheral blood leucocytes: In vitro study.Martha Reyes-Becerril et al.Fish & shellfish immunology, 78, 392-403 (2018-04-24)
Liver-Targeted Anti-HBV Single-Stranded Oligonucleotides with Locked Nucleic Acid Potently Reduce HBV Gene Expression In Vivo.Hassan Javanbakht et al.Molecular therapy. Nucleic acids, 11, 441-454 (2018-06-03)
C-Type Lectin Receptor MCL Facilitates Mincle Expression and Signaling through Complex Formation.Yasunobu Miyake et al.Journal of immunology (Baltimore, Md. : 1950), 194(11), 5366-5374 (2015-04-19)
Development and characterization of stable reporter cells for fast and sensitive detection of pyrogen.Kaili Li et al.Analytical biochemistry, 557, 69-76 (2018-07-22)
In vitro immunostimulatory potential of fungal β-glucans in pacific red snapper (Lutjanus peru) cells.Tomás Cárdenas-Reyna et al.Developmental and comparative immunology, 77, 350-358 (2017-09-11)
Screening biomaterials for functional complement activation in serum.Daniel B Lyle et al.Journal of biomedical materials research. Part A, 92(1), 205-213 (2009-01-28)
IgG Immunocomplexes Sensitize Human Monocytes for Inflammatory Hyperactivity via Transcriptomic and Epigenetic Reprogramming in Rheumatoid Arthritis.Qiao Zhong et al.Journal of immunology (Baltimore, Md. : 1950), 200(12), 3913-3925 (2018-05-02)
Impact of copper nanoparticles on porcine neutrophils: ultrasensitive characterization factor combining chemiluminescence information and USEtox assessment modelPu Y, et al. Materials Today Communications, 11, 68-75 (2017)
The G2A receptor controls polarization of macrophage by determining their localization within the inflamed tissueKern K, et al. Frontiers in Immunology, 9, 2261-2261 (2018)
Self-mineralizing Ca-enriched methacrylated gellan gum beads for bone tissue engineering.Sílvia Vieira et al.Acta biomaterialia, 93, 74-85 (2019-02-02)
Expression of factor V by resident macrophages boosts host defense in the peritoneal cavity.Nan Zhang et al.The Journal of experimental medicine, 216(6), 1291-1300 (2019-05-03)
Molecular and functional characterization of mouse S5D-SRCRB: a new group B member of the scavenger receptor cysteine-rich superfamily.Cristina Miró-Julià et al.Journal of immunology (Baltimore, Md. : 1950), 186(4), 2344-2354 (2011-01-11)
Immunomodulatory activity of oenothein B isolated from Epilobium angustifolium.Igor A Schepetkin et al.Journal of immunology (Baltimore, Md. : 1950), 183(10), 6754-6766 (2009-10-23)
High-fat diet increases pain behaviors in rats with or without obesity.Zongbin Song et al.Scientific reports, 7(1), 10350-10350 (2017-09-06)
Cyclic AMP-dependent positive feedback signaling pathways in the cortex contributes to visceral pain.Shui-Bing Liu et al.Journal of neurochemistry, 153(2), 252-263 (2019-10-31)
In vitro investigations on the effects of semi-synthetic, sulphated carbohydrates on the immune status of cultured common carp (Cyprinus carpio) leucocytes.N Kareem et al.Fish & shellfish immunology, 74, 213-222 (2018-01-01)
Candida albicans mannans mediate Streptococcus mutans exoenzyme GtfB binding to modulate cross-kingdom biofilm development in vivo.Geelsu Hwang et al.PLoS pathogens, 13(6), e1006407-e1006407 (2017-06-16)
Toll-Like Receptors and Dectin-1, a C-Type Lectin Receptor, Trigger Divergent Functions in CNS Macrophages.John C Gensel et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(27), 9966-9976 (2015-07-15)
Heme oxygenase-1-Dependent anti-inflammatory effects of atorvastatin in zymosan-injected subcutaneous air pouch in mice.Ghewa A El-Achkar et al.PloS one, 14(5), e0216405-e0216405 (2019-05-10)
A Metalloproteinase Mirolysin of Tannerella forsythia Inhibits All Pathways of the Complement System.Monika Jusko et al.Journal of immunology (Baltimore, Md. : 1950), 195(5), 2231-2240 (2015-07-26)
Phagocytes from Mice Lacking the Sts Phosphatases Have an Enhanced Antifungal Response to Candida albicans.David Frank et al.mBio, 9(4) (2018-07-19)
Strain-Specific Manifestation of Lupus-like Systemic Autoimmunity Caused by Zap70 Mutation.Takashi Matsuo et al.Journal of immunology (Baltimore, Md. : 1950), 202(11), 3161-3172 (2019-04-26)
Keratinocyte growth factor augments pulmonary innate immunity through epithelium-driven, GM-CSF-dependent paracrine activation of alveolar macrophages.Huixing Wu et al.The Journal of biological chemistry, 286(17), 14932-14940 (2011-02-24)
Signaling and functional competency of neutrophils derived from bone-marrow cells expressing the ER-HOXB8 oncoprotein.Stephanie Saul et al.Journal of leukocyte biology, 106(5), 1101-1115 (2019-06-20)
β-glucan administration induces metabolic changes and differential survival rates after bacterial or viral infection in turbot (Scophthalmus maximus).Marta Librán-Pérez et al.Fish & shellfish immunology, 82, 173-182 (2018-08-07)
Protective effects of zymosan on heat stress-induced immunosuppression and apoptosis in dairy cows and peripheral blood mononuclear cellsSun Y, et al. Cell Stress & Chaperones, 23(5), 1069-1078 (2018)
SCIMP is a universal Toll-like receptor adaptor in macrophages.Lin Luo et al.Journal of leukocyte biology, 107(2), 251-262 (2019-08-31)
Complement Receptor 2 Based Immunoassay Measuring Activation of the Complement System at C3-Level in Plasma Samples From Mice and Humans.Lene Halkjær et al.Frontiers in immunology, 11, 774-774 (2020-05-21)
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